MANGIFERIN

作品数:32被引量:72H指数:5
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相关领域:医药卫生更多>>
相关作者:殷悦林洁谌卫刘欣崔浩更多>>
相关机构:福建医科大学北京大学江西师范大学赣南医学院第一附属医院更多>>
相关期刊:《Asian Pacific Journal of Tropical Biomedicine》《Chinese Herbal Medicines》《Medicinal Plant》《Chinese Journal of Natural Medicines》更多>>
相关基金:国家自然科学基金广西壮族自治区自然科学基金江苏省“青蓝工程”基金国家教育部博士点基金更多>>
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Mangiferin alleviates diabetic pulmonary fibrosis in mice via inhibiting endothelial-mesenchymal transition through AMPK/FoxO3/SIRT3 axis被引量:1
《Acta Pharmacologica Sinica》2024年第5期1002-1018,共17页Ting-lv Fu Guo-rui Li Dong-hang Li Ru-yuan He Bo-hao Liu Rui Xiong Chen-zhen Xu Zi-long Lu Cong kuan Song Hong-liang Qiu Wen-jie Wang Shi-shi Zou Ke Yi Ning Li Qing Geng 
supported by the National Natural Science Foundation of China(No.82102269);the Fundamental Research Funds for the Central Universities(No.2042023kf0011).
Diabetes mellitus results in numerous complications.Diabetic pulmonary fibrosis(DPF),a late pulmonary complication of diabetes,has not attracted as much attention as diabetic nephropathy and cardiomyopathy.Mangiferin(...
关键词:diabetic pulmonary fibrosis MANGIFERIN AMPK SIRT3 endothelial-mesenchymal transition human umbilical vein endothelial cells 
Mangiferin alleviates renal infammatory injury in spontaneously hypertensive rats by inhibiting MCP-1/CCR2 signaling pathway
《Chinese Herbal Medicines》2023年第4期556-563,共8页Xiaoqin Hu Wei Zhao Jiagang Deng Zhengcai Du Xuewen Zeng Bei Zhou Erwei Hao 
supported by Natural Science Foundation of Guangxi Province (No. 2013GXNSFAA019114);Guangxi Key Laboratory of Efficacy Study on Chinese Materia Medica Project (No. 12-071-08)。
Objective: Hypertension is a low-grade infammation state of the disease and was easily complicated by kidneys’ infammatory response. Mangiferin(MGF), a pharmacologically active compound in various plants including Ma...
关键词:HYPERTENSION MANGIFERIN MCP-1/CCR2 renal inflammatory injury spontaneously hypertensive rat 
Mangiferin联合硼替佐米对Burkitt淋巴瘤恶性生物学行为的调控机制及对CXCR表达的影响
《中国实验血液学杂志》2023年第5期1394-1402,共9页严志民 刘彦权 许庆林 林洁 刘欣 朱秋平 陈鑫基 刘庭波 连晓岚 
江西省教育厅科学技术研究立项课题(GJJ2201414);江西省中医药管理局科技计划项目(2022B072);江西省卫健委科技项目(SKJP520201086-202130697)。
目的:分析芒果苷(mangiferin)联合硼替佐米对人Burkitt淋巴瘤Raji细胞增殖、侵袭、凋亡和自噬的作用及对CXC趋化因子受体家族(CXCR)表达的影响,并探究其间存在的分子机制,为Burkitt淋巴瘤基础研究与临床提供科学依据。方法:采用不同浓度...
关键词:芒果苷 硼替佐米 BURKITT淋巴瘤 恶性生物学行为 调控机制 CXC趋化因子受体 
Mangiferin抑制多发性骨髓瘤恶性生物学特性与发挥抗癌效应机制的实验研究
《中国实验血液学杂志》2023年第3期794-800,共7页刘彦权 殷悦 陈玉婷 沈建箴 唐焕文 
国家自然科学基金面上项目(82073582);广东省教育厅高校特色创新项目(2020KTSCX048);广东医科大学学科建设项目(4SG22003G、4SG21209G);广东医科大学科技创新专项计划(4SG22046G)。
目的:探讨纯中药提取物Mangiferin对多发性骨髓瘤(MM)细胞恶性生物学行为的影响,分析Mangiferin抗骨髓瘤效应的分子机制,为MM替代治疗提供实验依据。方法:不同浓度Mangiferin干预人MM细胞株U266、RPMI8226细胞后,CCK-8法检测细胞增殖,An...
