IMMUNOMODULATION

作品数：259被引量：1340H指数：16
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相关领域：医药卫生更多>>
相关作者：龚明玉商亚珍李素婷周晓霞王宝元更多>>
相关机构：武汉大学承德医学院南京医科大学南京大学更多>>
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相关基金：国家自然科学基金中国博士后科学基金国家重点基础研究发展计划北京市自然科学基金更多>>
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In ovo delivery of carvacrol triggers expression of chemotactic factors, antimicrobial peptides and pro-inflammatory pathways in the yolk sac of broiler chicken embryos
《Journal of Animal Science and Biotechnology》2025年第2期883-894,共12页Mila M.Y.Meijer Henry van den Brand Shahram Niknafs Eugeni Roura 
support by AgriFutures Australia’s Chicken Meat Program[grant number PRJ-011584]is gratefully acknowledged.
Background Broiler chickens are most vulnerable immediately after hatching due to their immature immune systems,making them susceptible to infectious diseases.The yolk plays an important role in early immune defence b...
关键词：Antimicrobial peptides Broiler chicken CARVACROL Essential oils IMMUNOMODULATION In ovo Yolk sac 
Exploration on the Chemical Constituents and Pharmacological Effects of Korla Fragrant Pears
《Journal of Clinical and Nursing Research》2025年第4期280-285,共6页Ping Cheng Chunmei Shi Xinyu Dai Hengbo Li Cunfei Lv Mingjie Qiu Wenpin Xu 
Science and Technology Achievements Transformation Project of the Autonomous Prefecture(Project No.:202401);National College Students'Innovation and Entrepreneurship Training Program(Project Title:"Li Zhiyun·Ku Li Chun"-Pioneer in Promoting National Geographic Brand,Project Number:202513561005).
Korla fragrant pears are one of the“famous,excellent,and special”fruits in Xinjiang.They belong to the white pear variety in the genus Pyrus of the Rosaceae family.With a long-standing planting history and strong re...
关键词：Korla fragrant pears Chemical constituents ANTIOXIDATION IMMUNOMODULATION Pharmacological effects 
Review of the current clinical and preclinical evidence pertaining to the immunomodulatory effects of black seeds (Nigella sativa)
《Acupuncture and Herbal Medicine》2025年第1期46-56,共11页Rajkapoor Balasubramanian Naina Mohamed Pakkir Maideen Arun Shanmugam 
Humans and other vertebrates are safeguarded from invading pathogenic microbes by the immune system.Black seed,scientifically known as Nigella sativa,has garnered attention for its potential immunomodulatory effects i...
关键词：Black seeds IMMUNOMODULATION IMMUNOSTIMULATION IMMUNOSUPPRESSION Interferon LYMPHOCYTES Nigella sativa 
Review of Astragalus membranaceus polysaccharides:Extraction process,structural features,bioactivities and applications
《Chinese Herbal Medicines》2025年第1期56-69,共14页Hongyue Tian Lingzhuo An Pengwang Wang Xuemin Zhang Wenyuan Gao Xia Li 
supported by Innovation Team and Talents Cultivation Program of the National Administration of Traditional Chinese Medicine(No.ZYYCXTD-D-202005);Key project at central government level(No.2060302);National Natural Science Foundation of China(No.81872956);Special Project for Transformation of Scientific and Technological Achievements in Qinghai Province(No.2021-SF-150)。
Astragalus membranaceus possesses the function of enhancing immunity,protecting the liver,diuretic,anti-aging,anti-stress,anti-hypertensive,and more extensive antibacterial effects.Polysaccharides,one kind of the majo...
关键词：antidiabetic activity ANTITUMOR APPLICATIONS Astragalus membranaceus(Fisch.)Bge. Astragalus membranaceus polysaccharides extraction process IMMUNOMODULATION structure-activity relationship 
Modifying metabolic and immune hallmarks of cancer by a copper complex
《Science China Chemistry》2025年第3期1051-1066,共16页Chengyan Chu Yunhua Zhang Chengyuan Qian Xiu-Zhi Yang Yicun Shang Zijian Guo Xiaoyong Wang 
the National Natural Science Foundation of China (22377053,92153303,22293051);the Natural Science Foundation of Jiangsu Province (BK20202004)。
Metabolic adaptation of cancer cells is a key tactic for maintaining their tumorigenicity and viability in the tumor immune microenvironment(TIME).Concurrent modulation on the metabolic pathway and immune system could...
