SILICOSIS

作品数：44被引量：153H指数：8
导出分析报告
相关作者：谢强敏汤慧芳陈季强卞如濂张玉更多>>
相关机构：南京市胸科医院浙江大学河北联合大学山东省职业卫生与职业病防治研究院更多>>
相关期刊：《Acta Geochimica》《Signal Transduction and Targeted Therapy》《Genes & Diseases》《Journal of Biomedical Research》更多>>
相关基金：国家自然科学基金河北省自然科学基金中国博士后科学基金更多>>
-
在结果中检索

检索结果分析

结果分析中...
共 条 记 录，以下是1-10
全选清除导出
参考文献引证文献引用追踪
视图：
排序：
Time-series transcriptome analysis mapping pulmonary immune checkpoint atlas of experimental silicosis
《Genes & Diseases》2025年第1期126-129,共4页Youliang Zhao Yuanmeng Qi Meixiu Duan Changfu Hao Wu Yao 
supported by the National Natural Science Foundation of China(No.U1904209,82241093).
Silicosis is a chronic interstitial lung disease caused by prolonged exposure to inhalable silica particles.The initiation and progression of silicosis involve a dynamic process encompassing various cell types and mol...
关键词：SILICOSIS HOMEOSTASIS MAPPING 
Effect of macrophage- to- myofibroblast transition on silicosis
《Animal Models and Experimental Medicine》2025年第2期363-371,共9页Fei Geng Jingrou Xu Xichen Ren Ying Zhao Yuhao Cai Yaqian Li Fuyu Jin Tian Li Xuemin Gao Wenchen Cai Hong Xu Zhongqiu Wei Na Mao Ying Sun Fang Yang 
The National Natural Science Foundation of China(no.82204006);the Science and Technology of Project of Hebei Education Department(QN2022009);the Provincial Graduate Student Innovation Funding Project of Hebei Province(CXZZBS2022104);the National Natural Science Foundation of Hebei Province(H2020209292).
Background:The aim was to explore the effect of macrophage polarization and macrophage-to-myofibroblast transition(MMT)in silicosis.Methods:Male Wistar rats were divided into a control group and a silicosis group deve...
关键词：MACROPHAGE macrophage-to-myofibroblast transition SILICOSIS 
Bufei Huoxue capsule(补肺活血胶囊)alleviates silicosis by inhibiting the activation of nucleotide-like receptor containing pyrin domain 3 inflammasome and macrophages polarization based on network pharmacology
《Journal of Traditional Chinese Medicine》2024年第6期1236-1246,共11页HANG Wenlu WANG Lin BO Yun ZUO Shurun WANG Songquan LI Haiquan BU Chunlu ZHAO Jie ZHOU Xianmei 
Jiangsu Natural Science Foundation Youth Program:Regulation of Alveolar Macrophage Pyroptosis based on (Never in Mitosis Gene A)-Related Kinase 7/Nucleotide-like Receptor Containing Pyrin Domain 3 Inflammasome to Explore the Mechanism of Bufei Huoxue Capsule on Pulmonary Fibrosis in Silicosis (No. BK20220236);Key Research and Development Project of Xuzhou City:Evaluation of Pyroptosis Induced by Nucleotide-like Receptor Containing Pyrin Domain 3 Inflammasome Activation in Pneumoconiosis Patients by Bronchoalveolar Lavage Fluid Ion Assay Combined with High-Resolution Computed Tomography Quantitative Analysis (KC22212);Youth Medical Science and Technology Innovation Project of Xuzhou Municipal Health Commission and Development Fund of Affiliated Hospital of Xuzhou Medical University:Study on the Regulation of Various Cytokines and the Effect of c-Jun Activation Domain-Binding Protein 1 on Immune Response in Lung Cancer (XWKYHT20210565, XYFY2020051)。
OBJECTIVE: To predict the targets of Bufei Huoxue capsule( 补肺活血胶囊, BFHX) using network pharmacology analysis and to explore its effects and functional targets in a silicotic rat model. METHODS: The drug and dise...
关键词：SILICOSIS pulmonary fibrosis NLR proteins INFLAMMASOMES PYROPTOSIS Bufei Huoxue capsule 
Integration of serum pharmacochemistry with network pharmacology to reveal the potential mechanism of Yangqing Chenfei formula(养清尘肺方) for the treatment of silicosis
《Journal of Traditional Chinese Medicine》2024年第4期784-793,共10页HU Yuanyuan LIU Xinguang ZHAO Peng WU Jinyan YAN Xinhua HOU Runsu WANG Xiangcheng YANG Fan TIAN Xinrong LI Jiansheng 
Special Project of Traditional Chinese Medicine Research in Henan Province:Evaluation and Characteristics of the Therapeutic Effect of Dialectical Treatment for Coal Worker Pneumoconiosis Based on Multicenter,Randomized,Double-Blind,and Parallel Controlled Trials(No.20-21ZYZD01)。
OBJECTIVE:To explore the mechanisms of Yangqing Chenfei formula(养清尘肺方,YCF)in the treatment of silicosis through a comprehensive strategy consisting of serum pharmacochemistry,network pharmacology analysis,and in ...
关键词：SILICOSIS network TREATMENT 
SiO_(2) Induces Iron Overload and Ferroptosis in Cardiomyocytes in a Silicosis Mouse Model
