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BERBERINE: 作品数：272被引量：1631H指数：22; 导出分析报告; 相关领域：医药卫生更多>>; 相关作者：陈宇雷帆邢东明杜力军胡珺更多>>; 相关机构：清华大学中国药科大学中国科学院西南大学更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金广东省自然科学基金中国博士后科学基金北京市自然科学基金更多>>

Mechanistic insights into the amelioration effects of diabetic cardiomyopathy by berberine:an integrated systems pharmacology study and experimental validation: 《Traditional Medicine Research》2025年第3期42-55,共14页Hui-Min Ji Wen Yang Yu Hua Yi-Xuan Sun Ao-Di Li Yue Jiang Zi-Qi Ye Min Lei Xi-Ying Guo Xiu-Fen Liu Ning-Hua Wu Huan-Bo Cheng Qing-Jie Chen; supported by the National Natural Science Foundation of China(Grant No.82270892);Natural Science Foundation of Hubei Province(Grant No.2022CFB287);Xianning City Science and Technology Plan Project(Grant No.2022ZRKX052);School projects of Hubei University of Science and Technology(Grant No.2022T01,2021WG05,2021TNB01);Hubei University of Science and Technology School-level Fund(Grant No.BK202122).; Background:Diabetic cardiomyopathy(DCM)is a type of cardiomyopathy caused by long-term diabetes,characterized by abnormal myocardial structure and function,which can lead to heart failure.Berberine(BBR),a quaternary a...; 关键词：BERBERINE APOPTOSIS integrated systems pharmacology diabetic cardiomyopathy

Berberine Hydrochloride Improves Cognitive Function and Hippocampal Antioxidant Status in Subchronic and Chronic Lead Poisoning: 《Chinese Journal of Integrative Medicine》2025年第1期49-54,共6页Fatemeh Zare Mehrjerdi Azadeh Shahrokhi Raeini Fatemeh Sadate Zebhi Zeynab Hafizi Reyhaneh Mirjalili Faezeh Afkhami Aghda; Supported by the Research Project of Shahid Sadoughi University of Medical Sciences and Health Services(No.5894)Yazd Neuroendocrine Research Center;School of Medicine,Shahid Sadoughi University of Medical Sciences and Health Services,Yazd(8915133149),Iran。; Objective: To determine the neuroprotective effects of berberine hydrochloride(BBR) against lead-induced injuries on the hippocampus of rats. Methods: Wistar rats were exposed orally to doses of 100 and 500 ppm lead a...; 关键词：lead acetate BERBERINE HIPPOCAMPUS oxidative stress Morris water maze

Synthesis and antibacterial activity of 8-ketoberberine derivatives: 《Food Quality and Safety》2024年第4期674-683,共10页Feifei Li Jingjing Wu XiyanYue Yujuan Suo Jinliang Li Fanhong Wu Yanyan Yu; supported by the Special Project of Agriculture ProduceQuality Safety Risk,Assessment(No.GJFP20220205)from the Ministry of Agriculture;Rural Affairs of the People's Republic of China and the Applied Basic Research Project of Shanghai Academy of Agricultural Sciences(China)(No.202309).; Natural berberine(BBR)exhibits good antimicrobial efficacy:however,its limited bioavailability greatly hinders its clinical application.The aim of this study is to synthesize a series of novel lipophilic C-8 substitut...; 关键词：BERBERINE alkyl ketone C-8 substitution antibacterial activity foodborne pathogens.

Network pharmacology and bioinformatics analysis identify potential therapeutic effects of berberine on colon cancer complicated with radiation enteritis: 《Acupuncture and Herbal Medicine》2024年第4期500-512,共13页Ziqiao Yan Hongyang Yu Liangliang Zhang Zebin Liao Xiangwei Ge Yuguo Wang Peiyu Tian Zhexin Ni Yongqi Dou Yue Gao; Objective:Patients with colon adenocarcinoma(COAD)who undergo radiation therapy develop radiation enteritis(RE).The predictive value of RE in COAD is yet to be established.Berberine,an active compound derived from the...; 关键词：BERBERINE Bioinformatics analysis Colon adenocarcinoma PROGNOSIS Radiation enteritis