关键词:多发性骨髓瘤 MANGIFERIN 恶性生物学行为 程序性细胞死亡 抗癌机制 
A review of patent literature on the regulation of glucose metabolism by six phytocompounds in the management of diabetes mellitus and its complications
《Journal of Integrative Medicine》2023年第3期226-235,共10页Anusree DasNandy Rajashri Virge Harsha V.Hegde Debprasad Chattopadhyay 
Diabetes mellitus is a chronic disease,typified by hyperglycemia resulting from failures in complex multifactorial metabolic functions,that requires life-long medication.Prolonged uncontrolled hyperglycemia leads to m...
关键词:BERBERINE CURCUMIN GINGEROL Gymnemic acid Gymnemagenin MANGIFERIN Diabetes mellitus Patents 
Antiviral activity of mangiferin from the rhizome of Anemarrhena asphodeloides against herpes simplex virus type 1
《Asian Pacific Journal of Tropical Biomedicine》2023年第3期112-120,共9页Wen-Da Wang Gang Chen 
supported by Project of Zhejiang Basic Public Benefit Research of Zhejiang Province (NO.LGF22Y145002)。
Objective:To evaluate the antiviral activity of pure compounds against herpes simplex virus type 1(HSV-1)from the rhizome of Anemarrhena asphodeloides.Methods:Bioassay-guided isolation was conducted to separate the ac...
关键词:Anemarrhena asphodeloides Herpes simplex virus Antiviral activity MANGIFERIN 
A review on valorization of different byproducts of mango(Mangifera indica L.)for functional food and human health被引量:3
《Food Bioscience》2022年第4期665-692,共28页Alok Kumar Gupta Pawan Singh Gurjar Karma Beer Alemwati Pongener S.C.Ravi Smita Singh Anil Verma Abha Singh Mamta Thakur Soubhagya Tripathy Deepak Kumar Verma 
Mango(Mangifera indica)is one of the most popular fruits in the world.During processing,the byproducts such as peel,seed and kernel are produced,which are high in bioactive components.There is a need to utilize them t...
关键词:Mango peel and kernel Nutritional composition Bioactive compounds Flavonoids MANGIFERIN Carotenoids Food utilization Biological properties 
Facile extraction of high-purity mangiferin from mango industrial wastes
《Journal of Chinese Pharmaceutical Sciences》2021年第10期831-837,共7页Chaohai Pang Hai Tian Xiaojie Guo Pan Wang Bingjun Han Xinfeng Yang 
The Key R&D projects in Hainan Province (Grant No. ZDYF2020160);the National Key Research and Development Project of China (Grant No. 2017YFF0207800);Central Public-interest Scientific Institution Basal Research Fund for Chinese Academy of Tropical Agricultural Sciences (Grant No. 1630082017001)。
In the present study, we described a novel, simple, and scalable method for isolating and purifying natural mangiferin from fresh mango leaves. An ultrasonic-assisted method was used to extract mangiferin from mango l...
关键词:Mango leaves MANGIFERIN EXTRACTION RECRYSTALLIZATION Purity analysis 
Mangiferin Promotes Bregs Level,Activates Nrf2 Antioxidant Signaling,and Inhibits Proinflammatory Cytokine Expression in Murine Splenic Mononuclear Cells In Vitro
《Current Medical Science》2021年第3期454-464,共11页Zhi-zhi QIN Jun RUAN Meng-ran LEE Kang SUN Ping CHEN Yan CHEN Mei HONG Ling-hui XIA Jun FANG Hao TANG 
the National Natural Science Foundation of China(No.81470347,No.81974003);The authors would like to thank the Department of Central Laboratory,Union Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan,China,for providing relevant experimental facilities and technical support.
Recent studies indicated that regulatory B cells(Bregs)and nuclear factor erythroid 2-related factor 2(Nrf2)antioxidant signaling pathway play important roles in the pathogenesis of chronic graft-versus-host disease(c...
关键词:MANGIFERIN regulatory B cells nuclear factor erythroid 2-related factor 2 INTERLEUKIN-10 IMMUNOMODULATION anti-inflammation 
Mangiferin inhibited neuroinflammation through regulating microglial polarization and suppressing NF-κB,NLRP3 pathway被引量:17
《Chinese Journal of Natural Medicines》2021年第2期112-119,共8页LEI Li-Yan WANG Rui-Cheng PAN Ya-Lei YUE Zheng-Gang ZHOU Rui XIE Pei TANG Zhi-Shu 
the National Natural Science Foundation of China(No.81603357);the Natural Science Basic Research Plan in Shaanxi Province of China(No.2017.Q8043);the Scientific Research Program Funded by Shaanxi Provincial Education Department(No.20JY011).
Inflammation plays important roles in the progress of neurodegenerative diseases,such as Parkinson’s disease and Alzheimer’s disease.Microglia is responsible for the homeostasis of the central nervous system(CNS),an...
关键词:MANGIFERIN Inflammation Microglial polarization NF-ΚB NLRP3 inflammasome 
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