云南高校图书馆联盟文献共享服务平台- LACTATE

LACTATE: 作品数：220被引量：487H指数：10; 导出分析报告; 相关领域：医药卫生更多>>; 相关作者：孙凤艳李学君刘建文许玲刘嘉湘更多>>; 相关机构：云南农业大学北京大学山东大学上海医科大学更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金国家重点基础研究发展计划重庆市自然科学基金广东省自然科学基金更多>>

Metabolic reprogramming of astrocytes:Emerging roles of lactate: 《Neural Regeneration Research》2026年第2期421-432,共12页Zeyu Liu Yijian Guo Ying Zhang Yulei Gao Bin Ning; supported by the National Natural Science Foundation of China,Nos.82071383,82371392(to BN);the Natural Science Foundation of Shandong Province of China(Key Project),No.ZR2020KH007(to BN);“Taishan Scholar Distinguished Expert Program”of Shandong Province,No.tstp20231257(to BN);Health Commission Science and Technology Plan Project of Jinan,No.2023-1-8(to YZ).; Lactate serves as a key energy metabolite in the central nervous system,facilitating essential brain functions,including energy supply,signaling,and epigenetic modulation.Moreover,it links epigenetic modifications wit...; 关键词：ASTROCYTE epigenetic modifications inflammation LACTATE lactylation METABOLIC PLASTICITY regeneration treatment

Lactate is a potentially harmful substitute for brain glucose fuel:consequences for metabolic restoration of neurotransmission: 《Neural Regeneration Research》2025年第5期1403-1404,共2页Oliver Kann Lennart Soder Babak Khodaie; The metabolite lactate (L-lactate) can be generated and released by diverse brain cells,including neurons,astrocytes,and oligodendrocytes (Kann,2023;Rae et al.,2024).Lactate production usually requires the degradation...; 关键词：consequences FIGURE RESTORATION

A portable,low-cost lactate measurement system: 《Journal of Measurement Science and Instrumentation》2025年第1期37-46,共10页WANG Qingqing PAN Yu YU Chuanxin WANG Yanyan ZHANG Kaikai LIU Sheng; supported by National Natural Science Foundation of China(No.62006092);Natural Science Research Project of Anhui Educational Committee(No.2023AH030081);2023 New Era Education Provincial Quality Engineering Project(Graduate Education)(No.2023cxcysj103);2024 New Era Education Provincial Quality Engineering Project(Graduate Education)。; Lactate,as a metabolite,plays a significant role in a number of fields,including medical diagnostics,exercise physiology and food science.Traditional methods for lactate measurement often involve expensive and cumbers...; 关键词：lactate measurement portable device embedded development lactate sensor electrochemical analysis

Dual activation of GCGR/GLP1R signaling ameliorates intestinal fibrosis via metabolic regulation of histone H3K9 lactylation in epithelial cells: 《Acta Pharmaceutica Sinica B》2025年第1期278-295,共18页Han Liu Yujie Hong Hui Chen Xianggui Wang Jiale Dong Xiaoqian Li Zihan Shi Qian Zhao Longyuan Zhou JiaXin Wang Qiuling Zeng Qinglin Tang Qi Liu Florian Rieder Baili Chen Minhu Chen Rui Wang Yao Zhang Ren Mao Xianxing Jiang; supported by the National Key R&D Program of China(2023YFC2507300);the National Natural Science Foundation of China(82273761,81970483,82170537 and 82222010);the Medical Innovation and Development Project of Lanzhou University(lzuyxcx-2022-156,China).; Intestinal fibrosis is a significant clinical challenge in inflammatory bowel diseases,but no effective anti-fibrotic therapy is currently available.Glucagon receptor(GCGR)and glucagon-like peptide 1 receptor(GLP1R)ar...; 关键词：Glucagon receptor Glucagon-likepeptide1 receptor LACTATE GLYCOLYSIS Post translational modification Epithelial-to-mesenchymal transition Intestinal fibrosis PEPTIDE

