ORGANELLE

作品数：114被引量：298H指数：9
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相关领域：生物学更多>>
相关作者：林金星王幼群胡玉熹贺新强徐金森更多>>
相关机构：中国农业大学中国科学院植物研究所厦门大学中国农业科学院油料作物研究所更多>>
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相关基金：国家自然科学基金国家重点基础研究发展计划中国博士后科学基金北京市自然科学基金更多>>
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Inter-organelle communication dynamically orchestrates juvenile hormone biosynthesis and female reproduction
《National Science Review》2025年第3期64-80,共17页Shiming Zhu Fangfang Liu Xiaoyi Chen Sishi Xia Yingting Wu Wei Tang Chonghua Ren Jian Wang Sheng Li 
supported by the National Natural Science Foundation of China(32220103003 and 31930014 to S.L.,32100379 to S.M.Z.,32400402 to F.L.,32370439 and 32070500 to C.R.);the Natural Science Foundation of Guangdong Province(2023A1515010512 to S.M.Z,2021B1515020044 to C.R.);the Department of Science and Technology in Guangdong Province(2019B090905003 to S.L.);the Guangdong Basic and Ap-plied Basic Research Foundation(2020A1515110285 to S.M.Z.,2023A1515110968 to F.L.);the Shenzhen Science and Technology Program(KQTD20180411143628272 to S.L.);the China Postdoctoral Science Foundation(2023M731158 to F.L.).
Inter-organelle communication coordinates cellular homeostasis and function.Juvenile hormone(JH)is produced in the corpora allata(CA)and acts as a gonadotrophic hormone in most insects.Using transcriptomic,biochemical...
关键词：membrane receptor endoplasmic reticulum calcium signaling mitochondrial activity transcriptional regulation epigenetic regulation 
Nucleophagy repairs toxic DNA lesions
《Cell Research》2025年第3期163-164,共2页Ines Tomaskovic Cristian Prieto-Garcia Ivan Dikic 
In a recent study in Cell,Lascaux et al.revealed a novel pathway to repair toxic DNA lesions,providing a direct link between nucleophagy,a type of selective autophagy,and the resolution of damaged DNA.Autophagy is an ...
关键词：repair toxic dna lesionsproviding autophagy nucleophagy DNA repair DNA lesions DNA protein crosslinks DDR degrades recycles damaged organelles proteins 
Compartmentalized regulation of organelle integrity in neurodegenerative diseases:lessons from the Drosophila motor neuron
《Neural Regeneration Research》2025年第1期195-196,共2页Hyun Sung 
supported by the Merkin PNNR Center(23-DF/C2/261)(to HS).
Neurons are highly polarized,morphologically asymmetric,and functionally compartmentalized cells that contain long axons extending from the cell body.For this reason,their maintenance relies on spatiotemporal regulati...
关键词：ORGANELLE REGULATION DISTRIBUTION 
Recent advances in single fluorescent probes for monitoring dual organelles in two channels
《Smart Molecules》2024年第4期167-196,共30页Xiu-Zhi Yang Shankun Yao Jisong Wu Jiajie Diao Weijiang He Zijian Guo Yuncong Chen 
support from the National Natural Science Foundation of China(22122701,22477054,22293050,91953201,92153303,22377050);the Excellent Research Program of Nanjing University(ZYJH004);the Natural Science Foundation of Jiangsu Province(BK20232020).
Organelles are specialized areas where cells perform specific processes necessary for life and actively communicate with each other to keep the whole cell func-tioning.Disorders of the organelle networks are associate...
关键词：BIOIMAGING dual-color dual-targeted fluorescent probes organelle interaction 
Dark-vacuole Bodies Studying by High-resolution Label-free Microscopy Assisted with Fluorescence Technology
《Chemical Research in Chinese Universities》2024年第6期978-986,共9页LIU Xiangyu ZHANG Jinrui XU Haijiao SHAO Lina WANG Hongda 
supported by the Scientific Instrument Developing Project of the Chinese Academy of Sciences(No.ZDKYYQ20220005);the National Natural Science Foundation of China(Nos.22150003,21727816,and 21721003).
The intracellular logistics system,consisting of vesicles,plays a crucial role in cellular transport.However,there is a lack of research on the types and functions of intracellular vesicles,and new technologies are ne...
关键词：Dark-vacuole body Subcellular Organelle LABEL-FREE Fourier ptychographic microscopy(FPM) Living cell imaging 
Cryopreserved Fibroblast and Mesenchymal Stem Cells (MSCs) Being Alternative Mitochondrial Donors for Mitochondrial Organelle Transplantation (MOT)
《Journal of Biomaterials and Nanobiotechnology》2024年第4期65-77,共13页Xianpeng Jiang Brent Segal Mark S. Kindy Catherine C. Baucom 
Mitochondrial organelle transplantation (MOT) is an innovative strategy for the treatment of mitochondrial dysfunction such as cardiac ischemic reperfusion injuries, traumatic brain and spinal cord injuries, cerebral ...
