CHOLANGIOCARCINOMA

作品数：529被引量：2447H指数：22
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相关领域：医药卫生更多>>
相关作者：邹声泉裘法祖刘小方叶子奇夏敏更多>>
相关机构：复旦大学山东大学华中科技大学无锡市人民医院更多>>
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相关基金：国家自然科学基金泰国研究基金国家高技术研究发展计划中国博士后科学基金更多>>
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Review of the mechanisms of the biliary-enteric axis in the development of cholangiocarcinoma
《World Journal of Clinical Oncology》2025年第4期44-52,共9页Tian-Hao Shen Xue Yu Cheng Zhou Yu Liu Qiu-Ying Li Wei Li Ting-Hui Jiang Yong-Qiang Zhu Yan Liu 
Cholangiocarcinoma(CCA)is a particularly aggressive and challenging type of cancer,known for its poor prognosis,which is worsened by the complex interplay of various biological and environmental factors that contribut...
关键词：CHOLANGIOCARCINOMA Biliary-enteric communication of liver-gut axis MICROBIOME Bile acid metabolism Inflammatory response 
Detecting plasma SHOX2, HOXA9, SEPTIN9, and RASSF1A methylation and circulating cancer cells for cholangiocarcinoma clinical diagnosis and monitoring
《World Journal of Gastrointestinal Oncology》2025年第4期210-222,共13页Jing Yu Qiu-Chen Liu Shuang-Yan Lu Shun Wang Hua Zhang 
Supported by the Medical Talents of Wuhan Health and Family Planning Commission,No.2017[51](to Yu J);the Medical Talents of Wuhan Hospital of Traditional Chinese and Western Medicine(to Yu J);the Hubei Natural Science Foundation,No.2023AFB1091;Wuhan Medical Research Project,No.WX23A36(to Yu J).
BACKGROUND Cholangiocarcinoma(CCA),also known as bile duct cancer,is a devastating malignancy primarily affecting the biliary tract.AIM To assess their performance in clinical diagnosis and monitoring of CCA,plasma me...
关键词：CHOLANGIOCARCINOMA METHYLATION Circulating cancer cells Diagnosis PROGNOSIS 
Cholangiocarcinoma:The era of liquid biopsy
《World Journal of Gastroenterology》2025年第11期14-32,共19页Evgenia Kotsifa Francesca Saffioti Vasileios K Mavroeidis 
Cholangiocarcinoma(CCA)is a highly aggressive and heterogeneous malignancy arising from the epithelial cells of the biliary tract.The limitations of the current methods in the diagnosis of CCA highlight the urgent nee...
关键词：Biliary tract cancer CHOLANGIOCARCINOMA Circulating tumour cells Cell free DNA Circulating tumour DNA Circulating RNA Biomarkers Extracellular vesicles Precision medicine 
IL-22/IL-22R1 pathway enhances cholangiocarcinoma progression via ERK1/2 activation
《World Journal of Gastrointestinal Oncology》2025年第3期246-269,共24页Jin Zhou Jing-Rui Chen Jin-Ming Li Shuang-Qing Han Xi-Yue Deng Zhong-Min Li Wen Tong Chao Wang Yi Bai Ya-Min Zhang 
National Natural Science Foundation of China,No.82372194.
BACKGROUND IL-22 plays a pivotal role in the processes of inflammation and tissue healing.,but its role in cholangiocarcinoma(CCA)remains unclear.our study explored the IL-22/IL-22R1 pathway and its impact on CCA prog...
关键词：CHOLANGIOCARCINOMA IL-22 IL-22R1 ERK1/2 Cancer progression 
High cellular prion protein expression in cholangiocarcinoma:A marker for early postoperative recurrence and unfavorable prognosis
《World Journal of Gastrointestinal Surgery》2025年第3期267-277,共11页Dong Woo Shin Yoon Ah Cho Sung-Hoon Moon Tae Hyung Kim Ji-Won Park Jung-Woo Lee Ji-Young Choe Min-Jeong Kim Sung-Eun Kim 
Supported by National Research Foundation of Korea Grant Funded by the Korea Government,No.RS-2023-00213951.
BACKGROUND The cellular prion protein(PrPC),traditionally associated with neurodegenerative disorders,plays an important role in cancer progression and metastasis by inhibiting apoptosis.AIM To investigate the influen...
