INSULIN

作品数:999被引量:2799H指数:21
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相关领域:医药卫生更多>>
相关作者:张强陈薇贾伟平张大卫平其能更多>>
相关机构:中国药科大学中国人民解放军总医院北京大学北京协和医院更多>>
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相关基金:国家自然科学基金国家重点基础研究发展计划国家高技术研究发展计划国家教育部博士点基金更多>>
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Decoding the nexus:branched-chain amino acids and their connection with sleep,circadian rhythms,and cardiometabolic health被引量:1
《Neural Regeneration Research》2025年第5期1350-1363,共14页Hui Li Laurent Seugnet 
supported by a grant from the French Society of Sleep Research and Medicine(to LS);The China Scholarship Council(to HL);The CNRS,INSERM,Claude Bernard University Lyon1(to LS)。
The sleep-wake cycle stands as an integrative process essential for sustaining optimal brain function and,either directly or indirectly,overall body health,encompassing metabolic and cardiovascular well-being.Given th...
关键词:branched-chain amino acids cardiovascular health circadian clock DROSOPHILA INSULIN metabolism SLEEP γ-aminobutyric acid 
Targeting Syntaxin 1A via RNA interference inhibits feeding and midgut development in Locusta migratoria
《Insect Science》2025年第2期385-397,共13页Xiaojian Liu Ya Gao Yao Li Jianzhen Zhang 
supported by the National Key R&D Program of China(2022YFD1700200);the Natural Science Foundation of Shanxi Province,China(20210302123440);the Fund for Shanxi“1331 Project”and the Graduate Education Innovation Project of Shanxi Province,China(2023SJ033).
Syntaxin 1A(Syx1A)has diverse and indispensable functions in animals.Pre-vious studies have mainly focused on the roles of Syx1A in Drosophila,and so how Syx1A operates during the development of other insects remains ...
关键词:insulin/mTOR pathway Locusta migratoria midgut development RNAi Syntaxin 1A 
Diabetes and Hypertension
《Journal of Diabetes Mellitus》2025年第1期25-39,共15页Mounika Vejendla Meghana Anagani Terry Oroszi 
Diabetes mellitus and hypertension are two of the most prevalent diseases affecting individuals across all age groups. Both conditions are linked to an increased risk of heart disease, peripheral vascular disease, str...
关键词:DIABETES METFORMIN HYPERTENSION Blood Glucose Levels INSULIN Blood Pressure 
Islet dimension and its impact on transplant outcome:A systematic review
《World Journal of Transplantation》2025年第3期212-230,共19页Sipra Rout Pravash R Mishra Appakalai N Balamurugan Praveen Kumar Ravi 
BACKGROUND Not all islet transplants desirably achieve insulin independence.This can be attributed to the microarchitecture and function of the islets influenced by their dimensions.Large islets enhance insulin secret...
关键词:Islet diameter TRANSPLANTATION Islet size Insulin-secretion VIABILITY ENGRAFTMENT Insulin independence Islet transplantation 
Insulin-induced severe thyrotoxic periodic paralysis:A case report
《World Journal of Clinical Cases》2025年第7期46-51,共6页Yan-Li Wang Jian Li 
BACKGROUND Thyrotoxic periodic paralysis(TPP)is an endocrine emergency caused by thyrotoxicosis,manifesting mainly as periodic myasthenia and hypokalemia,and posing a serious threat to the patient's health.Fatigue,str...
关键词:Thyrotoxic periodic paralysis Potassium metabolism disorders INSULIN Triggers of paralysis Case report 
Transient extreme insulin resistance in a critically ill patient:A case report
《World Journal of Clinical Cases》2025年第8期35-40,共6页Xiu-Yu Wei Hsiu-Nien Shen 
BACKGROUND Acute hyperglycemia due to insulin resistance is common in critically ill patients,typically managed with insulin infusion.However,the occurrence of transient extreme insulin resistance(EIR)requiring except...
关键词:HYPERGLYCEMIA INSULIN Insulin resistance SEPSIS Critical illness Case report 
Temperature-sensitive Micelles as Artificial Chaperones for Insulin Protection
《Chinese Journal of Polymer Science》2025年第2期350-359,共10页Jia-Wen Chen Yan Xiao Mei-Dong Lang 
financially supported by the National Natural Science Foundation of China(Nos.52273009 and 21674037).
Insulin is an essential and versatile protein taking part in the control of blood glucose levels and protein anabolism.However,under prolonged storage or high temperature stress,insulin tends to unfold and aggregate i...
关键词:TEMPERATURE-SENSITIVE INSULIN Micelles CHAPERONES 
Efficacy,safety and treatment satisfaction of transition to a regimen of insulin degludec/aspart:A pilot study
《World Journal of Diabetes》2025年第1期65-73,共9页Na Yang Lu Lv Shu-Meng Han Li-Yun He Zi-Yi Li Yu-Cheng Yang Fan Ping Ling-Ling Xu Wei Li Hua-Bing Zhang Yu-Xiu Li 
Supported by CAMS Innovation Fund for Medical Sciences,No.2023-I2M-C&T-B-043;National High Level Hospital Clinical Research Funding,No.2022-PUMCH-B-015;CAMS Innovation Fund for Medical Sciences,No.2021-1-12M-002;Beijing Municipal Natural Science Foundation,No.M22014.
BACKGROUND There is a lack of clinical evidence on the efficacy and safety of transitioning from a thrice-daily pre-mixed insulin or basal-prandial regimen to insulin degludec/aspart(IDegAsp)therapy,with insufficient ...
关键词:Insulin degludec/aspart Type 2 diabetes management Basal-bolus insulin therapy Pre-mixed insulin Diabetes treatment satisfaction questionnaire 
Exploring the links between gallstone disease, non-alcoholic fattyliver disease, and kidney stones: A path to comprehensiveprevention
《World Journal of Gastroenterology》2025年第4期176-178,共3页Jean Demarquoy 
The recent study exploring the bidirectional associations between gallstone disease,non-alcoholic fatty liver disease,and kidney stone disease highlights a critical concern in chronic disease management.Given the risi...
关键词:GALLSTONE Non-alcoholic fatty liver disease Kidney stone Shared risk factors OBESITY INSULIN Health 
Isoleucine Enriched Branched-Chain Amino Acid Supplement Improves Glucose and Insulin Sensitivity in Healthy College-Age Males but Not in Females
《Food and Nutrition Sciences》2025年第1期137-152,共16页Michael Dellogono Lyra Clark Mahdi Garelnabi Thomas A. Wilson 
Athletes often use branched-chain amino acid (BCAAs) supplements with a ratio of 2:1:1 (leucine:isoleucine:valine) for their impact on muscle building. Research suggests that by altering the ratio, an improvement in g...
关键词:ISOLEUCINE Branched-Chain Amino Acids Glucose Tolerance INSULIN 
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