INFLAMMASOMES

作品数：45被引量：220H指数：10
导出分析报告
相关领域：医药卫生生物学更多>>
相关作者：薛梅吕社民徐光华吴殿磊更多>>
相关机构：中国中医科学院西苑医院延安大学西安交通大学更多>>
相关期刊：《Cellular & Molecular Immunology》《Chinese Journal of Integrative Medicine》《Chinese Journal of Natural Medicines》《Acta Pharmacologica Sinica》更多>>
相关基金：国家自然科学基金北京市自然科学基金中国博士后科学基金上海市科学技术委员会科研基金更多>>
-
在结果中检索

检索结果分析

结果分析中...
共 条 记 录，以下是1-10
全选清除导出
参考文献引证文献引用追踪
视图：
排序：
Inflammasome links traumatic brain injury, chronic traumatic encephalopathy, and Alzheimer's disease被引量：1
《Neural Regeneration Research》2025年第6期1644-1664,共21页Gabriela Seplovich Yazan Bouchi Juan Pablo de Rivero Vaccari Jennifer C.Munoz Pareja Andrew Reisner Laura Blackwell Yehia Mechref Kevin K.Wang J.Adrian Tyndall Binu Tharakan Firas Kobeissy 
Traumatic brain injury, chronic traumatic encephalopathy, and Alzheimer's disease are three distinct neurological disorders that share common pathophysiological mechanisms involving neuroinflammation. One sequela of n...
关键词：Alzheimer's disease caspase-1 chronic traumatic encephalopathy INFLAMMASOMES NEURODEGENERATION neuroinflammation NLRP1 NLRP3 PYROPTOSIS TAUOPATHY traumatic brain injury 
Inflammasomes and their roles in autoimmune diseases
《Rheumatology & Autoimmunity》2024年第4期197-217,共21页Minghui Pan Jie Yang Zhengfan Jiang 
supported by the Ministry of Science and Technology of the People's Republic of China,Grant/Award Number:2023YFC2306102;National Natural Science Foundation of China,Grant/Award Number:32130038.
Autoimmune diseases are immune disorders in which the immune system mistakenly targets and attacks the normal cells,tissues,and organs of the patients.The etiology of autoimmune diseases is complex and multifactorial....
关键词：autoimmune diseases INFLAMMASOMES INFLAMMATION pro-inflammatory cytokines 
Bufei Huoxue capsule(补肺活血胶囊)alleviates silicosis by inhibiting the activation of nucleotide-like receptor containing pyrin domain 3 inflammasome and macrophages polarization based on network pharmacology
《Journal of Traditional Chinese Medicine》2024年第6期1236-1246,共11页HANG Wenlu WANG Lin BO Yun ZUO Shurun WANG Songquan LI Haiquan BU Chunlu ZHAO Jie ZHOU Xianmei 
Jiangsu Natural Science Foundation Youth Program:Regulation of Alveolar Macrophage Pyroptosis based on (Never in Mitosis Gene A)-Related Kinase 7/Nucleotide-like Receptor Containing Pyrin Domain 3 Inflammasome to Explore the Mechanism of Bufei Huoxue Capsule on Pulmonary Fibrosis in Silicosis (No. BK20220236);Key Research and Development Project of Xuzhou City:Evaluation of Pyroptosis Induced by Nucleotide-like Receptor Containing Pyrin Domain 3 Inflammasome Activation in Pneumoconiosis Patients by Bronchoalveolar Lavage Fluid Ion Assay Combined with High-Resolution Computed Tomography Quantitative Analysis (KC22212);Youth Medical Science and Technology Innovation Project of Xuzhou Municipal Health Commission and Development Fund of Affiliated Hospital of Xuzhou Medical University:Study on the Regulation of Various Cytokines and the Effect of c-Jun Activation Domain-Binding Protein 1 on Immune Response in Lung Cancer (XWKYHT20210565, XYFY2020051)。
OBJECTIVE: To predict the targets of Bufei Huoxue capsule( 补肺活血胶囊, BFHX) using network pharmacology analysis and to explore its effects and functional targets in a silicotic rat model. METHODS: The drug and dise...
关键词：SILICOSIS pulmonary fibrosis NLR proteins INFLAMMASOMES PYROPTOSIS Bufei Huoxue capsule 
Effects of Rutaecarpine on Chronic Atrophic Gastritis Through Nucleotide-binding Oligomerization Domain-like Receptors and Inflammasomes
《World Journal of Traditional Chinese Medicine》2024年第3期303-315,共13页Yong He Xin Wang Li-Sheng Chen Lei Chang Ting-Ting He Ao-Zhe Zhang Hao-Tian Li Shi-Zhang Wei Man-Yi Jing Yan-Ling Zhao 
supported by the Major Program of the National Natural Science Foundation of China (No. 82192915);the National Key Research and Development Program (No. 2018YFC1704500)
Objective: Chronic atrophic gastritis(CAG) is a complex and burdensome disease. However, side effects and compliance issues cannot be ignored due to the long treatment cycle. Numerous studies have confirmed the effect...
关键词：Chronic atrophic gastritis infiammasome nucleotide‑binding oligomerization domain‑like receptors PYROPTOSIS RUTAECARPINE 
Membrane vesicles derived from Streptococcus suis serotype 2 induce cell pyroptosis in endothelial cells via the NLRP3/Caspase-1/GSDMD pathway
