supported by grants from the National Natural Science Foundation of China (No.82373174,82002466,82202907).
Photodynamic therapy is an"old"strategy for cancer therapy featuring clinical safety and rapid working,but suitable photosensitizers for colorectal cancer therapy remain lacking.This study synthesized a novel photosen...
Collaborative Innovation Program of Jiangsu Pharmaceutical Vocational College(Grant No.20239120)。
The aim of this study is to evaluate the characteristics and patterns of adverse drug reactions(ADRs)associated with antineoplastic drugs and provide insights for safer chemotherapy practices.Based on 979 ADR cases re...
supported by the Excellent Young Scientists Fund of National Natural Science Foundation of China(82022033);National Natural Science Foundation of China(81901753 and 82001820);Shanghai Rising-Star Program(19QA1406800);Shanghai Talent Development Fund(2019040);the Fundamental Research Funds for the Central Universities(22120210561);the program for Shanghai Young Top-Notch Talent.
Post-transcriptional epigenetic modifications provide numerous implications for tumor progression,metastasis and recurrence,which also pose resistances to reactive oxygen species(ROS)-based anti-tumor.Herein,we propos...
Supported by the Key Research and Development Plan Guidance Project of Heilongjiang Province(GZ20220039);Central Support for Local Universities Reform and Development Fund Talent Training Project(2020GSP16).
In this paper,the anti-tumor,anti-inflammatory,antibacterial and anti-asthma effects of isobavachalcone and their molecular mechanisms were reviewed to provide theoretical support for further research of isobavachalco...
supported by the National Natural Science Foundation of China(Nos.52173128,51973091);the Scientific Research Fund of Liaoning Provincial Education Department,China(No.LQ2020021);the Natural Science Foundation of Jiangsu Province(Youth Foundation),China(No.BK20220784).
Vascular endothelial growth factor 2(VEGFR2)plays a vital role in regulating of tumor metastasis and angiogenesis,which has emerged as one of the effective targets for clinical tumor therapy.Herein,a series of novel f...
The Contract Grant from Zhejiang Fengan Biopharmaceutical Co.,Ltd,Zhejiang Province,China。
Traditional Chinese Medicine(TCM)has been utilized in China for thousands of years to treat and prevent various diseases,with recent research highlighting microRNAs(miRNAs)in herbal decoctions as key bioactive compone...
supported by the Key Areas Research and Development Program of Guangzhou(202007020006);the National Natural Science Foundation of China(51933011,31971296,82102194,82302360);the Science and Technology Projects of Guangzhou(2023A03J0215);the Guangdong Basic Research Center of Excellence for Functional Molecular Engineering。
Enhancing the concentration of exogenous molecular drugs within the tumor microenvironment through enzyme-catalyzed polymerization presents a novel strategy for cancer therapy.Nonetheless,the optimization of the catal...
1 BACKGROUND Over the past decade,the research and development(R&D)of anti-tumor drugs in China has undergone a remarkable leap,maintaining a high level of motivation.
supported by the National Natural Science Foundation of China (Nos. 82374045, 82173985);the Jiangsu Province Leading Talent Project (No. CZ2023SLJ0302);the National Natural Science Foundation of China (No. 82173980);Jiangsu Province Key Research and Development Program for Social Development Project (No. BE2023788);the Jiangsu Clinical Innovation Center of Digestive Cancer of Traditional Chinese Medicine (No. 2021.6)。
The treatment of tumors continues to be significantly challenging. The presence of multiple modalities, including surgery, radiation, chemotherapy and immunotherapy, the therapeutic outcomes remain limited and are oft...
This work was supported by the Science and Technology Development Fund,Macao SAR(File No.:0032/2023/ITP1);the Ministry of Education Frontiers Science Centre for Precision Oncology,University of Macao(SP2023-00001-FSCPO and FHS-FSCPO/011/2023);the National Natural Science Foundation of China(82302369).
Nanomedicine-assisted sonodynamic therapy(SDT)has emerged as one of the most promising cancer therapies due to its unique advantages of high pene-tration,non-radiation,and excellent oxidative stress effect,but has alw...