ANTI-INFLAMMATION

作品数：261被引量：916H指数：15
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相关领域：医药卫生更多>>
相关作者：徐献梅张燕平李中军高小力孟祥豹更多>>
相关机构：北京大学北京中医药大学贵阳中医学院第二附属医院华中科技大学更多>>
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相关基金：国家自然科学基金中国博士后科学基金国家重点基础研究发展计划北京市自然科学基金更多>>
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IL-37 possesses both anti-inflammatory and antiviral effects against Middle East respiratory syndrome coronavirus infection
《Animal Models and Experimental Medicine》2025年第3期483-492,共10页Feifei Qi Yiwei Yan Qi Lv Mingya Liu Ming Liu Fengdi Li Ran Deng Xujian Liang Shuyue Li Guocui Mou Linlin Bao 
the National Natural Science Foundation of China,Grant/Award Number:32000358;the CAMS initiative for Innovative Medicine of China,Grant/Award Number:2021-I2M-1-035;Young Elite Scientists Sponsorship Program by CAST(YESS),Grant/Award Number:2020QNRC001。
Background:The aim was to elucidate the function of IL-37 in middle east respiratory syndrome coronavirus(MERS-CoV)infection,thereby providing a novel therapeutic strategy for managing the clinical treatment of inflam...
关键词：ANTI-INFLAMMATION interleukin-37 MERS-CoV PNEUMONIA 
Sini decoction alleviates inflammation injury after myocardial infarction through regulating arachidonic acid metabolism
《Chinese Herbal Medicines》2025年第1期148-155,共8页Cuiping Long Qian Zhou Min Xu Xin Ding Xingxing Zhang Ya Zhang Yuping Tang Guangguo Tan 
supported by the National Natural Science Foundation of China(No.82173772,82003916,82204586,81773677);Shaanxi Provincial Key Research and Development Program(No.2022ZDLSF05-06);the Open Project Program of MOE Key Laboratory of Drug Quality Control and Pharmacovigilance(No.DQCP20/21PQ07);the innovation Capability Support Program of Shaanxi(No.2020TD-041)。
Objective:Myocardial inflammation during myocardial infarction(MI)could be inhibited by regulating arachidonic acid(AA)metabolism.Recent studies demonstrated that Sini Decoction(SND)was identified to be an effective p...
关键词：ANTI-INFLAMMATION arachidonic acid metabolism pathway conditioned medium myocardial infarction Sini Decoction 
Temporal control in shell–core structured nanofilm for tracheal cartilage regeneration:synergistic optimization of anti-inflammation and chondrogenesis
《Regenerative Biomaterials》2025年第1期32-46,共15页Wen Zhao Fanglan Xu Yumei Shen Qifeng Ding Yifei Wang Leilei Liang Wufei Dai Yongbing Chen 
Funded by National Natural Science Foundation of China(82172076);Key Scientific Program of Jiangsu Provincial Health Commission(ZD2021033);Gusu Health Leading Talent Program of Suzhou(GSWS2021020);Discipline construction project of the Second Affiliated Hospital of Soochow University(XKTJXK202004);Scientific Program of Suzhou Municipal Health and Health Committee(LCZX202004);Project of Medical New Technology Assistance of the Second Affiliated Hospital of Soochow University(23ZL004 and 23ZL012).
Cartilage tissue engineering offers hope for tracheal cartilage defect repair.Establishing an anti-inflammatory microenvironment stands as a prerequisite for successful tracheal cartilage restoration,especially in imm...
关键词：temporal control core-shell structured NANOFILM tracheal cartilage regeneration ANTI-INFLAMMATION 
A tactfully designed photothermal agent collaborating with ascorbic acid for boosting maxillofacial wound healing
《National Science Review》2025年第2期238-252,共15页Yuxin Qian Yiting Gao Dong Wang Shixuan Zhang Qiuxia Luo Guogang Shan Mengmeng Lu Dingyuan Yan Ben Zhong Tang Ming Zhang 
supported by the Medical-Engineering Inter-disciplinary Research Foundation of Shenzhen University(2023YG021);the Natural Science Foundation of Jiangsu Province(BK20240513 and BK20241863).
