云南高校图书馆联盟文献共享服务平台- PYROPTOSIS

PYROPTOSIS: 作品数：312被引量：1968H指数：23; 导出分析报告; 相关领域：生物学更多>>; 相关作者：方向明董朝飞潘经锐王艺东孙东杰更多>>; 相关机构：浙江大学医学院附属第一医院中山大学孙逸仙纪念医院南京大学郑州大学更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金国家重点基础研究发展计划广东省自然科学基金中国博士后科学基金更多>>

Pyroptosis,ferroptosis,and autophagy in spinal cord injury:regulatory mechanisms and therapeutic targets: 《Neural Regeneration Research》2025年第10期2787-2806,共20页Qingcong Zheng Du Wang Rongjie Lin Weihong Xu; supported by the Natural Science Foundation of Fujian Province,No.2021J02035(to WX).; Regulated cell death is a form of cell death that is actively controlled by biomolecules.Several studies have shown that regulated cell death plays a key role after spinal cord injury.Pyroptosis and ferroptosis are ne...; 关键词：AUTOPHAGY cell death ferroptosis INFLAMMATION pathological mechanisms PYROPTOSIS regulated cell death regulatory pathways spinal cord injury therapeutic targets

Inhibiting ceramide synthase 5 expression in microglia decreases neuroinflammation after spinal cord injury: 《Neural Regeneration Research》2025年第10期2955-2968,共14页Wei Zhang Yubao Lu Ruoqi Shen Yingjie Wu Chenrui Liu Xingxing Fang Liangming Zhang Bin Liu Limin Rong; supported by grants from the National Key Research and Development Program of China,No.2017YFA0105400(to LR);the Key Research and Development Program of Guangdong Province,No.2019B020236002(to LR);the National Natural Science Foundation of China,Nos.81972111(to LZ),81772349(to BL).; Microglia,the resident monocyte of the central nervous system,play a crucial role in the response to spinal cord injury.However,the precise mechanism remains unclear.To investigate the molecular mechanisms by which mi...; 关键词：ceramide synthase 5 gasdermin D MICROGLIA NEUROINFLAMMATION NLRP3 nuclear factor kappa B Pla2g7 PYROPTOSIS sphingomyelin metabolism spinal cord injury

Neuronal regulated cell death in aging-related neurodegenerative diseases:key pathways and therapeutic potentials: 《Neural Regeneration Research》2025年第8期2245-2263,共19页Run Song Shiyi Yin Jiannan Wu Junqiang Yan; supported by the Key Projects of Medical Science and Technology of Henan Province,No.SBGJ202002099(to JY)。; Regulated cell death(such as apoptosis,necroptosis,pyroptosis,autophagy,cuproptosis,ferroptosis,disulfidptosis)involves complex signaling pathways and molecular effectors,and has been proven to be an important regulat...; 关键词：apoptosis autophagy cuproptosis disulfidptosis ferroptosis NECROPTOSIS neurodegenerative disease neurological aging diseases PANoptosis PYROPTOSIS

Neuroprotective potential for mitigating ischemia-reperfusion-induced damage: 《Neural Regeneration Research》2025年第8期2199-2217,共19页Zi Ye Runqing Liu Hangxing Wang Aizhen Zuo Cen Jin Nan Wang Huiqi Sun Luqian Feng Hua Yang; Reperfusion following cerebral ischemia causes both structural and functional damage to brain tissue and could aggravate a patient's condition;this phenomenon is known as cerebral ischemia-reperfusion injury.Current s...; 关键词：apoptosis autophagy blood-brain barrier dietary supplements drug HORMONES inflammation NEUROPROTECTION oxidative stress prognosis PYROPTOSIS reperfusion injury risk factors RNA THERAPEUTICS

Inflammasome links traumatic brain injury, chronic traumatic encephalopathy, and Alzheimer's disease被引量：1: 《Neural Regeneration Research》2025年第6期1644-1664,共21页Gabriela Seplovich Yazan Bouchi Juan Pablo de Rivero Vaccari Jennifer C.Munoz Pareja Andrew Reisner Laura Blackwell Yehia Mechref Kevin K.Wang J.Adrian Tyndall Binu Tharakan Firas Kobeissy; Traumatic brain injury, chronic traumatic encephalopathy, and Alzheimer's disease are three distinct neurological disorders that share common pathophysiological mechanisms involving neuroinflammation. One sequela of n...; 关键词：Alzheimer's disease caspase-1 chronic traumatic encephalopathy INFLAMMASOMES NEURODEGENERATION neuroinflammation NLRP1 NLRP3 PYROPTOSIS TAUOPATHY traumatic brain injury

