XANTHONE

作品数:50被引量:121H指数:6
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相关领域:医药卫生理学更多>>
相关作者:谭红胜徐宏喜付文卫何泉华刘杰更多>>
相关机构:上海中医药大学华东师范大学广州医学院中山大学更多>>
相关期刊:《有机化学》《海峡药学》《Chinese Journal of Structural Chemistry》《药物化学》更多>>
相关基金:国家自然科学基金国家重点基础研究发展计划广西壮族自治区自然科学基金教育部留学回国人员科研启动基金更多>>
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Xanthone的生物合成研究进展
《药物生物技术》2023年第5期531-537,共7页孙兰兰 王凯旋 赵玉成 秦民坚 
[口山]酮(Xanthone)具有独特的C13(C6-C1-C6)碳骨架结构,是一种特殊的黄酮类化合物。[口山]酮结构多样的衍生物有广泛的生物活性和药理作用,具有显著的药用价值和经济价值。目前关于[口山]酮的研究主要集中在化学和药理活性方面,对于其...
关键词:[口山]酮 生物合成途径 关键酶 综述 芒果苷 植物次生代谢产物 
展萼金丝桃化学成分及其抗氧化活性研究
《药物化学》2023年第3期167-173,共7页张潘潘 周英 梁嘉俊 梁婷 刘爽 余欢 魏鑫 
目的:对展萼金丝桃(Hypericum lancasteri N. Robson)的化学成分进行分离鉴定;对其单体化合物进行抗氧化活性评价。方法:展萼金丝桃干燥地上部分经粉碎,95%甲醇回流提取得总提取物,使用硅胶、凝胶、MCI、ODS柱色谱、高效液相色谱(HPLC)...
关键词:展萼金丝桃 抗氧化活性 化学成分 DPPH XANTHONE 
Discovery of prenylated indole alkaloid and natural xanthone from cold-seep sediment derived fungus Talaromyces funiculosus SD-523
《Journal of Oceanology and Limnology》2023年第3期1152-1158,共7页Yanan WANG Xiaoming LI Fengyi LÜ Suiqun YANG Linghong MENG Bingui WANG 
Supported by the National Natural Science Foundation of China(No.U2006203);the National Natural Science Foundation of Jiangsu Province(No.BK20201211);the Senior User Project of R/V Kexue(No.KEXUE2020GZ02)。
A new prenylated indole alkaloid 11,17-epi-mangrovamide A(1),a new natural occurring product,1,7-dihydroxy-6-methyl-8-hydroxymethyl-xanthone(2),two known alkaloids,mangrovamide A(3)and mangrovamide G(4),and four known...
关键词:Talaromyces funiculosus cold seep prenylated indole alkaloid antimicrobial activity 
Biological investigation of phenyl benzoate, benzophenone, and xanthone compounds
《Journal of Chinese Pharmaceutical Sciences》2022年第10期738-745,共8页Beidou Zhou Chun Lei Xuemei Liao Hang Zhu Zhipeng Ruan Yuanyuan Fang Guifen Xu Yuli Chen 
Natural Science Foundation of Fujian Province (Grant No. 2022J011158);Putian City Science and Technology Plan Project (Grant No. 2021S2001-9);Fujian Provincial Key Laboratory of Innovative Drug Target Research (Grant No. FJ-YW-2021KF01)。
In the present study, we evaluated the antitumor, anti-tyrosinase, anti-pancreatic lipase, antibacterial, antifungal, and anti-α-glycosidase activities for all or a subset of 20 known compounds. They included 8 pheny...
关键词:Phenyl benzoate BENZOPHENONE XANTHONE ANTIBACTERIAL ANTIFUNGAL α-Glycosidase 
Chemical constituents isolated from the aerial parts of Swertia pseudochinensis and their potential neuroprotective effects被引量:2
《Acupuncture and Herbal Medicine》2021年第1期59-64,共6页Ke Xiang Qi He Yanmei Chen Dongxin Yang Yanwei Duan Hua Li Lixia Chen 
financially supported by the Liaoning Revitalization Talents Program(No.XLYC1807182);the Liaoning Province Natural Science Foundation(No.2019-MS-299).
Objective:Swertia pseudochinensis,an annual herb of the genus Swertia in the family Gentianaceae.Some constituents and extracts from the Swertia genus have been recently reported to possess neuroprotective effects,sug...
