MICROBIOME

作品数：892被引量：3114H指数：25
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Calycosin improves atherosclerosis by reshaping the interaction between the gut microbiome and bile acid metabolism
《Food Science and Human Wellness》2025年第4期1369-1386,共18页Jiaqi Fu Donghua Yu Yuqin Liang Xin Gao Yunhe Shi Yu Wang Pingping Chen Fang Lu Shumin Liu 
supported by Heilongjiang Postdoctoral Program(ZHY2022-114);General program of Heilongjiang Province(LBHZ22251);Young Elite Scientists Sponsorship Program(2022-QNRC1-27)。
Calycosin,Astragali Radix most prominent ingredient,has drawn more attention as a result of its ability to treat atherosclerosis(AS).However,the mechanism of action has not been fully elucidated.We investigated the ef...
关键词：CALYCOSIN Atherosderosis Bile acid metabolism Gut microbiota 
Nootkatone suppresses TLR4/NF-κB/NLRP3 pathway to alleviate non-alcoholic fatty liver disease via modulating gut microbiota
《Food Science and Human Wellness》2025年第4期1398-1410,共13页Rongrong Fu Wenqing Xue Jingjie Liang Lechen Wang Min Zhang Jing Meng 
supported by grants from National Natural Science Foundation of China(82072709,81902441);Natural Science Foundation of Tianjin Municipal(23JCYBJC00850);China Postdoctoral Science Foundation(2022M712374);Tianjin“131”Innovative Talent Team Project(201926)。
Non-alcoholic fatty liver disease(NAFLD)is one of the most common chronic liver diseases worldwide.Gut microbiota and its metabolites alteration are closely related to NAFLD.Nootkatone is an edible flavorant derived f...
关键词：Nootkatone Non-alcoholic fatty liver disease Hepatic inflammation TLR4/NF-κB/NLRP3 Gut microbiome 
Integrative review of the gut microbiome’s role in pain management for orthopaedic conditions
《World Journal of Experimental Medicine》2025年第2期40-50,共11页Naveen Jeyaraman Madhan Jeyaraman Priya Dhanpal Swaminathan Ramasubramanian Arulkumar Nallakumarasamy Sathish Muthu Gabriel Silva Santos Lucas Furtado da Fonseca JoséFábio Lana 
The gut microbiome,a complex ecosystem of microorganisms,has a significant role in modulating pain,particularly within orthopaedic conditions.Its impact on immune and neurological functions is underscored by the gut-b...
关键词：Gut microbiome Pain management ORTHOPAEDICS Gut-brain axis PROBIOTICS Inflammation 
The sow vaginal and gut microbiota associated with longevity and reproductive performance
《Journal of Animal Science and Biotechnology》2025年第2期577-595,共19页Ziyu Liu Tsungcheng Tsai Bin Zuo Samantha Howe Jason EFarrar Christopher ERandolph Charles VMaxwell Jiangchao Zhao 
funded by the National Key Research and Development Program of China (2023YFE0124400);the Specific university discipline construction project (2023B10564001);grants administered by the Arkansas Biosciences Institute and the USDA;a core grant (P20GM121293, proteogenomics core)。
Background Sow longevity and reproductivity are essential in the modern swine industry.Although many studies have focused on the genetic and genomic factors for selection,little is known about the associations between...
关键词：LONGEVITY Parity Rectal microbiome Reproductive performance SOWS Vaginal microbiome 
Landscapes of gut microbiome and blood metabolomic signatures in relapsing remitting multiple sclerosis
《Science China(Life Sciences)》2025年第4期1042-1056,共15页Jinzhou Feng Shi Tang Xiaolin Yang Mengjie Zhang Zhizhong Li Shaoru Zhang Yongliang Han Yongmei Li Philippe P.Monnier Gang Yu Peng Zheng Cunjin Zhang Ke Xu Xinyue Qin 
supported by the National Science Foundation of China (81701191, 82301720);Natural Science Foundation of Chongqing (CSTB2022NSCQ-MSX0973, CSTB2023NSCQMSX0183, CSTB2023NSCQ-BHX0214);China Postdoctoral Science Foundation (2022M722384, 2023MD734128);the Joint Project of Chongqing Health Commission and Science and Technology Bureau (2020FYYX104);Chongqing Postdoctoral Special Support Foundation (2023CQBSHTB2010);Chongqing Postdoctoral Science Foundation (CSTB2023NSCQ-BHX0214);the First Affiliated Hospital of Chongqing Medical University Postdoctoral Science Foundation (CYYY-BSHPYXM-202310);CQMU Program for Youth Innovation in Future Medicine (W0168)。
Although disturbances in the gut microbiome have been implicated in multiple sclerosis(MS), little is known about the changes and interactions between the gut microbiome and blood metabolome, and how these changes aff...
