Ten novel xanthones,garpedunxanthones A-G(1-5,6a/6b,7a/7b) and nujiangxanthone Q(8),along with sixteen known analogs(9-24),were isolated from Garcinia pedunculata and G.nujiangensis.Their structures were elucidated th...
supported by the National Natural Science Foundation of China(32170406);the“Double First-Class”University project(CPU2018GY08).
Elodexanthones A—J (1—10), two pairs of rearranged isoprenylated xanthone enantiomers with an unprecedent 6/6/5/6 tetracyclic core (1—2) along with seven new isoprenylated xanthones (3—9) and a pair of phenylpropa...
sponsored partly by grants from the Three-year Development Plan Project for Traditional Chinese Medicine(No.ZY(2018-2020)-CCCX-2001-02);the Shanghai Sailing Program(No.17YF1419500)and NSFC(No.81803545);We are also grateful to NSFC-Joint Foundation of Yunnan Province(No.U1902213);the Key-Area Research;Development Program of Guangdong Province(No.2020B1111110003)for financial support.
Main observation and conclusion Nineteen unprecedented 7-methoxylated caged xanthones(1—19)were isolated from the twigs of Garcinia oligantha under the guidance of NMR spectroscopy.Their structures and absolute confi...
Leading Project of Fujian Provincial Department of Science and Technology(Grant No.2018Y0072)。
Nine prenylated and geranylated xanthones were synthesized in two steps with total yields ranging from 11%to 36%.All of the compounds were first reported.Then,the antitumor,anti-tyrosinase,anti-pancreatic lipase,antif...
We thank the fourth national survey of traditional Chinese medicine resources(2018016)for funding this research.
Thirteen xanthones were isolated from L.rotatum,which were established as l,8-dihydroxy-3,4,5-trimethoxyxanthone(1);l-hydroxy-3异,8-trimethoxyxanthone(2);8-hydroxy-l,3?5-trimethoxyxaiithone(3);l-hydroxy-3,4,5-trimetho...
funding support from the National Natural Science Foundation of China (No. 81673579);Hunan Province Universities 2011 Collaborative Innovation Center of Protection and Utilization of Hu-Xiang Chinese Medicine Resources;Hunan Provincial Key Laboratory of Diagnostics in Chinese Medicine
Plants have so much to offer as far as the discovery of new bioactive molecules is concerned.Among the several classes of phytochemicals,xanthones offer greater structural diversity and pharmacological value.They are ...
The National Natural Science Foundation of China (Nos.81030065and 81374052);National Natural Science Foundation for Young Scientistsof China (Nos.81603280and 81602998); Strategic Priority Program of Chinese Academy of Sciences(No.XDA12040203).
Timosaponin A3, a saponin in Zhimu, elicited hepatotoxicity via oxidative stress. However, the clinical medication of Zhimu has been historically regarded as safe, probably associated with the antioxidants it contains...
supported by the National Natural Science Foundation of China (Nos. 21372138 and 21672120);The National Key Research and Development Program of China (No. 2016YFB0401400);the Fok Ying Tong Education Foundation of China (No. 151014);the Postdoctoral Foundation of the PekingTsinghua Joint Center for Life Sciences
An efficient synthetic method for multi-substituted xanthones was developed. The reaction of diaryliodonium salts and salicylates was employed for the preparation of the xanthones. This method proceeded through an int...
supported by National Natural Science Foundation of China (81673688)
Objective: To study the constituents from the whole plants of Gentianella acuta and their biological activities.Methods: The compounds were isolated by multiple chromatographic methods and the structures of mentione...
supported by the Knowledge Innovation Program of Shenzhen(JCYJ20160428181415376 andJCYJ20150529153646078)
Chemical examination of an EtOAc extract of cultured Aspergillus versicolor fungus from deep-sea sediments resulted in the isolation of four xanthones, eight anthraquinones and five alkaloids, including a new xanthone...