关键词:ANTHRAQUINONE Neuroprotective effect Parkinson disease Swertia pseudochinensis XANTHONE 
Synthesis of prenylated and geranylated xanthones and their bioactivities
《Journal of Chinese Pharmaceutical Sciences》2020年第8期564-576,共13页Beidou Zhou Zihan Yu Yugui Tong Jiali Li Baocheng Huang Rongrong Wei Zhimin Weng Xin Wang Zhipeng Ruan Jian Lin Caihong Xu Jianbo Liu 
Leading Project of Fujian Provincial Department of Science and Technology(Grant No.2018Y0072)。
Nine prenylated and geranylated xanthones were synthesized in two steps with total yields ranging from 11%to 36%.All of the compounds were first reported.Then,the antitumor,anti-tyrosinase,anti-pancreatic lipase,antif...
关键词:XANTHONE Antitumor activity Anti-tyrosinase Antifungal activity Antibacterial activity 
含氧取代xanthone类化合物的电喷雾质谱裂解规律研究被引量:1
《中南药学》2020年第6期953-958,共6页牟佳佳 靳超群 刘方 王丽莉 
2017年天津市教委科研计划项目(No.2017KJ135)。
目的研究从传统藏药藏茵陈植物中分离得到的12种含氧取代xanthone类化合物的质谱裂解规律。方法采用多级串联质谱(HPLC-ESI-MSn)技术对xanthone类化合物在正负离子模式下的电喷雾多级质谱进行分析。结果①xanthone苷元结构中取代基的数...
关键词:藏茵陈 含氧取代xanthone类化合物 电喷雾多级串联质谱 质谱裂解规律 
多环型Xanthone类天然产物的合成研究进展
《有机化学》2020年第3期551-562,共12页谢涛 何海兵 高栓虎 
国家自然科学基金(Nos.21971068,21772044);上海市优秀学术/技术带头人计划(No.18XD1401500);上海市科委基础研究项目(No.18JC1411303);教育部创新团队和中央高校基本科研业务费专项资金资助项目。
多环型xanthone类天然产物是一类具有高度氧化态和六环骨架结构的天然产物.目前分离得到的此类化合物主要来源于放线菌.由于这类化合物具有结构特独、广泛的抗细菌活性、一定程度的抗真菌活性以及良好的抗肿瘤活性,吸引了大量有机合成...
关键词:多环型xanthone 天然产物 全合成 
Antioxidant Nature Adds Further Therapeutic Value: An Updated Review on Natural Xanthones and Their Glycosides被引量:3
《Digital Chinese Medicine》2019年第3期166-192,共27页ZAFAR Salman JIAN Yu-Qing LI Bin PENG Cai-Yun CHOUDHARY Muhammad Iqbal RAHMAN Atta-ur WANG Wei 
funding support from the National Natural Science Foundation of China (No. 81673579);Hunan Province Universities 2011 Collaborative Innovation Center of Protection and Utilization of Hu-Xiang Chinese Medicine Resources;Hunan Provincial Key Laboratory of Diagnostics in Chinese Medicine
Plants have so much to offer as far as the discovery of new bioactive molecules is concerned.Among the several classes of phytochemicals,xanthones offer greater structural diversity and pharmacological value.They are ...
关键词:XANTHONES Xanthone glycosides ANTIOXIDANT Radical scavenging Xanthone dimers Xanthone trimers 
Diverse Polyphenols from Hypericum faberi
《Natural Products and Bioprospecting》2019年第3期215-221,共7页Xin-Wen Zhang Yan-Song Ye Fan Xia Xing-Wei Yang Gang Xu 
supported by the foundations from Kunming Institute of Botany(KIB2017001);Southeast Asia Biodiversity Research Institute(2017CASSEABRIQG003);CAS,and Yunnan Key Laboratory of Natural Medicinal Chemistry(S2017-ZZ11 and 2015-ZZ07).
Six new polyphenols with diferent isoprenylated xanthones,isoprenylated acylphloroglucinols,and chromone architectures,hyperfaberols A-F(1-6),were isolated from the whole plants of Hypericum faberi along with seven ot...
关键词:Hypericum faberi Isoprenylated xanthone Isoprenylated acylphloroglucinol CHROMONE Cytotoxicitiy 
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