Maxi l lofacial injuries that may cause severe functional and aesthetic damage require effective and immediate management due to continuous exposure to diverse microbial populations.Moreover,drug resistance,biofilm fo...
关键词：maxi l lofacial wound healing photothermal sterilization ANTI-INFLAMMATION 
Xanthones from Garcinia pedunculata and Garcinia nujiangensis and their anti-inflammatory activity
《Chinese Journal of Natural Medicines》2025年第2期225-233,共9页Xiaojie Fan Yufeng Jia Jiaxin Guo Jinyuan Yang Dahong Li Huiming Hua 
Ten novel xanthones,garpedunxanthones A-G(1-5,6a/6b,7a/7b) and nujiangxanthone Q(8),along with sixteen known analogs(9-24),were isolated from Garcinia pedunculata and G.nujiangensis.Their structures were elucidated th...
关键词：Garcinia pedunculata Garcinia nujiangensis XANTHONES Network pharmacology ANTI-INFLAMMATION 
Anti-tumor,Anti-inflammatory,and Antibacterial Effects of Isobavachalcone and Their Molecular Mechanisms
《Medicinal Plant》2025年第1期78-80,共3页Hongxue LIANG Wenshuang HOU Xichun HUANG Lei JIANG Chenghao JIN 
Supported by the Key Research and Development Plan Guidance Project of Heilongjiang Province(GZ20220039);Central Support for Local Universities Reform and Development Fund Talent Training Project(2020GSP16).
In this paper,the anti-tumor,anti-inflammatory,antibacterial and anti-asthma effects of isobavachalcone and their molecular mechanisms were reviewed to provide theoretical support for further research of isobavachalco...
关键词：Isobavachalcone ANTI-TUMOR ANTI-INFLAMMATION BACTERIOSTASIS ANTI-ASTHMA 
Topical adhesive spatio-temporal nanosystem co-delivering chlorin e6 and HMGB1 inhibitor glycyrrhizic acid for in situ psoriasis chemo-phototherapy
《Acta Pharmaceutica Sinica B》2025年第2期1126-1142,共17页Lijun Su Yixi Zhu Xuebo Li Di Wang Xiangyu Chen Zhen Liu Jingjing Li Chen Zhang Jinming Zhang 
supported by funding from the China Postdoctoral Science Foundation(Nos.2023T160071 and 2021M690488);Natural Science Foundation of Sichuan Province of China for Youths(No.2023NSFSC1768,China);The Science and Technology Development Fund(SKL-QRCM(UM)2023-2025,China);The State Key Laboratory of Quality Research in Chinese Medicine,University of Macao(No.SKL-QRCM-OP23020,China);The Central Guidance on Local Science and Technology Development Fund of Sichuan(23ZYZYTS0420,China);Multidisciplinary Evaluation of Southwest Characteristic TCM Resources Multidisciplinary Interdisciplinary Innovation Team(No.ZYYCXTD-D-202209,China).
Recently,photodynamic therapy(PDT)has gained considerable attention as a promising therapeutic approach for the treatment of psoriasis.Unfortunately,the activation of high mobility group box 1 protein(HMGB1)by PDT tri...
关键词：PSORIASIS Chitosan CATECHOL Spatio-temporal nanosystem Glycyrrhizic acid liposome Chemo-phototherapy Topical delivery ANTI-INFLAMMATION 
Unveiling the anti-inflammatory effects and mechanisms of LM49 in a carrageenan-induced acute inflammation model
《Journal of Chinese Pharmaceutical Sciences》2025年第1期41-54,共14页Fan Yang Rui Li Wenting Liu Jian Sun Chengxiao Zhao Xiue Feng Qingshan Li 
The National Natural Science Foundation of China(Grant No.82003770);the National Science and Technology Major Project of China(Grant No.2018ZX09711001-001-017);the Key Research and Development Plan of Shanxi Province(Grant No.202102130501005)。
This study aimed to investigate the anti-inflammatory properties and underlying molecular mechanisms of 2,4',5'-trihydroxyl-5,2'-dibromo diphenylmethanone(LM49)using a carrageenan-induced paw edema model in mice,which...
