云南高校图书馆联盟文献共享服务平台- RUTAECARPINE

RUTAECARPINE: 作品数：18被引量：71H指数：4; 导出分析报告; 相关领域：医药卫生更多>>; 相关作者：陈迎春刘青桑海婴陈建兴郑伟更多>>; 相关机构：北京大学中山大学上海市计划生育科学研究所国家新药筛选中心更多>>; 相关期刊：《Acta Biochimica et Biophysica Sinica》《Natural Products and Bioprospecting》《Chinese Herbal Medicines》《Chinese Journal of Integrative Medicine》更多>>; 相关基金：国家自然科学基金上海市青年科技启明星计划国家重点基础研究发展计划更多>>

Effects of Rutaecarpine on Chronic Atrophic Gastritis Through Nucleotide-binding Oligomerization Domain-like Receptors and Inflammasomes: 《World Journal of Traditional Chinese Medicine》2024年第3期303-315,共13页Yong He Xin Wang Li-Sheng Chen Lei Chang Ting-Ting He Ao-Zhe Zhang Hao-Tian Li Shi-Zhang Wei Man-Yi Jing Yan-Ling Zhao; supported by the Major Program of the National Natural Science Foundation of China (No. 82192915);the National Key Research and Development Program (No. 2018YFC1704500); Objective: Chronic atrophic gastritis(CAG) is a complex and burdensome disease. However, side effects and compliance issues cannot be ignored due to the long treatment cycle. Numerous studies have confirmed the effect...; 关键词：Chronic atrophic gastritis infiammasome nucleotide‑binding oligomerization domain‑like receptors PYROPTOSIS RUTAECARPINE

Rutaecarpine ameliorates imiquimod-induced psoriasis-like dermatitis in mice associated with alterations in the gut microbiota: 《Acta Biochimica et Biophysica Sinica》2024年第3期345-355,共11页Yongjian Li Zhengping Tan Wencan Li Zongxuan Li Guiying Zhang; This work was supported by the grant from the Natural Science Foundation of Changsha(No.kq2202410).; Psoriasis is accepted as a chronic,inflammatory,immune-mediated skin disease triggered by complex environmental and genetic factors.For a long time,disease recurrence,drug rejection,and high treatment costs have remai...; 关键词：PSORIASIS rutaecarpine(RUT) inflammatory factor gut microbiota

Discovery of novel triple targeting G–quadruplex and topoisomerase 1/2 ligands from natural products evodiamine and rutaecarpine: 《Chinese Chemical Letters》2023年第4期203-210,共8页Haibo Wang Xuexin Bai Yahui Huang Yueru Chen Guoqiang Dong Tianmiao Ou Shanchao Wu Defeng Xu Chunquan Sheng; supported by the National Natural Science Foundation of China (Nos. 22077138 to S. Wu, 81725020 to C. Sheng;81872742 to G. Dong);the National Key Research and Development Program of China (No. 2020YFA0509200 to C. Sheng);Shanghai Rising-Star Program (No. 22QA1411300 to S. Wu)。; Inspired by the indolopyridoquinazoline scaffold of natural products evodiamine and rutaecarpine, novel triple G4 and Top1/2 ligands were rationally designed and synthesized. Systematic structure–activity relationshi...; 关键词：Indolopyridoquinazoline G-QUADRUPLEX TOPOISOMERASE Structure-activity relationship Antitumor activity

Rutaecarpine attenuates monocrotaline-induced pulmonary arterial hypertension in a Sprague-Dawley rat model: 《Traditional Medicine Research》2023年第1期26-35,共10页Xiao-Wei Gong Yan-Ling Sheng Shi-Wei Kang Bo-Yun Yuan Ya-Dong Yuan; Background:Pulmonary arterial hypertension presents with obliterative remodeling of the pulmonary arteries and progressive elevation of pulmonary vascular resistance,which increase the risk of right ventricular failur...; 关键词：RUTAECARPINE pulmonary arterial hypertension inflammatory response oxidative stress vascular proliferation

Simultaneous quantification of evodiamine,rutaecarpine,and dehydroevodiamine in rat cerebrospinal fluid and cerebral nuclei after oral administration by UPLC-MS/MS被引量：2: 《Journal of Chinese Pharmaceutical Sciences》2022年第1期13-22,共10页Yanfang Yang Yinan Zhang Youbo Zhang Xiuwei Yang; National Natural Science Foundation of China(Grant No.81773865);the National Key R&D Program of China(Grant No.2018YFC1704500,2018YFC1704506)。; Evodiamine,rutaecarpine,and dehydroevodiamine have been demonstrated as the major alkaloids in the fruits of Euodia rutaecarpa,a well-known traditional Chinese medicine with central nervous system activities.To study ...; 关键词：EVODIAMINE RUTAECARPINE Dehydroevodiamine Cerebrospinal fluid Cerebral nuclei UPLC-MS/MS

