supported by 1RO1EY032959-01 and RO1 supplement from NIH,Schuellein Chair Endowment Fund and STEM Catalyst Grant from the University of Dayton(to AS).
Acetyltransferases,required to transfer an acetyl group on protein are highly conserved proteins that play a crucial role in development and disease.Protein acetylation is a common post-translational modification pivo...
Animals exhibit complex responses to external and internal stimuli.The information is computed by interconnected neurons that express numerous ion channels,which modulate the neuronal membrane potential.How can neuron...
supported by a grant from the French Society of Sleep Research and Medicine(to LS);The China Scholarship Council(to HL);The CNRS,INSERM,Claude Bernard University Lyon1(to LS)。
The sleep-wake cycle stands as an integrative process essential for sustaining optimal brain function and,either directly or indirectly,overall body health,encompassing metabolic and cardiovascular well-being.Given th...
supported by the Zhejiang Provincial Natural Science Foundation of China(LD22E-050007);National Natural Science Foundation of China(T2293724 and 62303407);the Key R&D Program of Zhejiang(2022C01022).
Soft crawling robots have been widely studied and applied because of their excellent environmental adaptability and flexible movement.However,most existing soft crawling robots typically exhibit a single-motion mode a...
Neural damage or degeneration is at the crux of many diseases,and treatment of these diseases will require the development of therapeutics to enhance and guide neural regeneration.Both intrinsic and extrinsic factors ...
upported by grants from the National Science Foundation of China(31500839 to C.M.and 81871121 to S.J.).
The gut microbiome is a key partner of animals,influencing various aspects of their physiology and behaviors.Among the diverse behaviors regulated by the gut microbiome,locomotion is vital for survival and reproductio...
supported by the Merkin PNNR Center(23-DF/C2/261)(to HS).
Neurons are highly polarized,morphologically asymmetric,and functionally compartmentalized cells that contain long axons extending from the cell body.For this reason,their maintenance relies on spatiotemporal regulati...
supported by the National Natural Science Foundation of China(32170484 and 32300384);the Fundamental Research Funds for the Central Universities(2572022DQ07 and 2572020AW04).
Hematopoiesis is crucial for organismal health,and Drosophila serves as an effective genetic model due to conserved regulatory mechanisms with vertebrates.In larvae,hematopoiesis primarily occurs in the lymph gland,wh...
supported by grants from the National Natural Science Foundation of China(32100702).
The host antimicrobial immune response relies on a complex interplay of molecular mechanisms to effectively combat microbial infections.Herein,we investigate the functional role of Cullin-3(Cul3),one critical constitu...
funded by the National Natural Science Foundation of China(31970934);the Fundamental Research Funds for the Central Universities(20ykzd18)to Q.P.W。
Microbial communities exert a profound influence on various facets of animal behavior and physiology,making the comprehension of their interactions with hosts or the environment essential.Drosophila melanogaster,a wid...