XANTHONES

作品数:37被引量:72H指数:5
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相关领域:医药卫生理学更多>>
相关作者:屠鹏飞姜勇郭强周雨虹杨学东更多>>
相关机构:北京大学暨南大学北京中医药大学中国医学科学院北京协和医学院更多>>
相关期刊:《American Journal of Analytical Chemistry》《Chinese Herbal Medicines》《Chinese Journal of Natural Medicines》《Acta Pharmacologica Sinica》更多>>
相关基金:国家自然科学基金国家科技支撑计划香港赛马会慈善信托基金霍英东教育基金更多>>
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Xanthones from Garcinia pedunculata and Garcinia nujiangensis and their anti-inflammatory activity
《Chinese Journal of Natural Medicines》2025年第2期225-233,共9页Xiaojie Fan Yufeng Jia Jiaxin Guo Jinyuan Yang Dahong Li Huiming Hua 
Ten novel xanthones,garpedunxanthones A-G(1-5,6a/6b,7a/7b) and nujiangxanthone Q(8),along with sixteen known analogs(9-24),were isolated from Garcinia pedunculata and G.nujiangensis.Their structures were elucidated th...
关键词:Garcinia pedunculata Garcinia nujiangensis XANTHONES Network pharmacology ANTI-INFLAMMATION 
Elodexanthones A—J, Isoprenylated Xanthone Derivatives with Diverse Skeletons and Bioactivities from Hypericum elodeoides被引量:1
《Chinese Journal of Chemistry》2022年第24期2939-2946,共8页Yanbing Mu Yaqi Li Qiji Li Wenjun Xu Yunpeng Sun Siyuan Wang Letian Cui Lingyi Kong Jun Luo 
supported by the National Natural Science Foundation of China(32170406);the“Double First-Class”University project(CPU2018GY08).
Elodexanthones A—J (1—10), two pairs of rearranged isoprenylated xanthone enantiomers with an unprecedent 6/6/5/6 tetracyclic core (1—2) along with seven new isoprenylated xanthones (3—9) and a pair of phenylpropa...
关键词:Hypericum eldeoides Isoprenylated xanthones Structure elucidation Biological activity INFLAMMATORY 
Cytotoxic 7-Methoxylated Caged Xanthones from the Twigs of Garcinia oligantha被引量:1
《Chinese Journal of Chemistry》2021年第10期2898-2910,共13页Jin-Ling Yang Wen-Wei Fu Qian Xiang Rong Wu Yue-Xun Tang Chang-Wu Zheng Yue Lu Hua Zhou Hong-Xi Xu 
sponsored partly by grants from the Three-year Development Plan Project for Traditional Chinese Medicine(No.ZY(2018-2020)-CCCX-2001-02);the Shanghai Sailing Program(No.17YF1419500)and NSFC(No.81803545);We are also grateful to NSFC-Joint Foundation of Yunnan Province(No.U1902213);the Key-Area Research;Development Program of Guangdong Province(No.2020B1111110003)for financial support.
Main observation and conclusion Nineteen unprecedented 7-methoxylated caged xanthones(1—19)were isolated from the twigs of Garcinia oligantha under the guidance of NMR spectroscopy.Their structures and absolute confi...
关键词:Garcinio oligantha Caged Xanthones Structure elucidation X-ray diffraction Tumor cell apoptosis 
Synthesis of prenylated and geranylated xanthones and their bioactivities
《Journal of Chinese Pharmaceutical Sciences》2020年第8期564-576,共13页Beidou Zhou Zihan Yu Yugui Tong Jiali Li Baocheng Huang Rongrong Wei Zhimin Weng Xin Wang Zhipeng Ruan Jian Lin Caihong Xu Jianbo Liu 
Leading Project of Fujian Provincial Department of Science and Technology(Grant No.2018Y0072)。
Nine prenylated and geranylated xanthones were synthesized in two steps with total yields ranging from 11%to 36%.All of the compounds were first reported.Then,the antitumor,anti-tyrosinase,anti-pancreatic lipase,antif...
关键词:XANTHONE Antitumor activity Anti-tyrosinase Antifungal activity Antibacterial activity 
Activity of xanthones isolated from Lomatogonium rotatum
《Asian Journal of Traditional Medicines》2020年第3期113-120,共8页Qingdi Mu Qin He Mengyuan Tan Ruoning Wang Jing Wang Chongning Lv Hang He Jincai Lu Lingyun Jia 
We thank the fourth national survey of traditional Chinese medicine resources(2018016)for funding this research.