Microglia lactylation in relation to central nervous system diseases: 《Neural Regeneration Research》2025年第1期29-40,共12页Hui Yang Nan Mo Le Tong Jianhong Dong Ziwei Fan Mengxian Jia Juanqing Yue Ying Wang; The development of neurodegenerative diseases is closely related to the disruption of central nervous system homeostasis.Microglia,as innate immune cells,play important roles in the maintenance of central nervous syst...; 关键词：brain central nervous system GLYCOLYSIS immune response INFLAMMATION lactate metabolism LACTATE lactylation MICROGLIA neurodegenerative diseases

Current knowledge about pyruvate supplementation:A brief review被引量：1: 《Sports Medicine and Health Science》2024年第4期295-301,共7页Robert A.Olek Sylwester Kujach Zsolt Radak; Pyruvate is a three-carbon ketoacid that occurs naturally in cells.It is produced through enzymatic reactions in the glycolytic pathway and plays a crucial role in energy metabolism.Despite promising early results,lat...; 关键词：ACIDOSIS BICARBONATE LACTATE Nicotinamide adenine dinucleotide SIRTUINS

Molecularly imprinted fluorescence sensor chip for lactate measurement: 《Microsystems & Nanoengineering》2024年第6期189-201,共13页Muersha Wusiman Fariborz Taghipour; financial support received from the Natural Sciences and Engineering Research Council of Canada(NSERC).; Lactate measurements provide an opportunity to conveniently evaluate bodily functions and sports performance.A molecularly imprinted fluorescence biochip provides an innovative way to achieve lactate measurement and o...; 关键词：OVERCOME LIMITATIONS BORON

Lactate-mediated medium-chain fatty acid production from expired dairy and beverage waste: 《Environmental Science and Ecotechnology》2024年第5期278-286,共9页Bin Bian Wenxiang Zhang Najiaowa Yu Wei Yang Jiajie Xu Bruce E.Logan Pascal E.Saikaly; supported by a Competitive Research Grant(URF/1/4069-01-01);Research Translation Fund(REI/1/4576-01-01)from King Abdullah University of Science and Technology(KAUST),Saudi Arabia.; Fruits,vegetables,and dairy products are typically the primary sources of household food waste.Currently,anaerobic digestion is the most used bioprocess for the treatment of food waste with concomitant generation of b...; 关键词：Microbial chain elongation Medium chain carboxylic acids Food waste FERMENTATION

Traceable Lactate-Fueled Self-Acting Photodynamic Therapy against Triple-Negative Breast Cancer: 《Research》2024年第3期723-733,共11页Yifan Zhang Guangle Feng Ting He Min Yang Jing Lin Peng Huang; the National Key R&D Program of China(2018YFA0704000 and 2020YFA0908800);the National Natural Science Foundation of China(82372116,82071985,and 22104094);the Basic Research Program of Guangdong(2022A1515010620);the Basic Research Program of Shenzhen(JCYJ20200109105620482,JCYJ20220818095806014,and KQTD20190929172538530).; The depth of light penetration and tumor hypoxia restrict the efficacy of photodynamic therapy(PDT)in triple-negative breast cancer(TNBC),while the overproduction of lactate(LA)facilitates the development,aggressivene...; 关键词：BREAST THERAPY MANGANESE

Lactate activates CCL18 expression via H3K18 lactylation in macrophages to promote tumorigenesis of ovarian cancer被引量：1: 《Acta Biochimica et Biophysica Sinica》2024年第9期1373-1386,共14页Jinrui Sun Qinmei Feng Yue He Ming Wang Yumei Wu; This study investigates the role of lactate in the genesis and progression of ovarian cancer(OV)and explores the underlying mechanisms.Serum lactate levels show a positive correlation with tumor grade and poor prognos...; 关键词：ovarian cancer LACTATE MACROPHAGE CCL18 lactylation

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