云南高校图书馆联盟文献共享服务平台- REPROGRAMMING

REPROGRAMMING: 作品数：476被引量：1598H指数：16; 导出分析报告; 相关领域：医药卫生生物学更多>>; 相关作者：颉伟张志人王建斌高平高平更多>>; 相关机构：中国科学院华中农业大学中国科学院大学中国人民解放军空军军医大学第一附属医院更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金国家重点基础研究发展计划中国博士后科学基金广东省自然科学基金更多>>

Metabolic reprogramming of astrocytes:Emerging roles of lactate: 《Neural Regeneration Research》2026年第2期421-432,共12页Zeyu Liu Yijian Guo Ying Zhang Yulei Gao Bin Ning; supported by the National Natural Science Foundation of China,Nos.82071383,82371392(to BN);the Natural Science Foundation of Shandong Province of China(Key Project),No.ZR2020KH007(to BN);“Taishan Scholar Distinguished Expert Program”of Shandong Province,No.tstp20231257(to BN);Health Commission Science and Technology Plan Project of Jinan,No.2023-1-8(to YZ).; Lactate serves as a key energy metabolite in the central nervous system,facilitating essential brain functions,including energy supply,signaling,and epigenetic modulation.Moreover,it links epigenetic modifications wit...; 关键词：ASTROCYTE epigenetic modifications inflammation LACTATE lactylation METABOLIC PLASTICITY regeneration treatment

Reprogramming induced neurons from olfactory ensheathing glial cells: A feasible approach for spinal cord injury repair: 《Neural Regeneration Research》2026年第1期296-297,共2页Javier Sierra María Portela-Lomba Diana Simón M.Teresa Moreno-Flores; financially supported by Ministerio de Ciencia e Innovación projects SAF2017-82736-C2-1-R to MTMF;in Universidad Autónoma de Madrid and by Fundación Universidad Francisco de Vitoria to JS;a predoctoral scholarship from Fundación Universidad Francisco de Vitoria;financial support from a 6-month contract from Universidad Autónoma de Madrid;a 3-month contract from the School of Medicine of Universidad Francisco de Vitoria。; Every year, around the world, between 250,000 and 500,000 people suffer a spinal cord injury(SCI). SCI is a devastating medical condition that arises from trauma or disease-induced damage to the spinal cord, disruptin...; 关键词：INJURY feasible PROGRAMMING

Neurocircuit regeneration by extracellular matrix reprogramming: 《Neural Regeneration Research》2025年第8期2300-2301,共2页Shengzhang Su Ian N.Levasseur Kimberly M.Alonge; supported by National Institute on Aging(NIH-NIA)R21 AG074152(to KMA);National Institute of Allergy and Infectious Diseases(NIAID)grant DP2 AI171150(to KMA);Department of Defense(DoD)grant AZ210089(to KMA)。; The brain's extracellular matrix(ECM),which is comprised of protein and glycosaminoglycan(GAG)scaffolds,constitutes 20%-40% of the human brain and is considered one of the largest influencers on brain cell functioning...; 关键词：MATRIX PROGRAMMING

Characteristic changes in astrocyte properties during astrocyte-to-neuron conversion induced by NeuroD1/Ascl1/Dlx2: 《Neural Regeneration Research》2025年第6期1801-1815,共15页Qing He Zhen Wang Yuchen Wang Mengjie Zhu Zhile Liang Kanghong Zhang Yuge Xu Gong Chen; supported by the Key Project of Guangzhou City,No.202206060002;Science and Technology Project of Guangdong Province,No.2018B030332001;Guangdong Provincial Pearl River Project,No.2021ZT09Y552 (all to GC)。; Direct in vivo conversion of astrocytes into functional new neurons induced by neural transcription factors has been recognized as a potential new therapeutic intervention for neural injury and degenerative disorders....; 关键词：AQUAPORIN-4 Ascl1 ASTROCYTE cortex Dlx2 gap junction glia-to-neuron conversion neural regeneration NeuroD1 REPROGRAMMING

