Pyruvate is a three-carbon ketoacid that occurs naturally in cells.It is produced through enzymatic reactions in the glycolytic pathway and plays a crucial role in energy metabolism.Despite promising early results,lat...
LBMCC:“Recherche Cancer et Sang”foundation,the“Recherches Scientifiques Luxembourg”,the“Een Harz fir kriibskrank Kanner”,the Action LIONS“Vaincre le Cancer”and Télévie Luxembourg.SNU:National Research Foundation(NRF)(Grant Number 370C-20220063);MEST of Korea for Tumor Microenvironment Global Core Research Center(GCRC)(Grant Number 2011-0030001);Brain Korea(BK21)PLUS program and Creative-Pioneering Researchers Program at Seoul National University(Funding number:370C-20160062).Sruthi Reddy Gajulapalli and Ridhika Rajora were supported by grants for the“Graduate Scholarship for Excellent Foreign Students”program.
Chronicmyeloid leukemia(CML)is a lethal hematopoietic malignancy with a global incidence primarily attributed to the breakpoint cluster region-Abelson(BCR-ABL1)fusion oncogene in over 95%of cases.The introduction of t...