DROSOPHILA

作品数:397被引量:656H指数:11
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相关领域:生物学更多>>
相关作者:戴灼华张文霞吕静陆剑曾庆韬更多>>
相关机构:北京大学中国科学院复旦大学中国农业大学更多>>
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相关基金:国家自然科学基金国家重点基础研究发展计划中国博士后科学基金广东省自然科学基金更多>>
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Exploring the role of N-acetyltransferases in diseases:a focus on N-acetyltransferase 9 in neurodegeneration
《Neural Regeneration Research》2025年第10期2862-2871,共10页Prajakta Deshpande Anuradha Venkatakrishnan Chimata Amit Singh 
supported by 1RO1EY032959-01 and RO1 supplement from NIH,Schuellein Chair Endowment Fund and STEM Catalyst Grant from the University of Dayton(to AS).
Acetyltransferases,required to transfer an acetyl group on protein are highly conserved proteins that play a crucial role in development and disease.Protein acetylation is a common post-translational modification pivo...
关键词:acetyl-coenzyme A Alzheimer’s disease animal models cell death DROSOPHILA eye human disease c-Jun N-terminal kinase signaling N-Acetyltransferases N-acetyltransferase 9 NEURODEGENERATION 
Many faces of neuronal activity manipulation in Drosophila
《Neural Regeneration Research》2025年第9期2574-2576,共3页Amber Krebs Steffen Kautzmann Christian Klämbt 
Animals exhibit complex responses to external and internal stimuli.The information is computed by interconnected neurons that express numerous ion channels,which modulate the neuronal membrane potential.How can neuron...
关键词:MANIPULATION potential. NEURONAL 
Decoding the nexus:branched-chain amino acids and their connection with sleep,circadian rhythms,and cardiometabolic health被引量:1
《Neural Regeneration Research》2025年第5期1350-1363,共14页Hui Li Laurent Seugnet 
supported by a grant from the French Society of Sleep Research and Medicine(to LS);The China Scholarship Council(to HL);The CNRS,INSERM,Claude Bernard University Lyon1(to LS)。
The sleep-wake cycle stands as an integrative process essential for sustaining optimal brain function and,either directly or indirectly,overall body health,encompassing metabolic and cardiovascular well-being.Given th...
关键词:branched-chain amino acids cardiovascular health circadian clock DROSOPHILA INSULIN metabolism SLEEP γ-aminobutyric acid 
Drosophila Larvae-Inspired Soft Crawling Robot with Multimodal Locomotion and Versatile Applications
《Research》2025年第1期35-46,共12页Qin Fang Jingyu Zhang Yinhui He Nenggan Zheng Yue Wang Rong Xiong Zhefeng Gong Haojian Lu 
supported by the Zhejiang Provincial Natural Science Foundation of China(LD22E-050007);National Natural Science Foundation of China(T2293724 and 62303407);the Key R&D Program of Zhejiang(2022C01022).
Soft crawling robots have been widely studied and applied because of their excellent environmental adaptability and flexible movement.However,most existing soft crawling robots typically exhibit a single-motion mode a...
关键词:multimodal locomotion versatile applications Drosophila larvae soft crawling robot weight soft crawling robots shape memory alloy actuators 
Calcium channels caught in peripheral glia’s tug-of-war on axon regeneration in Drosophila
《Neural Regeneration Research》2025年第2期475-476,共2页Jackson Powell Tobias Steinschaden Rose Horowitz Yuanquan Song 
Neural damage or degeneration is at the crux of many diseases,and treatment of these diseases will require the development of therapeutics to enhance and guide neural regeneration.Both intrinsic and extrinsic factors ...
关键词:DEGENERATION FIRING SYSTEM 
The gut microbiome promotes locomotion of Drosophila larvae via octopamine signaling
《Insect Science》2025年第1期277-289,共13页Juncheng Hu Ran Bi Yuxuan Luo Kaihong Wu Shan Jin Zhihua Liu Yicong Jia Chuan-Xi Mao 
upported by grants from the National Science Foundation of China(31500839 to C.M.and 81871121 to S.J.).
The gut microbiome is a key partner of animals,influencing various aspects of their physiology and behaviors.Among the diverse behaviors regulated by the gut microbiome,locomotion is vital for survival and reproductio...
关键词:Drosophila melanogaster larval locomotion MICROBIOME octopamine signaling 
Compartmentalized regulation of organelle integrity in neurodegenerative diseases:lessons from the Drosophila motor neuron
《Neural Regeneration Research》2025年第1期195-196,共2页Hyun Sung 
supported by the Merkin PNNR Center(23-DF/C2/261)(to HS).
Neurons are highly polarized,morphologically asymmetric,and functionally compartmentalized cells that contain long axons extending from the cell body.For this reason,their maintenance relies on spatiotemporal regulati...
关键词:ORGANELLE REGULATION DISTRIBUTION 
Rab1 and Syntaxin 17 regulate hematopoietic homeostasis through β-integrin trafficking in Drosophila
《Journal of Genetics and Genomics》2025年第1期51-65,共15页Fangzhou Luo Luwei Sui Ying Sun Zhixian Lai Chengcheng Zhang Gaoqun Zhang Bing Bi Shichao Yu Li Hua Jin 
supported by the National Natural Science Foundation of China(32170484 and 32300384);the Fundamental Research Funds for the Central Universities(2572022DQ07 and 2572020AW04).
Hematopoiesis is crucial for organismal health,and Drosophila serves as an effective genetic model due to conserved regulatory mechanisms with vertebrates.In larvae,hematopoiesis primarily occurs in the lymph gland,wh...
关键词:HEMATOPOIESIS Lymphgland Rab1 Syntaxin 17 β-integrin DROSOPHILA 
Drosophila Cul3 contributes to Diap2-mediated innate immune signaling for antimicrobial defense
《hLife》2025年第1期38-51,共14页Fanrui Kong Zixuan Wang Chuchu Zhang Yihua Xiao Muhammad Abdul Rehman Saeed Weini Li Akira Goto Qingshuang Cai Shanming Ji 
supported by grants from the National Natural Science Foundation of China(32100702).
The host antimicrobial immune response relies on a complex interplay of molecular mechanisms to effectively combat microbial infections.Herein,we investigate the functional role of Cullin-3(Cul3),one critical constitu...
关键词:Cullin-3(Cul3) death-associated inhibitor of apoptosis 2(Diap2) death-related ced-3/Nedd2-like caspase(Dredd)ubiquitination antimicrobial immune defense Drosophila melanogaster 
Drosophila melanogaster A rapid and reproducible method for generating germ-free
《Biophysics Reports》2024年第6期364-368,共5页An-Qi Li Sha-Sha Li Hui-Lin Li Lan-Lan Zhong Guo-Bao Tian Xin-Yuan Zhao Qiao-Ping Wang 
funded by the National Natural Science Foundation of China(31970934);the Fundamental Research Funds for the Central Universities(20ykzd18)to Q.P.W。
Microbial communities exert a profound influence on various facets of animal behavior and physiology,making the comprehension of their interactions with hosts or the environment essential.Drosophila melanogaster,a wid...
关键词:AXENIC GERM-FREE MICROBIOTA DROSOPHILA Protocol 
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