《Biomedical and Environmental Sciences》2024年第6期617-627,共11页Yongheng Wang Ning Li Yi Guan Tong LI Yuxiu Zhang Hong Cao Zhihua Yu Zhiheng Li Shuoyan Li Jiahao Hu Wenxin Zhou Sisi Qin Shuang Li Sanqiao Yao 
supported by the National Natural Science Foundation of China[No.U21A20334,82373544];Hebei Provincial Department of Science and Technology Centrally Guided Local Development Fund Project[236Z7705G];Occupational health risk assessment and the formulation of national occupational health standards[102393220020090000020].
Objective The aim of this study was to explore the role and mechanism of ferroptosis in SiO_(2)-induced cardiac injury using a mouse model.Methods Male C57BL/6 mice were intratracheally instilled with SiO_(2) to creat...
关键词：SiO_(2) exposure Iron overload Ferroptosis Cardiac injury NRF2 
circPVT1 promotes silica-induced epithelial-mesenchymal transition by modulating the miR-497-5p/TCF3 axis
《Journal of Biomedical Research》2024年第2期163-174,I0011-I0015,共17页Siyun Zhou Yan Li Wenqing Sun Dongyu Ma Yi Liu Demin Cheng Guanru Li Chunhui Ni 
funded by the National Natural Science Foundation of China(Grant No.82073518).
Epithelial-mesenchymal transition(EMT)is a vital pathological feature of silica-induced pulmonary fibrosis.However,whether circRNA is involved in the process remains unclear.The present study aimed to investigate the ...
关键词：SILICOSIS epithelial-mesenchymal transition circPVT1 miR-497-5p TCF3 
Prognostic Nutritional Index Associates with the Severity of Silicosis:A Study from a Tertiary Class A Prevention and Treatment Institute for Occupational Diseases in China
《Biomedical and Environmental Sciences》2024年第1期122-126,共5页HE La Gu LIANG Yun Lai YANG Lu Qi YUAN Hua Min 
supported by the scientific research project of Hunan Prevention and Treatment Institute for Occupational Diseases in 2021(Y2021-013)。
Pneumoconiosis is a group of heterogeneous fibrotic lung diseases caused by inorganic mineral dust and includes coal workers’pneumoconiosis and silicosis.Silicosis involves diffuse or nodular interstitial pulmonary f...
关键词：diagnosis LUNG diseases 
The characteristics of plasma lipids in silicosis rat models were studied based on lipid metabolomics
《China Medical Abstracts(Internal Medicine)》2023年第4期205-205,共1页何海兰 
Objective To screen the differential metabolites and metabolic pathways in silicosis model by analyzing plasma metabolomics of silicosis rats.Methods In May 2021,twenty male SD rats were randomly divided into control ...
关键词：SILICOSIS RATS LIPIDS 
Neutralization of interleukin-11 attenuates silica particles-induced pulmonary inflammation and fibrosis in vivo
《Journal of Environmental Sciences》2023年第4期772-783,共12页Jixuan Ma Yujia Xie Yiju Xu Pei Gu Yingdie Zhang Lieyang Fan Yun Zhou Haijiao Wang Ting Zhou Jintong He Dongming Wang Weihong Chen 
supported by the National Natural Science Foundation of China (Nos. 81803205 and 81872593);the China Postdoctoral Science Foundation (No. 2019T120665);the Hubei Province Key Laboratory of Occupational Hazard Identification and Control, Wuhan University of Science and Technology (No. OHIC_(2)020G01);the Fundamental Research Funds for the Central Universities (No. 2020kfy XJJS005);the Open Projects Program of Guangdong Provincial Key Laboratory of Occupational Disease Prevention and Treatment (No. 2017B030314152)。
Environmental exposure to crystalline silica particles can lead to silicosis, which is one of the most serious pulmonary interstitial fibrosis around the world. Unfortunately, the exact mechanism on silicosis is uncle...
关键词：Silica particles INFLAMMATION FIBROSIS INTERLEUKIN-11 SILICOSIS 
Application of Serum Apelin and MMP-9 in Evaluation of Silicosis and Their Correlation with Lung Function
《Agricultural Biotechnology》2023年第1期39-42,共4页Gaocai XIONG Yuanfeng YANG Jiasong LI Tingqian LIU Bingbing HE Zhuoling LIU 
Supported by Science and Technology Fund Project of Guizhou Provincial Health Commission (gzwjkj2020-1-184)。
[Objectives]This study was conducted to explore the combination of serum Apelin and MMP-9 in the assessment of silicosis and their correlation with lung function. [Methods] From January 2020 to January 2021, eight pat...
关键词：Serum Apelin MMP-9 SILICOSIS Condition assessment Pulmonary function Correlation study 
全选清除导出
共5页<12345>
检索报告 对象比较 聚类工具 使用帮助 返回顶部