Role of ubiquitin-specific proteases in programmed cell death of breast cancer cells: 《Genes & Diseases》2025年第3期319-328,共10页Wen Yan Shasha Xiang Jianbo Feng Xuyu Zu; supported by grants from University of South China Innovation Foundation For Postgraduate(233YXC001);Postgraduate Scientific Research Innovation Project of Hunan Province(CX20230955);the National Natural Science Foundation of China(No.82103171,Jianbo Feng);the Clinical Medical Research“4310”Program of the University of South China(20224310NHYCG07).; Breast cancer (BC) is the most common malignant tumor and the leading cause ofcancer-related deaths among women worldwide. Great progress has been recently achieved incontrolling breast cancer;however, mortality from ...; 关键词：ANOIKIS Apoptosis AUTOPHAGY Breast cancer Ferroptosis PYROPTOSIS Ubiquitin-specific proteases

Electroacupuncture Promotes Gastric Motility by Suppressing Pyroptosis via NLRP3/Caspase-1/GSDMD Signaling Pathway in Diabetic Gastroparesis Rats: 《Chinese Journal of Integrative Medicine》2025年第5期448-457,共10页HUANG Hao PENG Yan XIAO Le WANG Jing XIN Yu-hong ZHANG Tian-hua LI Xiao-yu WEI Xing; Supported by the National Natural Science Foundation of China(No.81774431);Hunan Provincial Natural Science Foundation of China(No.2022JJ40310 and 2024JJ5306);Scientific Research Fund of Hunan Provincial Education Department(No.22A0275);Changsha Municipal Natural Science Foundation(No.kq2202263)。; Objective:To investigate the mechanism of electroacupuncture(EA)in treating diabetic gastroparesis(DGP)by inhibiting the activation of Nod-like receptor family pyrin domain-containing protein 3(NLRP3)inflammasome and ...; 关键词：ELECTROACUPUNCTURE diabetic gastroparesis PYROPTOSIS Nod-like receptor family pyrin domain-containing protein 3 cysteinyl aspartate specific proteinase-1 gasdermin D

Cisplatin induces acute liver injury by triggering caspase-3/GSDME-me diate d cell pyroptosis: 《Hepatobiliary & Pancreatic Diseases International》2025年第2期177-187,共11页Ping-Ping Wu Xiu-Jin Shen Shu-Sen Zheng; supported by grants from the National Natural Science Foundation of China(8170060495 and 82170682)。; Background:Cisplatin triggers Gasdermin E(GSDME)cleavage,causing membrane bubble formation,content release,and inflammation.Caspase-3 activation initiates GSDME cleavage,and thus inhibiting this pathway mitigates cisp...; 关键词：CISPLATIN PYROPTOSIS HEPATOTOXICITY Gasdermins GSDME

Hypoxia-preconditioned bone marrow-derived mesenchymal stem cells protect neurons from cardiac arrest-induced pyroptosis被引量：1: 《Neural Regeneration Research》2025年第4期1103-1123,共21页Xiahong Tang Nan Zheng Qingming Lin Yan You Zheng Gong Yangping Zhuang Jiali Wu Yu Wang Hanlin Huang Jun Ke Feng Chen; supported by the Natural Science Fund of Fujian Province,No.2020J011058(to JK);the Project of Fujian Provincial Hospital for High-level Hospital Construction,No.2020HSJJ12(to JK);the Fujian Provincial Finance Department Special Fund,No.(2021)848(to FC);the Fujian Provincial Major Scientific and Technological Special Projects on Health,No.2022ZD01008(to FC).; Cardiac arrest can lead to severe neurological impairment as a result of inflammation,mitochondrial dysfunction,and post-cardiopulmonary resuscitation neurological damage.Hypoxic preconditioning has been shown to impr...; 关键词：bone marrow–derived mesenchymal stem cells cardiac arrest cardiac resuscitation hypoxic preconditioning liver isoform of phosphofructokinase mitochondria NEUROINFLAMMATION oxidative stress PYROPTOSIS reactive oxygen species

The novel BCL-2/BCL-XL inhibitor APG-1252-mediated cleavage of GSDME enhances the antitumor efficacy of HER2-targeted therapy in HER2-positive gastric cancer: 《Acta Pharmacologica Sinica》2025年第4期1082-1096,共15页Qiu-yun Luo Jing Yang Tian Di Zeng-fei Xia Lin Zhang Wen-tao Pan Shan Shi Li-qiong Yang Jian Sun Miao-zhen Qiu Da-jun Yang; supported by the National Natural Science Foundation of China(NSFC:82172748 and 82073377);the Guangdong Basic and Applied Basic Research Foundation(2024B1515020120 and 2023A1515110567);the Medical Scientific Research Foundation of Guangdong Province(A2024171).; HER2-positive gastric cancer has a poor prognosis,with a high incidence of drug resistance and a lack of effective treatments for drug-resistant patients.The exploration of the mechanism of resistance to HER2-targeted...; 关键词：HER2-positive gastric cancer GSDME PYROPTOSIS APG-1252

高级检索 检索式检索

时间限定

期刊范围

学科限定全选

高级检索 检索式检索

时间限定

期刊范围

学科限定全选

PYROPTOSIS

检索结果分析

下载全文

高级检索检索式检索

时间限定

期刊范围

学科限定全选

高级检索 检索式检索

时间限定

期刊范围

学科限定全选

PYROPTOSIS

检索结果分析

下载全文

用户登录

高级检索检索式检索