关键词：cancer hallmark copper complex cuproptosis lactate metabolism IMMUNOMODULATION 
Fetal mice dermal mesenchymal stem cells promote wound healing by inducing M2 type macrophage polarization
《World Journal of Stem Cells》2025年第2期96-104,共9页Zhen-Yu Xia Yi Wang Nian Shi Mei-Qi Lu Yun-Xiang Deng Yong-Jun Qi Xing-Lei Wang Jie Zhao Du-Yin Jiang 
National Natural Science Foundation of China,No.81873934;and Jinan Science and Technology Planning Project,No.202225065.
BACKGROUND Mesenchymal stem cells,found in various tissues,possess significant healing and immunomodulatory properties,influencing macrophage polarization,which is essential for wound repair.However,chronic wounds pre...
关键词：Fetal dermal mesenchymal stem cells Macrophage polarization Wound healing IMMUNOMODULATION M2 phenotype 
Multidimensional Role of Amino Acid Metabolism in Immune Regulation:From Molecular Mechanisms to Therapeutic Strategies
《Chemical Research in Chinese Universities》2025年第1期1-14,共14页QIN Changjuan YANG Guanqing WEI Qi XIN Hua DING Jianxun CHEN Xuesi 
supported by the National Natural Science Foundation of China(Nos.U23A20591,52273158,and 52203200);the Science and Technology Development Program of Jilin Province,China(Nos.20240101002JJ,20240404010ZP,and YDZJ202402077CXJD);the Youth Talents Promotion Project of Jilin Province,China(No.Y2023066).
Immune cells are essential components of the human immune system,playing a critical role in maintaining human health and defending against diseases.Changes in nutritional metabolism influence the activation,proliferat...
关键词：Amino acid METABOLISM Dendritic cell T cell IMMUNOMODULATION 
Microenvironment-adaptive nanodecoy synergizes bacterial eradication,inflammation alleviation,and immunomodulation in promoting biofilm-associated diabetic chronic wound healing cascade
《Aggregate》2024年第6期414-434,共21页Lei Chen Mengna Peng Wei He Xiaoli Hu Jian Xiao Linqi Shi Yong Liu Yuanfeng Li 
China Postdoctoral Science Foundation,Grant/Award Number:2022M723108;Startup Fund of Wenzhou Institute,University of Chinese Academy of Sciences,Grant/Award Numbers:WIUCASQD2021022,WIUCASQD2021019;National Natural Science Foundation of China,Grant/Award Numbers:22103088,22275043,52203184,52293383,82204940,52293380。
The presence of bacterial biofilms and the occurrence of excessive inflammatory response greatly imped the healing process of chronic wounds in diabetic patients.However,effective strategies to simultaneously address ...
关键词：BIOFILM chronic wound inflammatory cytokines reactive oxygen species synergy therapy 
Role of immune relevant factors in regenerative processes of bone tissue: a bibliometric and visualized analysis
《Biomedical Engineering Communications》2024年第4期8-19,共12页Jie Wang Li-Qing Jiang Hao-Peng Li 
Background:There is a deficiency of bibliometric and visually represented analysis in research on the immunological related variables involved in bone tissue regeneration.Using bibliometric and visual analysis,this st...
关键词：immune relevant factors MACROPHAGES macrophage-based immunomodulation macrophage polarization regenerative processes bone tissue 
Surface modification strategies to reinforce the soft tissue seal at transmucosal region of dental implants
《Bioactive Materials》2024年第12期404-432,共29页Siqi Jin Yameng Yu Ting Zhang Daping Xie Yufeng Zheng Chunming Wang Yunsong Liu Dandan Xia 
supported by the National Key Research and Development Program of China(2023YFC2412600);the National Natural Science Foundation of China(52271243,52171233,82370924);the NSFC-RFBR Joint Research Scheme(82361138575);the Beijing Nova Program(20230484459);the Beijing Natural Science Foundation(7242173);the Clinical Medicine Plus X-Young Scholars Project of Peking University;the Fundamental Research Funds for the Central Universities(PKU2024LCXQ014).
Soft tissue seal around the transmucosal region of dental implants is crucial for shielding oral bacterial invasion and guaranteeing the long-term functioning of implants.Compared with the robust periodontal tissue ba...
关键词：Surface modifications Dental implant transmucosal region Soft tissue seal ANTIBACTERIAL IMMUNOMODULATION 
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