Thirteen xanthones were isolated from L.rotatum,which were established as l,8-dihydroxy-3,4,5-trimethoxyxanthone(1);l-hydroxy-3异,8-trimethoxyxanthone(2);8-hydroxy-l,3?5-trimethoxyxaiithone(3);l-hydroxy-3,4,5-trimetho...
关键词:Lomatogonium rotatum xanthones ACTIVITY 
Antioxidant Nature Adds Further Therapeutic Value: An Updated Review on Natural Xanthones and Their Glycosides被引量:3
《Digital Chinese Medicine》2019年第3期166-192,共27页ZAFAR Salman JIAN Yu-Qing LI Bin PENG Cai-Yun CHOUDHARY Muhammad Iqbal RAHMAN Atta-ur WANG Wei 
funding support from the National Natural Science Foundation of China (No. 81673579);Hunan Province Universities 2011 Collaborative Innovation Center of Protection and Utilization of Hu-Xiang Chinese Medicine Resources;Hunan Provincial Key Laboratory of Diagnostics in Chinese Medicine
Plants have so much to offer as far as the discovery of new bioactive molecules is concerned.Among the several classes of phytochemicals,xanthones offer greater structural diversity and pharmacological value.They are ...
关键词:XANTHONES Xanthone glycosides ANTIOXIDANT Radical scavenging Xanthone dimers Xanthone trimers 
Metabolism, pharmacokinetics, and hepatic disposition of xanthones and saponins on Zhimu treatments for exploratively interpreting the discrepancy between the herbal safety and timosaponin A3-induced hepatotoxicity被引量:3
《Acta Pharmacologica Sinica》2018年第12期1923-1934,共12页Yang Xie Xu Zhou Hu Pei Ming-cang Chen Zhao-lin Sun Ya-ru Xue Xiao-ting Tian Cheng-gang Huang 
The National Natural Science Foundation of China (Nos.81030065and 81374052);National Natural Science Foundation for Young Scientistsof China (Nos.81603280and 81602998); Strategic Priority Program of Chinese Academy of Sciences(No.XDA12040203).
Timosaponin A3, a saponin in Zhimu, elicited hepatotoxicity via oxidative stress. However, the clinical medication of Zhimu has been historically regarded as safe, probably associated with the antioxidants it contains...
关键词:Zhimu TIMOSAPONIN A3 MANGIFERIN PHARMACOKINETICS METABOLISM HEPATOTOXICITY antioxidant 
Concise synthesis of xanthones by the tandem etherification——Acylation of diaryliodonium salts with salicylates
《Chinese Chemical Letters》2018年第6期985-988,共4页Gaoxiaozheng Liu Chao Wu Bifeng Chen Ru He Chao Chen 
supported by the National Natural Science Foundation of China (Nos. 21372138 and 21672120);The National Key Research and Development Program of China (No. 2016YFB0401400);the Fok Ying Tong Education Foundation of China (No. 151014);the Postdoctoral Foundation of the PekingTsinghua Joint Center for Life Sciences
An efficient synthetic method for multi-substituted xanthones was developed. The reaction of diaryliodonium salts and salicylates was employed for the preparation of the xanthones. This method proceeded through an int...
关键词:XANTHONE Diaryliodonium salts ETHERIFICATION Acylaion Multiple substituent 
Bioactive xanthones from whole plants of Gentianella acuta
《Chinese Herbal Medicines》2018年第1期99-102,共4页sheng-cai yang jing-ya ruan yan-xia liu zhi-juan ding ya-juan ni tao wang yi zhang 
supported by National Natural Science Foundation of China (81673688)
Objective: To study the constituents from the whole plants of Gentianella acuta and their biological activities.Methods: The compounds were isolated by multiple chromatographic methods and the structures of mentione...
关键词:Gentianella acuta (Michx.) Hulten intestine motility Mongolia native medicine XANTHONES 
Antioxidant xanthones and anthraquinones isolated from a marine-derived fungus Aspergillus versicolor被引量:4
《Chinese Journal of Natural Medicines》2018年第3期219-224,共6页WU Ze-Hong LIU Dong XU Ying CHEN Jian-Liang LIN Wen-Han 
supported by the Knowledge Innovation Program of Shenzhen(JCYJ20160428181415376 andJCYJ20150529153646078)
Chemical examination of an EtOAc extract of cultured Aspergillus versicolor fungus from deep-sea sediments resulted in the isolation of four xanthones, eight anthraquinones and five alkaloids, including a new xanthone...
关键词:Aspergillus versicolor XANTHONES ANTHRAQUINONES Antioxidant activity CYTOTOXICITY 
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