Development of an RNA virus vector for non-transgenic genome editing in tobacco and generation of berberine bridge enzyme-like mutants with reduced nicotine content: 《aBIOTECH》2024年第4期449-464,共16页Haiying Xiang Binhuan Chen Shuo Wang Wanli Zeng Jiarui Jiang Weisong Kong Haitao Huang Qili Mi Shuang Ni Qian Gao Zhenghe Li; supported by a grant from the Natural Science Foundation of Zhejiang Province(No.LZ20C140004);FCTC grants No.110202201009(JY-09)and 110202101034(JY-11);FYCTIC Grant No.2022JY03.; Tobacco(Nicotiana tabacum)plants synthesize the psychoactive pyridine alkaloid nicotine,which has sparked growing interest in reducing nicotine levels through genome editing aiming at inactivating key biosynthetic gen...; 关键词：Eggplant mottled dwarf virus Rhabdovirus Delivery CRISPR/Cas Genome editing Berberine bridge enzyme-like TOBACCO Nicotine Alkaloid

Corrigendum:Berberine might block colorectal carcinogenesis by inhibiting the regulation of B-cell function by Veillonella parvula: 《Chinese Medical Journal》2024年第21期2602-2602,共1页; The authors declare that in the article published in vol.136,issue 22 of the Chinese Medical Journal,[1]an error was identified in the“Validation by real-time quantitative PCR(qPCR)”section.The primer sequences for ...; 关键词：INHIBITING BERBERINE COLORECTAL

Therapeutic Potential of Berberine in Type 2 Diabetes: A Short Review: 《Journal of Biomedical Science and Engineering》2024年第11期218-224,共7页Maha Aldosari Nehad Al-Shawi Noorah Saleh Al-Sowayan; Background: Type 2 Diabetes Mellitus (T2DM) is a multifactorial disease that is influenced by genetic, metabolic, and environmental factors. Genetic predisposition, obesity, low physical activity, and unhealthy diet a...; 关键词：Blood Glucose BERBERINE INSULIN Diabetes Mellitus Cancer Cells Oxidative Stress Blood Vessels

Electrospun radially oriented berberine-PHBV nanofiber dressing patches for accelerating diabetic wound healing: 《Regenerative Biomaterials》2024年第5期135-148,共14页Qiuyu Wang Sai Zhang Jiayi Jiang Shaojuan Chen Seeram Ramakrishna Wenwen Zhao Fan Yang Shaohua Wu; supported by State Key Laboratory of Bio-Fibers and Eco-Textiles of Qingdao University[TSKT202102];Startup Grant of Qingdao University;by the National Natural Science Foundation of China[22104010];Shandong Provincial Natural Science Foundation of China[ZR2021QB141];Qingchuang Science and Technology Plan of Shandong Province[2023KJ271].; A dressing patch made of radially oriented poly(3-hydroxybutyrateco-3-hydroxyvalerate)(PHBV)nanofibers was successfully manufactured with a modified electrospinning strategy.The aselectrospun PHBV radially oriented na...; 关键词：electrospinning radial alignment drug delivery wound dressing diabetic wound

Protective Effects of Berberine on Nonalcoholic Fatty Liver Disease in db/db Mice via AMPK/SIRT1 Pathway Activation: 《Current Medical Science》2024年第5期902-911,共10页Cheng CHEN Xiao-cui LIU Bin DENG; supported by grants from the National Natural Science Foundation of China(No.81803799);Hubei Province Natural Science Foundation of China(No.2022CFB092).; Objective Berberine(BBR)has emerged as a promising therapeutic agent for nonalcoholic fatty liver disease(NAFLD).This study aims to elucidate the underlying molecular mechanisms.Methods In this study,db/db mice were c...; 关键词：nonalcoholic fatty liver disease BERBERINE INFLAMMATION oxidative stress apoptosis

Berberine Inhibits Ferroptosis and Stabilizes Atherosclerotic Plaque through NRF2/SLC7A11/GPX4 Pathway: 《Chinese Journal of Integrative Medicine》2024年第10期906-916,共11页WANG Ting-ting YU Li-li ZHENG Jun-meng HAN Xin-yi JIN Bo-yuan HUA Cheng-jun CHEN Yu-shan SHANG Sha-sha LIANG Ya-zhou WANG Jian-ru; Supported by the Henan Province Science and Technology Research Project(No.182102310093)。; Objective:To investigate potential mechanisms of anti-atherosclerosis by berberine(BBR)using ApoE-/-mice.Methods:Eight 8-week-old C57BL/6J mice were used as a blank control group(normal),and 568-week-old AopE-/-mice w...; 关键词：BERBERINE ApoE−/− ferroptosis ATHEROSCLEROSIS oxidative stress NRF2/SLC7A11/GPX4 pathway

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