《Journal of Integrative Agriculture》2024年第4期1338-1353,共16页Keda Shi Yan Li Minsheng Xu Kunli Zhang Hongchao Gou Chunling Li Shaolun Zhai 
supported by the National Natural Science Foundation of China(U22A20520);the Innovation Team Project of Modern Agricultural Industrial Technology System of Guangdong Province,China(2023KJ119);the Natural Science Foundation Program of Guangdong Province,China(2023A1515012206)。
Streptococcus suis serotype 2(S.suis 2)is a zoonotic pathogen that clinically causes severe swine and human infections(such as meningitis,endocarditis,and septicemia).In order to cause widespread diseases in different...
关键词：Streptococcus suis serotype 2 membrane vesicles ENDOCYTOSIS PYROPTOSIS NLRP3 inflammasomes mitochondrial damage endothelial cell 
Inflammasomes in neurodegenerative diseases
《Translational Neurodegeneration》2024年第1期71-92,共22页Qianchen Wang Songwei Yang Xuan Zhang Shanshan Zhang Liping Chen Wanxue Wang Naihong Chen Jiaqing Yan 
supported by grants from National Natural Science Foundation of China(82003973);National Natural Science Foundation of China(82304750);Hunan University of Chinese Medicine Research Fund Outstanding Youth Project(Z2023XJYQ02).
Inflammasomes represent a crucial component of the innate immune system,which respond to threats by recognizing different molecules.These are known as pathogen-associated molecular patterns(PAMPs)or host-derived damag...
关键词：INFLAMMASOME Neurodegenerative diseases NEURODEGENERATION NEUROINFLAMMATION MICROGLIA 
The role of inflammasomes in human diseases and their potential as therapeutic targets被引量：6
《Signal Transduction and Targeted Therapy》2024年第2期479-508,共30页Jing Yao Keenan Sterling Zhe Wang Yun Zhang Weihong Song 
supported by the Key Laboratory of Alzheimer’s Disease of Zhejiang Province(ZJAD-2021004);the National Natural Science Foundation of China(82201576);Beijing Hospitals Authority Youth Programme(QML20210804);Beijing Medical Research 2021-8(YZ);the National Natural Science Foundation of China(82150710557,82230043 and 82293642)to WS.
Inflammasomes are large protein complexes that play a major role in sensing inflammatory signals and triggering the innate immune response.Each inflammasome complex has three major components:an upstream sensor molecu...
关键词：inflam THERAPEUTIC POTENTIAL 
The role of innate immunity in diabetic nephropathy and their therapeutic consequences被引量：4
《Journal of Pharmaceutical Analysis》2024年第1期39-51,共13页Min Yang Chun Zhang 
financially supported by the National Natural Science Foundation of China(Grant Nos.:82100801,81974096,81770711,81974097,and 81961138007).
Diabetic nephropathy (DN) is an enduring condition that leads to inflammation and affects a substantial number of individuals with diabetes worldwide. A gradual reduction in glomerular filtration and emergence of prot...
关键词：Innate immunity Diabetic nephropathy INFLAMMATION Toll-like receptor INFLAMMASOMES 
The impact of human umbilical cord-derived mesenchymal stem cells on the pancreatic function of type 2 diabetic mice and their regulatory role on NLRP3 inflammasomes
《China Medical Abstracts(Internal Medicine)》2023年第4期209-210,共2页王杰 
Objective To investigate the effect and regulation of umbilical cord-derived mesenchymal stem cells(UCMSCs)on islets function and NOD-like receptor family,pyrin domain containing 3(NLRP3)and autophagy in type 2 diabet...
关键词：NLRP3 DIABETIC function 
The implication of pyroptosis in cancer immunology:Current advances and prospects被引量：1
《Genes & Diseases》2023年第6期2339-2350,共12页Wei Liu Jinwu Peng Muzhang Xiao Yuan Cai Bi Peng Wenqin Zhang Jianbo Li Fanhua Kang Qianhui Hong Qiuju Liang Yuanliang Yan Zhijie Xu 
supported by grants from the Natural Science Foundation of Hunan Province,China(No.2021JJ30904 and 2020JJ5934);the Science and Technology Innovation Program of Hunan Province,China(2021RC3029);the China Postdoctoral Science Foundation(China)(No.2021T140754 and 2020M672521).
Pyroptosis is a regulated cell death pathway involved in numerous human diseases,especially malignant tumors.Recent studies have identified multiple pyroptosis-associated signaling molecules,like caspases,gasdermin fa...
关键词：Cancer immunology Immune response IMMUNOTHERAPY PYROPTOSIS INFLAMMASOMES 
全选清除导出
共5页<12345>
检索报告 对象比较 聚类工具 使用帮助 返回顶部