This work was financially supported by Science and Technology Innovation Leading Plan of High-Tech Industry in Hunan Province(No.2020SK2011);The National Natural Science Foundation of China-Youth Science Fund(No.82204538);Macao Special Administrative Region Science and Technology Development Fund(No.0007/2021/AKP).
Cartilage defects are commonly observed in orthopedic clinical studies.Owing to the unique structure of cartilage tissue,current clinical treatments cannot fully address this issue.Cartilage organoids are three-dimens...
Mitochondrial organelle transplantation (MOT) is an innovative strategy for the treatment of mitochondrial dysfunction such as cardiac ischemic reperfusion injuries, traumatic brain and spinal cord injuries, cerebral ...
This review article focuses on low back pain(LBP)caused by intervertebral disc(IVD)degeneration and the need to better understand the mechanisms involved.The specific roles of cellular populations and molecular pathwa...
Supported by Major Project of Fundamental Research Funds for the Central Universities of Chengde Medical University(KY202217);Construction of Chengde Biomedical Industry Research Institute(202205B086).
[Objectives] To investigate the effect of human umbilical cord mesenchymal stem cells (hUC-MSCs) on the NOD-like receptor protein 3 (NLRP3)/cysteinyl aspartate specific proteinase (Caspase-1) pathway within the cerebr...
Liver transplantation remains the most effective treatment for end-stage liver disease(ESLD),but it is fraught with challenges such as immunosuppression,high risk and cost,and donor shortage.In recent years,stem cell ...