METABOLOME

作品数：200被引量：397H指数：10
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Multi-omics reveals the associations among the fecal metabolome,intestinal bacteria,and serum indicators in patients with hepatocellular carcinoma
《World Journal of Gastroenterology》2025年第15期109-130,共22页Jing Feng Jun-Ping Wang Jian-Ran Hu Ping Li Pin Lv Hu-Cheng He Xiao-Wei Cheng Zheng Cao Jia-Jing Han Qiang Wang Qian Su Li-Xin Liu 
Supported by the Department of Science and Technology of Shanxi Province,No.20210302124369;the Health Commission of Shanxi Province,No.2021116;Shanxi Administration of Traditional Chinese Medicine,No.2024ZYY2C054.
BACKGROUND Hepatocellular carcinoma(HCC),the predominant form of primary liver cancer,is a key contributor to cancer-related deaths globally.However,HCC diagnosis solely based on blood biochemical markers lacks both s...
关键词：Hepatocellular carcinoma Fecal metabolomics Intestinal bacteria Correlation analysis Non-targeted liquid chromatography-mass spectrometry 
Integration of transcriptome and metabolome reveals regulatory mechanisms of volatile flavor formation during tomato fruit ripening
《Horticultural Plant Journal》2025年第2期680-692,共13页Zhiqiang Liu Jianxin Wu Licai Wang Xiaonan Lu Golam Jalal Ahammed Xiaolan Zhang Xia Cui Haijing Wang 
supported by the National Natural Science Foundation of China(Grant Nos.32120103010,32002050);Beijing Joint Research Program for Germplasm Innovation and New Variety Breeding(Grant No.G20220628003-03);the Science and Technology Innovation Program of the Chinese Academy of Agricultural Sciences。
Tomato is an important economic crop all over the world.Volatile flavors in tomato fruit are key factors influencing consumer liking and commercial quality.However,the regulatory mechanism controlling the volatile fla...
关键词：TOMATO Volatile flavor TRANSCRIPTOME Transcription factor CO-EXPRESSION 
Metabolome and RNA-seq reveal discrepant metabolism and secretory metabolism profile in skeletal muscle between obese and lean pigs at different ages
《Science China(Life Sciences)》2025年第4期1102-1117,共16页Liu Guo Junfei Xu Wenyue Zhou Sisi Chen Hanjing Shi Mengmeng Han Zekun Yang Yehui Duan Weijun Pang Yulong Yin Fengna Li 
supported by the National Natural Science Foundation of China(31972582);the STI 2030-Major Project(2023ZD04072);the Major Project of Changsha City(kh2401015);the Science and Technology Innovation Program of Hunan Province(2021RC4039);the Key Research and Development Program of Hunan Province(2022NK2026);the Youth Innovation Promotion Association CAS(Y202079);China Agriculture Research System of MOF and MARA(CARS-35)。
Metabolites and metabolism-related gene expression profiles in skeletal muscle change dramatically under obesity,aging and metabolic disease.Since obese and lean pigs are ideal models for metabolic research.Here,we co...
关键词：skeletal muscle METABOLOME transcriptome biomarker metabolite intercellular communication lipid deposition pig model 
Prevent effects of soybean meal peptides in acute alcoholic liver injury based on gut microbiota and metabolome alteration
《Food Science and Human Wellness》2025年第2期525-535,共11页Jingbo Liu Shengrao Li Qi Yang Siwen Lyu Xuanting Liu Zhiyang Du Xiaomin Shang Ting Zhang 
funded by the National Key R&D Program of China(2022YFD2101002);Jilin Province Science and Technology Youth Talent Support Project(QT202021);Fundamental Research Funds for the Central Universities。
This study investigated the preventive effects of soybean meal peptides(SPs)and their purification peptides(GTYW)on acute alcoholic liver injury.We combined the gut microbiota,metabolites,liver inflammation,and oxidat...
关键词：Soybean meal peptides Acute alcoholic liver injury Gut microbiota METABOLITES 
16S amplicon sequencing and untargeted metabolomics reveal changes in rumen microorganisms and metabolic pathways involved in the reduction of methane by cordycepin被引量：1
《Journal of Integrative Agriculture》2025年第4期1310-1326,共17页Haokai Ma Dengke Liu Rui Liu Yang Li Modinat Tolani Lambo Baisheng Dai Weizheng Shen Yongli Qu Yonggen Zhang 
financially supported by the National Key Research and Development Program of China(2023YFD2000701);the Natural Science Foundation of Heilongjiang Province,China(YQ2023C011);the Key Research and Development Program of Heilongjiang Province,China(Grant no.2022ZX01A24);the Key Laboratory of Low-carbon Green Agriculture in Northeastern China,Ministry of Agriculture and Rural Affairs of China(LCGANE14)。
As a major contributor to methane production in agriculture,there is a need for a suitable methane inhibitor to reduce ruminant methane emissions and minimize the impact on the climate.This work aimed to explore the i...
