云南高校图书馆联盟文献共享服务平台- EVODIAMINE

EVODIAMINE: 作品数：23被引量：88H指数：5; 导出分析报告; 相关领域：医药卫生更多>>; 相关作者：刘奕男张翀杨力王飞吴伟更多>>; 相关机构：第二军医大学台湾大学重庆大学浙江大学城市学院更多>>; 相关期刊：《Journal of Hainan Medical University》《Bioactive Materials》《China Medical Abstracts(Internal Medicine)》《Journal of Chinese Pharmaceutical Sciences》更多>>; 相关基金：国家自然科学基金国家重点基础研究发展计划广东省自然科学基金中国博士后科学基金更多>>

Discovery of novel triple targeting G–quadruplex and topoisomerase 1/2 ligands from natural products evodiamine and rutaecarpine: 《Chinese Chemical Letters》2023年第4期203-210,共8页Haibo Wang Xuexin Bai Yahui Huang Yueru Chen Guoqiang Dong Tianmiao Ou Shanchao Wu Defeng Xu Chunquan Sheng; supported by the National Natural Science Foundation of China (Nos. 22077138 to S. Wu, 81725020 to C. Sheng;81872742 to G. Dong);the National Key Research and Development Program of China (No. 2020YFA0509200 to C. Sheng);Shanghai Rising-Star Program (No. 22QA1411300 to S. Wu)。; Inspired by the indolopyridoquinazoline scaffold of natural products evodiamine and rutaecarpine, novel triple G4 and Top1/2 ligands were rationally designed and synthesized. Systematic structure–activity relationshi...; 关键词：Indolopyridoquinazoline G-QUADRUPLEX TOPOISOMERASE Structure-activity relationship Antitumor activity

Regulatory effects of evodiamine on glucose metabolism-related factors in CT26 colorectal carcinoma-bearing mice: 《Precision Medicine Research》2022年第4期12-17,共6页Jiang-Yue Yu Kui Chen Ruo-Qin Zhao Li-Qun Wang Chao Gong Shen-Zhou Huang Yun-Juan Zheng Pei-Wen Zhu Xin-Ran Song Fang-Hua Wu; the Affiliated Fuzhou First Hospital of Fujian Medical University,the Fuzhou Science and Technology planning project(2020-WS-123).; Objective:To investigate the therapeutic effect of evodiamine(EVO)on the expression of hexokinase(HK),lactate dehydrogenase A(LDHA),and pyruvate kinase M(PKM),key enzymes of glycolysis,in the tumor-bearing mice after ...; 关键词：EVODIAMINE mouse colon cancer cells tumor-bearing mice GLYCOLYSIS HEXOKINASE lactate dehydrogenase A pyruvate kinase M

Theoretical development and mechanism research of evodiamine's antitumor effect: 《Medical Theory and Hypothesis》2022年第3期21-26,共6页Li-Ping Liu Tian-Xiang Lei De-Liang Li Feng Li Ping-Xiang Li Ke-Li Ge Cheng-Shan Ma; Shandong Key R&D Program of Shandong Province(No.2017GSF218084);Qingdao Applied Basic Research Program(No.19-6-2-31-cg).; Evodiamine(EVO),one of the bioactive components of traditional Chinese medicine,has been widely concerned for its anti-tumor properties in recent years.In this review,the anti-tumor mechanism of EVO was reviewed from ...; 关键词：EVODIAMINE ANTI-TUMOR APOPTOSIS AUTOPHAGY cancer stem cells

Simultaneous quantification of evodiamine,rutaecarpine,and dehydroevodiamine in rat cerebrospinal fluid and cerebral nuclei after oral administration by UPLC-MS/MS被引量：2: 《Journal of Chinese Pharmaceutical Sciences》2022年第1期13-22,共10页Yanfang Yang Yinan Zhang Youbo Zhang Xiuwei Yang; National Natural Science Foundation of China(Grant No.81773865);the National Key R&D Program of China(Grant No.2018YFC1704500,2018YFC1704506)。; Evodiamine,rutaecarpine,and dehydroevodiamine have been demonstrated as the major alkaloids in the fruits of Euodia rutaecarpa,a well-known traditional Chinese medicine with central nervous system activities.To study ...; 关键词：EVODIAMINE RUTAECARPINE Dehydroevodiamine Cerebrospinal fluid Cerebral nuclei UPLC-MS/MS