Role of PFKM lactylation in glycolysis regulation in endometrial cancer cells: 《Genes & Diseases》2025年第3期27-30,共4页Bin Wang Jian Ma Di Yang; supported by the National Natural Science Foundation of China(No.82203469);the Liaoning Province Joint Fund General Project(China)(No.2023-MSLH-166).; The incidence of endometrial cancer(EC)is increasing,particularly in high-risk cases with poor prognosis.1 Reprogramming glucose metabolism is the main feature of energy metabolism in EC cells,resulting in substantial...; 关键词：lactic acid PFKM lactylation endometrial cancer ec reprogramming glucose metabolism glycolysis regulation metabolic process tumor cells modifying key proteins

Glia-to-neuron reprogramming to the rescue?: 《Neural Regeneration Research》2025年第5期1395-1396,共2页Jack W.Hickmott Cindi M.Morshead; supported by Canada First Research Excellence Fund,Medicine by Design(to CMM)。; Over the last two decades,the dogma that cell fate is immutable has been increasingly challenged,with important implications for regenerative medicine.The brea kth rough discovery that induced pluripotent stem cells c...; 关键词：programming PASSING proof

Immunomodulatory behavior of CircRNAs in tumor microenvironment: 《Oncology Research》2025年第5期1105-1119,共15页HAISU LIANG WEI YAN ZHI LIU YUNBO HE JIAO HU ZHIWEI SHU HUIHUANG LI BELAYDI OTHMANE WENBIAO REN CHAO QUAN DONGXU QIU MINFENG CHEN WEI XIONG BINGNAN ZHANG PEIHUA LIU; supported by the National Natural Science Foundation of China(82103298);Basic Research Project of Science and Technology Cooperation in Qiandongnan Prefecture(No.2023-16).; Circular RNAs(circRNAs)are a type of non coding RNA that possess unique single stranded circular structures formed through reverse splicing mechanisms.Due to the lack of a free end that is typically susceptible to deg...; 关键词：Circular RNA(circRNA) Immune response Metabolic reprogramming TUMOR Tumor microenvironment(TME)

Investigating Müller glia reprogramming in mice: a retrospective of the last decade, and a look to the future: 《Neural Regeneration Research》2025年第4期946-959,共14页Zhiyuan Yin Jiahui Kang Xuan Cheng Hui Gao Shujia Huo Haiwei Xu; supported by the National Natural Science Foundation of China,No.31930068;National Key Research and Development Program of China,Nos.2018YFA0107302 and 2021YFA1101203(all to HX).; Müller glia,as prominent glial cells within the retina,plays a significant role in maintaining retinal homeostasis in both healthy and diseased states.In lower vertebrates like zebrafish,these cells assume responsibi...; 关键词：cell fusion chemical small-molecules EPIGENETIC extracellular matrix immune metabolic MICE Müller glia neurodegenerative diseases REPROGRAMMING retina regeneration

Metabolic reprogramming: a new option for the treatment of spinal cord injury: 《Neural Regeneration Research》2025年第4期1042-1057,共16页Jiangjie Chen Jinyang Chen Chao Yu Kaishun Xia Biao Yang Ronghao Wang Yi Li Kesi Shi Yuang Zhang Haibin Xu Xuesong Zhang Jingkai Wang Qixin Chen Chengzhen Liang; supported by the National Natural Science Foundation of China,No.82202681(to JW);the Natural Science Foundation of Zhejiang Province,Nos.LZ22H090003(to QC),LR23H060001(to CL).; Spinal cord injuries impose a notably economic burden on society,mainly because of the severe after-effects they cause.Despite the ongoing development of various therapies for spinal cord injuries,their effectiveness ...; 关键词：AXONS GLYCOLYSIS metabolic reprogramming metabolism mitochondria neural regeneration NEUROPROTECTION oxidative phosphorylation spinal cord injury therapy

Effect of in vivo reprogramming of astrocytes combined with exercise training on neurorepair in rats with spinal cord injury: 《Animal Models and Experimental Medicine》2025年第4期595-605,共11页Zuliyaer Talifu Xin Xu Huayong Du Zehui Li Xiaoxin Wang Chunjia Zhang Yunzhu Pan Han Ke Wubo Liu Feng Gao Degang Yang Yingli Jing Yan Yu Liangjie Du Jianjun Li; Background:The inability of damaged neurons to regenerate and of axons to estab-lish new functional connections leads to permanent functional deficits after spinal cord injury(SCI).Although astrocyte reprogramming hol...; 关键词：ASTROCYTE exercise training functional recovery REPROGRAMMING spinal cord injury

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