关键词：Mitochondria Mitochondrial Organelle Transplantation MOT CRYOPRESERVATION Fibroblasts MSCS 
Autophagy receptor-inspired chimeras:a novel approach to facilitate the removal of protein aggregates and organelle by autophagy degradation
《Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)》2024年第12期1115-1119,共5页Liwen WANG Huimei LIU Lanfang LI 
supported by the National Natural Science Foundation of China(No.81970431);the Hunan Provincial Natural Science Foundation of China(No.2023JJ50136)。
Neurodegenerative diseases(NDDs),mainly including Huntington’s disease(HD),amyotrophic lateral sclerosis(ALS),and Alzheimer’s disease(AD),are sporadic and rare genetic disorders of the central nervous system.A key f...
关键词：HUNTINGTON DISEASES ALZHEIMER 
Label-free Super-resolution Microscopy for Long-term Monitoring the Dynamic Interactions of Cellular Organelles
《Chemical Research in Chinese Universities》2024年第6期994-1003,共10页SHAO Lina SUN Minglu ZHANG Jinrui XU Haijiao YANG Hui LI Hongru WANG Huili CUI Zongqiang LI Dayu WANG Hongda 
supported by the Scientific Instrument Developing Project of the Chinese Academy of Sciences(No.ZDKYYQ20220005);the National Natural Science Foundation of China(Nos.22150003,and 22327808);Chinese patent applications have been submitted for relevant technologies(No.202011538556.8,No.202110126844.0&No.ZL 202120587363.5).
The ideal method for imaging living cells is one that allows for long-term,label-free observation in real-time with super-resolution capabilities.Such a method would overcome the drawbacks of phototoxicity and photobl...
关键词：LABEL-FREE SUPER-RESOLUTION Fourier ptychography microscopy Long-term Cellular organelle SARS-CoV-2 virus-like particle 
Biomolecular condensates and disease pathogenesis
《Science China(Life Sciences)》2024年第9期1792-1832,共41页Ke Ruan Ge Bai Yanshan Fang Dan Li Tingting Li Xingguo Liu Boxun Lu Qing Lu Zhou Songyang Shuguo Sun Zheng Wang Xin Zhang Wen Zhou Hong Zhang 
supported by grants from the Strategic Priority Research Program of the Chinese Academy of Sciences(XDB0480000);the National Key Research and Development Program of China(2022YFA1103800,2022YFA1303100,2023YFE0210100);the National Natural Science Foundation of China(22337005,22377119,32025010,32241002,32270812,32270920,32325016,32350024,32261160376,82150003,82188101,82325016,92157202,92254301,T2325003);STI2030-Major Projects(2021ZD0202501);the Science and Technology Commission of Shanghai Municipality(2019SHZDZX02,20490712600);the Key Research Program CAS(ZDBS-ZRKJZ-TLC003);International Cooperation Program CAS(154144KYSB20200006);CAS Project for Young Scientists in Basic Research(YSBR-075);Guangdong Province Science and Technology Program(2023B1111050005,2023B1212060050);Natural Science Foundation of Anhui Province(2108085J12);Center for Advanced Interdisciplinary Science and Biomedicine of IHM(QYPY20220008);Shenzhen Talent Program(KQTD20210811090115021);Guangdong Innovative and Entrepreneurial Research Team Program(2021ZT09Y104)。
Biomolecular condensates or membraneless organelles(MLOs)formed by liquid-liquid phase separation(LLPS)divide intracellular spaces into discrete compartments for specific functions.Dysregulation of LLPS or aberrant ph...
关键词：liquid-liquid phase separation biomolecular condensate membraneless organelle 
ZW10:an emerging orchestrator of organelle dynamics during the cell division cycle
《Journal of Molecular Cell Biology》2024年第7期1-11,共11页Sm Faysal Bellah Fengrui Yang Fangyuan Xiong Zhen Dou Xuebiao Yao Xing Liu 
supported by grants from the Ministry of Science and Technology of China and the National Natural Science Foundation of China(2022YFA1303100,32090040,92254302,2022YFA0806800,W2411017,32450537,91953000,92153302,32170733,and 22177106);Plans for Major Provincial Science&Technology Projects of Anhui Province(202303a0702003);the Ministry of Education(IRT_17R102);the Strategic Priority Research Program of the Chinese Academy of Sciences(XDB19040000);the Fundamental Research Funds for the Central Universities(KB9100000007,KB9100000006,and KB9100000013).
Zeste white 10(ZW10)was first identified as a centromere/kinetochore protein encoded by the ZW10 gene in Drosophila.ZW10 guides the spindle assembly checkpoint signaling during mitotic chromosome segregation in metazo...
关键词：ZW10 KINETOCHORE membrane-bound organelle membraneless organelle MITOSIS 
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