关键词：CORDYCEPIN in vitro rumen fermentation rumen microbiome METABOLOME methane production 
Reprogramming the Metabolome of Centella asiatica (L.) Urban Callus: Profiling of Newly Synthesized Cryptic Anthocyanins Triggered by LED Light Exposure
《Phyton-International Journal of Experimental Botany》2025年第4期1269-1286,共18页Claude Y.Hamany Djande Paul A.Steenkamp Ian A.Dubery 
Centella asiatica L.,a medicinal herb,has attracted substantial interest in research as well as commercial domains due to its bioactive compounds which include the pentacyclic triterpenoid centellosides,and in additio...
关键词：Anthocyanins CALLUS Centella asiatica CRYPTIC FLAVONOIDS liquid chromatography mass spectrometry REPROGRAMMING 
Bacillus atrophaeus DX-9 biocontrol against potato common scab involves significant changes in the soil microbiome and metabolome
《aBIOTECH》2025年第1期33-49,共17页Jingjing Cao Yue Ma Jing Fu Zhiqin Wang Yonglong Zhao Naiqin Zhong Pan Zhao 
supported by the Inner Mongolia Autonomous Region Key Technology Tackling Programmed(Grant number:2021GG0300);by Hebei Science and Technology Major Project(22287501Z);by the Strategic Priority Research Program of the Chinese Academy of Sciences(Grant number:XDA28030202-3,XDA24020104).
Potato common scab(CS)is a worldwide disease,caused by Streptomyces spp.,and its presence reduces the market value of potatoes.A nontoxic and potentially effective approach in many control strategies is the use of ant...
关键词：Bacillus atrophaeus Solanum tuberosum BIOCONTROL Common scab Soil properties Microbial community 
Metabolome and transcriptome association study reveals biosynthesis of specialized benzylisoquinoline alkaloids in Phellodendron amurense
《Chinese Herbal Medicines》2025年第1期178-188,共11页Tingxia Liu Wanran Zhang Sijia Wang Ya Tian Yifan Wang Ranran Gao Shilin Chen Wei Sun Wei Ma Zhichao Xu 
funded by grants from the National Key Research and Development Project“research and demonstration of collection,screening,and breeding technology of ginseng and other genuine medicinal materials”(No.2021YFD1600901);National Natural Science Foundation of China(No.82274037);Heilongjiang Touyan Innovation Team Program(No.HLJTYTP2019001)。
Objective:Benzylisoquinoline alkaloids(BIAs)have pharmacological functions and clinical use.BIAs are mainly distributed in plant species across the order Ranunculales and the genus Phellodendron from Sapindales.The BI...
关键词：benzylisoquinoline alkaloids BIOSYNTHESIS evolution norcoclaurine synthase Phellodendron amurense Rupr 
Modulation of gut microbiota and serum metabolome by Apostichopus japonicus derived oligopeptide in high-fructose diet-induced hyperuricemia in mice
《Food Science and Human Wellness》2025年第1期161-174,共14页Jun Zhou Ziyan Wang Zhixuan Zhang Jiaojiao Han Ying Feng Jing Zhang Zhen Zhang Ye Li Tinghong Ming Chenyang Lu Rixin Wang Xiurong Su 
sponsored by the One Health Interdisciplinary Research Project,Ningbo University,Open Fund of Key Laboratory of Aquacultural Biotechnology Ministry of Education in Ningbo University,and K.C.Wong Magna Fund of Ningbo University;the National Natural Science Foundation China(32270115);National Key R&D Program of China(2018YFD0901102);Fundamental Research Funds for the Provincial Universities of Zhejiang(SJLY2021015)。
Fructose consumption has risen dramatically in recent decades due to the use of sucrose and high fructose corn syrup in beverages and processed foods,contributing to rising rates of hyperuricemia.The purpose of this e...
关键词：FRUCTOSE HYPERURICAEMIA OLIGOPEPTIDE Gut microbiota Serum metabolomics 
Identification of transcription factors contributing to vitamin C synthesis during Rosa roxburghii fruit development by integrating transcriptomics and metabolomics
《Horticultural Plant Journal》2025年第1期123-132,共10页Liyao Su Tian Zhang Zong-Ming(Max)Cheng 
supported in part by the Priority Academic Program Development of Jiangsu Higher Education Institutions and the State Key Laboratory of Crop Genetics and Germplasm Enhancement (Grant No. ZW201813);supported by the high-performance computing platform at the Bioinformatics Center of Nanjing Agricultural University。
Ascorbic acid, also referred to as vitamin C(Vc), is an important nutrient found in fruits and vegetables that promotes produce quality and human health. Rosa roxburghii is an underutilized natural fruit that contains...
关键词：Rosa roxburghii Vitamin C WGCNA TRANSCRIPTOME METABOLOME 
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