关键词：ANTI-INFLAMMATION TRANSCRIPTOMIC Molecular docking CARRAGEENAN 2 4' 5'-Trihydroxyl-5 2'-dibromo diphenylmethanone 
Tanreqing Injection Inhibits Activation of NLRP3 Inflammasome in Macrophages Infected with Influenza A Virus by Promoting Mitophagy被引量：1
《Chinese Journal of Integrative Medicine》2025年第1期19-27,共9页LIU Tian-yi HAO Yu MAO Qin ZHOU Na LIU Meng-hua WU Jun WANG Yi YANG Ming-rui 
Supported by the Innovation Team and Talents Cultivation Program of National Administration of Traditional Chinese Medicine(No.ZYYCXTD-C-202006);the Scientific and Technological Innovation Project of China Academy of Chinese Medical Sciences(No.CI2021A00601 and CI2021B017-09)。
Objective: To investigate the inhibitory effect of Tanreqing Injection(TRQ) on the activation of nucleotide-binding oligomerization domain-like receptor pyrin domain containing 3(NLRP3) inflammasome in macrophages inf...
关键词：Tanreqing Injection influenza virus ANTI-INFLAMMATION MITOPHAGY nucleotide-binding oligomerization domain-like receptor pyrin domain containing 3 inflammasome Chinese medicine 
Novel injectable adhesive hydrogel loaded with exosomes for holistic repair of hemophilic articular cartilage defect
《Bioactive Materials》2024年第12期85-111,共27页Qinfeng Yang Guihua Liu Guanghao Chen Guo Chen Keyu Chen Lei Fan Yuesheng Tu Jialan Chen Zhanjun Shi Chuan Chen Shubo Liu Geyang Deng Xiaoqian Deng Chunhan Sun Xiaoyang Li Shuofei Yang Shaowei Zheng Bin Chen 
supported by the National Natural Science Foundation of China Youth Fund(82202662);the Guangzhou Science and Technology Program(2023A04J2314);the National Natural Science Foundation of China(12,272,164);the China Postdoctoral Science Foundation(2023M741563);the Clinical Research Startup Program of Southern Medical University by High-level University Construction Funding of Guangdong Provincial Department of Education(LC2019ZD001);the Clinical Research Program of Nanfang Hospital,Southern Medical University(2019CR016);the Project of Drug Clinical Evaluate Research of Chinese Pharmaceutical Association(CPA-Z06-ZC-2021-004);the National Natural Science Foundation of China(82370497);the Medical Scientific Research Foundation of Guangdong(A2024366);Huizhou Science Technology Project Foundation(2022CZ010423);the Macao Science and Technology Development fund(FDCT(0012/2021/AMJ,003/2022/ALC,0092/2022/A2,0144/2022/A3));the Shenzhen-Hong Kong-Macao Science and Technology Fund(Category C:SGDX20220530111203020);the Foundation of Guangdong Basic and Applied Basic Research Foundation(2022A1515140151&2022A1515140189&2023A1515140045&2022A1515140071);the National Orthopaedics Key Clinical Specialty Construction Research Foundation of Huizhou Central People’s Hospital.
Hemophilic articular cartilage damage presents a significant challenge for surgeons,characterized by recurrent intraarticular bleeding,a severe inflammatory microenvironment,and limited self-repair capability of carti...
关键词：Hemophilic articular cartilage defect Adhesive hydrogel EXOSOMES ANTI-INFLAMMATION CHONDROGENESIS 
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