TBHP-Mediated Oxidative Decarboxylative Cyclization in Water:Directand Sustainable Access to Anti-malarial Polycyclic Fused Quinazolinonesand Rutaecarpine: 《Chinese Journal of Chemistry》2020年第11期1239-1244,共6页Xingyu Chen Fei Xia Yifan Zhao Ji Ma Yue Ma Dong Zhang Lan Yang Peng Sun; Generaus financial support was from the National NaturalScience Foundation of China(Nos.21702235,81841001);the Fundamental Research Funds for the Central Public Welfare Research Institutes(Nos.ZZ13-YQ-098,ZZ10-024,ZXKT17053);the Major National Science and Technology Program of China forlnnovative Drug(No.2017ZX09101002-001-001).; of main observation and conclusion Polycylic fused quinazolinones with anti-malarial activity were synthesized through tert-butyl hydro-peroxide(TBHP)-mediated oxidative decarboxylative cyclization between commercaly ...; 关键词：strain. smoothly OXIDATIVE

Rutaecarpine Inhibits Intimal Hyperplasia in A Balloon-Injured Rat Artery Model被引量：3: 《Chinese Journal of Integrative Medicine》2018年第6期429-435,共7页XU Yang CHEN Xiu-ping ZHANG Feng HOU Hua-hua ZHANG Jing-yi LIN Shu-xian SUN An-sheng; Supported by National Natural Science Foundation of China(No.81160528);Administration of Traditional Chinese Medicine of Guizhou Province foundation,China(No.2009-79); Objective： To investigate the effect and potential mechanisms of rutaecarpine （Rut） in a rat artery balloon-injury model. Methods： The intimal hyperplasia model was established by rubbing the endothelia with a bal...; 关键词：RUTAECARPINE balloon-injury intimal hyperplasia extracellular signal-regulated kinase 2 nitric oxide

(±)-Evodiakine,A Pair of Rearranged Rutaecarpine-Type Alkaloids From Evodia rutaecarpa被引量：3: 《Natural Products and Bioprospecting》2016年第6期291-296,共6页Yan-Hong Li Yu Zhang Li-Yan Peng Xiao-Nian Li Qin-Shi Zhao Rong-Tao Li Xing-De Wu; the NSFC-Joint Foundation of Yunnan Province(No.U1502223);the National Natural Science Foundation of China(No.21402212);the Science and Technology Program of Yunnan province(No.2015FB173);the CAS“Light of West China”Program and Youth Innovation Promotion Association CAS(X.-D.Wu).; (±)-Evodiakine(1a and 1b),a pair of rearranged rutaecarpine-type alkaloids with an unprecedented 6/5/5/7/6 ring system,were isolated from the nearly ripe fruits of Evodia rutaecarpa.Separation of the enantiomers have...; 关键词：Evodia rutaecarpa (±)-Evodiakine Rutaecarpine-type alkaloids

Antitumor Activity and Theoretical Calculation of Evodiamine and Rutaecarpine: 《Chinese Journal of Structural Chemistry》2016年第8期1174-1180,共7页郭惠张拴张珂瑶朱海燕刘靖丽刘东梅王昌利苏卓; Supported by the National Natural Science Foundation of China(81001669,81373944);the Natural Science Basic Research Plan in Shaanxi Province(2016JM8028); The antitumor activities of two alkaloids, evodiamine（EVO） and rutaecarpine（RUT）, against MCF-7, SMMC-7721 and SW-1353 cells growth in vitro were investigated by MTT assay. The results showed that the anti-tumor e...; 关键词：evodiamine and rutaecarpine anticancer activity density functional theory MTT

Rutaecarpine ameliorates hyperlipidemia and hyperglycemia in fat-fed, streptozotocin-treated rats via regulating the IRS-1/PI3K/Akt and AMPK/ACC2 signaling pathways被引量：28: 《Acta Pharmacologica Sinica》2016年第4期483-496,共14页Xu-qiang NIE Huai-hong CHEN Jian-yong ZHANG Yu-jing ZHANG Jian-wen YANG Hui-jun PAN Wen-xia SONG Ferid MURAD Yu-qi HE Ka BIAN; Aim： We have shown that rutaecarpine extracted from the dried fruit of Chinese herb Evodia rutaecarpa （Juss） Benth （Wu Zhu Yu） promotes glucose consumption and anti-inflammatory cytokine expression in insulin-res...; 关键词：RUTAECARPINE metformin fat-fed streptozotocin-treated rats metabolic syndrome type 2 diabetes HYPERLIPIDEMIA insulinreceptor substrate-1 AMPK acetyI-CoA carboxylase

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