关键词：CHOLANGIOCARCINOMA Cellular prion protein Liver neoplasms PROGNOSIS RECURRENCE SURVIVAL 
Research Progress of Chinese Medicine Monomers in Treatment of Cholangiocarcinoma
《Chinese Journal of Integrative Medicine》2025年第2期170-182,共13页WANG Xiang WANG Xiao-qing LUO Kai BAI He QU Jia-lin ZHANG Gui-xin 
Supported by the Grants from the National Natural Science Foundation of China(No.82174136);Dalian Medical University Intensified Program of Wellness Interdisciplinary Research Cooperation Project Team Funding(No.JCHZ2023004)。
Cholangiocarcinoma(CCA)is a malignant tumor originating from cholangiocytes.However,it remains unclear about the pathogenesis of this carcinoma,which may be related to multiple factors.Currently,CCA is mainly treated ...
关键词：CHOLANGIOCARCINOMA Chinese medicine MONOMERS ANTITUMOR signaling pathways molecular mechanisms REVIEW 
Emerging pharmaceutical therapies for targeting cholangiocarcinoma microenvironment and chemokine pathways
《BIOCELL》2024年第12期1683-1702,共20页ARMAND N.YAZDANI MICHAELA PLETSCH ABRAHAM CHORBAJIAN DAVID ZITSER VIKRANT RAI 
Mixed cholangiocarcinoma is a rare and aggressive neoplastic proliferation of biliary tract epithelial cells,accounting for up to 20%of primary liver cancers.It is the second most common primary liver malignancy with ...
关键词：CHOLANGIOCARCINOMA Chemokine pathways Tumor microenvironment Therapeutic targets 
Is 26S proteasome non-ATPase regulatory subunit 6 a potential molecular target for intrahepatic cholangiocarcinoma?
《World Journal of Hepatology》2024年第11期1219-1224,共6页Yong-Zhi Zhuang Li-Quan Tong Xue-Ying Sun 
Supported by The National Key Research and Development Program of China,No.2017YFC1308602;The Research Funds by the Fifth Affiliated Hospital of Harbin Medical University,No.2022-002 and No.2023-001.
In this editorial we comment on the article by Tang et al published in the recent issue of World Journal of Hepatology.Drug therapy of intrahepatic cholangiocarcinoma(iCCA)poses an enormous challenge since only a smal...
关键词：CHOLANGIOCARCINOMA 26S proteasome non-ATPase regulatory subunit 6 Molecular targeted therapies Proteasome inhibitors Clustered regularly interspaced short palindromic repeat 
Journey to diagnosis:An unfinished exploration of IgG4-related sclerosing cholangitis
《World Journal of Clinical Cases》2024年第33期6608-6612,共5页Ming-Xing Liang Ya Chen Ya He Yi-Huai He 
Supported by The Science and Technology Research Foundation of Guizhou Province,and Zunyi City,No.QKHJC-ZK(2022)YB642,No.ZSKH·HZ(2022)344,and No.gzwjkj2021-071;The WBE Liver Fibrosis Foundation,No.CFHPC2025028;The Beijing Gandan Phase Mutual Public Welfare Fund for Artificial Liver Project,No.iGandanF-1082024-Rgg018.
IgG4-related sclerosing cholangitis(IgG4-SC)is an inflammatory disease that leads to bile duct stricture,characterized by the infiltration of IgG4-positive plasma cells into the bile duct wall,thickening of the bile d...
关键词：Isolated IgG4-associated sclerosing cholangitis CHOLANGIOCARCINOMA Autoimmune pancreatitis IgG4-related diseases Diagnosis and differential diagnosis 
Elevated ETV4 expression in cholangiocarcinoma is linked to poor prognosis and may guide targeted therapies
《World Journal of Gastrointestinal Oncology》2024年第11期4528-4531,共4页Uchenna E Okpete Haewon Byeon 
Cholangiocarcinoma(CCA),a highly aggressive bile duct cancer,is associated with late-stage diagnosis and limited treatment options,leading to poor patient outcomes.Early detection and personalized treatment strategies...
关键词：Prognostic biomarkers CHOLANGIOCARCINOMA Survival rates ETV4 expression PEA3 subfamily Precision medicine Targeted therapy 
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