关键词：relapsing remitting multiple sclerosis gut microbiota 16S rRNA gene sequence untargeted metabolomics lipid metabolism biomarker 
Review of the mechanisms of the biliary-enteric axis in the development of cholangiocarcinoma
《World Journal of Clinical Oncology》2025年第4期44-52,共9页Tian-Hao Shen Xue Yu Cheng Zhou Yu Liu Qiu-Ying Li Wei Li Ting-Hui Jiang Yong-Qiang Zhu Yan Liu 
Cholangiocarcinoma(CCA)is a particularly aggressive and challenging type of cancer,known for its poor prognosis,which is worsened by the complex interplay of various biological and environmental factors that contribut...
关键词：CHOLANGIOCARCINOMA Biliary-enteric communication of liver-gut axis MICROBIOME Bile acid metabolism Inflammatory response 
In ovo sodium butyrate administration differentially impacts growth performance, intestinal barrier function, immune response, and gut microbiota characteristics in low and high hatch-weight broilers
《Journal of Animal Science and Biotechnology》2025年第2期845-865,共21页Muhammad Zeeshan Akram Nadia Everaert Aleksandra Dunisławska 
financially supported article publication charges under the program"Regional Initiative of Excellence"(RID/SP/0017/2024/01);funding from the European Union’s Horizon 2020 research and innovation programme under the Marie Sklodowska-Curie Grant Agreement No. 955374。
Background Hatch weight(HW)affects broiler growth and low HW(LHW)often leads to suboptimal performance.Sodium butyrate(SB)has been shown to promote growth through enhanced intestinal health.This study investi-gated ho...
关键词：Broiler production Flock uniformity Gut health In ovo stimulation MICROBIOME 
Metabolomics, network pharmacology, and microbiome analyses uncover the mechanisms of the Chinese herbal formula for the improvement of meat quality in spent hens
《Journal of Animal Science and Biotechnology》2025年第2期948-964,共17页Zhihua Li Abul Kalam Azad Chengwen Meng Xiangfeng Kong Jue Gui Wenchao Lin Yadong Cui Wei Lan Qinghua He 
supported by the National Key Research and Development Project(2022YFC3400700);the City-School Cooperation Project of the Fuyang Science and Technology Special Fund undertaken by Fuyang Normal University(SXHZ2020007);the Basic Research Program of Shenzhen Municipal Government(JCYJ20200109114242138);the Special Commissioner for Rural Science and Technology of Guangdong Province(KTP20210345).
Background Meat originating from the spent hen is an important source of poultry meat production;however,multiple factors cause the decline in the meat quality of spent hens.Chinese herbs have been widely used as medi...
关键词：Cecal microbiota Chinese herbal formula Fatty acid Meat quality Network pharmacology Spent hens 
Aloin ameliorates cecal ligation and puncture-induced sepsis in mice by attenuating inflammation and modulating gut microbiota
《Food Science and Human Wellness》2025年第2期550-568,共19页Jingqian Su Jianbin Xiao Siyuan Chen Heng Zhao Xiaoni Zhang Zhihua Feng Kunsen Chen Biyun Guan Wenzhi Chen Youqiang Chen Duo Chen Qi Chen 
supported by the National Natural Science Foundation of China(81803547);the Natural Science Foundation of Fujian Province,China(2021J01204);Fujian Provincial Regional Development Project(2021N3005)。
Most Aloe species are used as new food or functional food ingredient.Even though widely known for its health benefits,the anti-inflammatory effects and underlying mechanisms of Aloin(Alo),an anthraquinone compound iso...
关键词：ALOIN Gut microbiome SEPSIS INFLAMMATION Cecal ligation and puncture 
16S amplicon sequencing and untargeted metabolomics reveal changes in rumen microorganisms and metabolic pathways involved in the reduction of methane by cordycepin被引量：1
《Journal of Integrative Agriculture》2025年第4期1310-1326,共17页Haokai Ma Dengke Liu Rui Liu Yang Li Modinat Tolani Lambo Baisheng Dai Weizheng Shen Yongli Qu Yonggen Zhang 
financially supported by the National Key Research and Development Program of China(2023YFD2000701);the Natural Science Foundation of Heilongjiang Province,China(YQ2023C011);the Key Research and Development Program of Heilongjiang Province,China(Grant no.2022ZX01A24);the Key Laboratory of Low-carbon Green Agriculture in Northeastern China,Ministry of Agriculture and Rural Affairs of China(LCGANE14)。
As a major contributor to methane production in agriculture,there is a need for a suitable methane inhibitor to reduce ruminant methane emissions and minimize the impact on the climate.This work aimed to explore the i...
关键词：CORDYCEPIN in vitro rumen fermentation rumen microbiome METABOLOME methane production 
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