Effects of evodiamine on carbon tetrachloride-induced liver fibrosis mice based no modulating gut microbiota: 《China Medical Abstracts(Internal Medicine)》2021年第4期199-199,共1页MIAO Jing; Objective To access the effects of evodiamine on carbon tetrachloride(CCl_(4))-induced liver fibrosis mice and study the mechanism based on modulating gut microbiota.Methods 30 SPF male C57BL/6 mice were randomly divi...; 关键词：C57BL/6 injection PERITONEAL

Peroxidase-mimicking evodiamine/indocyanine green nanoliposomes for multimodal imaging-guided theranostics for oral squamous cell carcinoma被引量：5: 《Bioactive Materials》2021年第7期2144-2157,共14页Zheng Wei Huihui Zou Gongyuan Liu Chuanhui Song Chuanchao Tang Sheng Chen Guorong Zhang Jianchuan Ran Yufeng Wang Xiteng Yin Yu Cai Wei Han; This work was supported by Jiangsu provincial natural science foundation(BK20180136,BK20180138,BK20191121);Project of invigorating health care through science,technology and education Jiangsu provincial medical youth talent(QNRC2016121);Nanjing clinical research center for oral diseases(NO.2019060009).; Here,evodiamine(EVO)and the photosensitizer indocyanine green(ICG)were integrated into a liposomal nanoplatform for noninvasive diagnostic imaging and combinatorial therapy against oral squamous cell carcinoma(OSCC).E...; 关键词：Oral squamous cell carcinoma EVODIAMINE Peroxidase-mimicking Trimodal antitumor therapy

茱萸碱(Evodiamine)通过NF-κB信号通路发挥抗炎效果,缓解骨关节炎的发展进程: 《医用生物力学》2021年第S01期86-86,共1页高艳杨力; 国家自然科学基金项目,11532004,11832008,11902058; 目的骨关节炎(osteoarthritis,OA)是一种受NF-κB信号通路触发的炎症反应影响的退行性疾病。茱萸碱(evodiamine,Evo)是一种具有良好抗炎活性的天然药物。然而,Evo是否骨关节炎中发挥同样的功能尚不清楚。探讨Evo在OA中的抗炎作用。方法...; 关键词：骨关节炎抗炎效果软骨细胞茱萸促炎因子退行性疾病抗炎活性软骨基质

Research progress on the mechanism of evodiamine against gastrointestinal tumor: 《Journal of Hainan Medical University》2021年第10期61-66,共6页Chun-Jiao Fan Peng Huang Gui-Hua Huang Hua Qiu Xiao-Mei Zhang; National Natural Science Foundation of China(No.81660827);Huang Guihua inheritance Studio Construction Project of famous traditional Chinese Medicine of Guangxi University of traditional Chinese Medicine(No.[2017]2)。; Evodiamine is an indole quinazoline alkaloid with anti-tumor activity,which may be developed into a drug for the treatment of tumor.It was found that evodiamine could inhibit or even block the signal pathways of Wnt/...; 关键词：EVODIAMINE Anti-gastrointestinal tumor MECHANISM Cell cycle Apoptosis

A new strategy of enhancing absorptivity and safety for evodiamine: polyamidoamine derivatives modified by polyethylene glycol chain: 《Traditional Medicine Research》2021年第2期100-110,共11页Yao-Chun Gao Yuan-Sheng Lao Meng-Xue Zhang Nan Li Chen-Yang Wu Zheng-Qi Dong; This research was funded by National Major Scientific and Technological Special Project for“Significant New Drugs Development”(No.2015ZX09501005);Chinese Academy of Medical Sciences Innovation Fund for Medical Sciences(No.2016-I2M-1-012).; Background:Traditional Chinese medicine involves complex ingredients and mixtures of ingredients that often exhibit low bioavailability,and excipients are often lacking to increase the absorption-enhancing effects.Thi...; 关键词：Polyamidoamine dendrimers Polyethylene glycol Intestinal absorption enhancer BIOAVAILABILITY EVODIAMINE Fructus Evodiae

Evodiamine inhibits high-fat diet-induced colitis-associated cancer in mice through regulating the gut microbiota被引量：16: 《Journal of Integrative Medicine》2021年第1期56-65,共10页Li-qing Zhu Li Zhang Jia Zhang Guo-lin Chang Gang Liu Dan-dan Yu Xiao-min Yu Mi-sheng Zhao Bin Ye; supported by Wenzhou Science and Technology Bureau Project(to Zhu Liqing,No.Y20190088)。; Objective:High-fat diet is one of the main risk factors that disrupt the balance of gut microbiota,which eventually will induce colorectal cancer(CRC).Evodiamine(EVO)is a wildly used multifunctional traditional Chines...; 关键词：EVODIAMINE Gut microbiota Colitis-associated cancer Signal transducer and activator of transcription 3

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