BREAST

作品数：1171被引量：1837H指数：17
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相关机构：首都医科大学复旦大学附属肿瘤医院中国医科大学附属第一医院中南大学更多>>
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Concurrent invasive ductal carcinoma and ductal carcinoma in situ arising inside and outside a breast hamartoma:A case report
《World Journal of Clinical Cases》2025年第18期53-59,共7页Lai Wei Zhe Tian Zhi-Yong Wang Wei-Jia Liu Hong-Bo Li Ying Zhang 
Supported by Jilin City Science and Technology Innovation Development Plan Project,China,No.20230406201;Jilin Province Traditional Chinese Medicine Technology Project,China,No.2024159.
BACKGROUND Breast hamartomas are rare benign breast tumors,with an incidence rate of 0.8%-4.8%.Further,the coexistence of hamartomas and carcinoma is also uncommon.Our case report presents a unique instance where inva...
关键词：BREAST HAMARTOMA Ductal carcinoma in situ Invasive ductal carcinoma Case report 
TMEM132E ablation suppresses tumor progression and restores tamoxifen sensitivity by inducing ERαexpression in triple-negative breast cancer
《Genes & Diseases》2025年第2期37-40,共4页Shang Gao Ping Sun Zekun Wang Yecheng Jin Wenjie Sun Xi Li Ruonan Duan Jiangxia Li Qiji Liu 
supported by grants from the National Key R&D Program of China (No.2022YFC2703701 to Qiji Liu);the National Natural Science Foundation of China (No.82271901,32070586);the Shandong Provincial Natural Science Foundation,China (No.ZR2020MH086);Taishan Scholar Program of Shandong Province (tsqn202211318);NHC Key Laboratory of Birth Defects Prevention,China (No.ZD202101).
Triple-negative breast cancer(TNBC)is defined by the lack of estrogen receptor(ER),progesterone receptor,and amplified human epidermal growth factor receptor expression.TNBC accounts for~15%of all breast cancer cases ...
关键词：expression. BREAST cancer 
FOXK1 promotes hormonally responsive breast carcinogenesis by suppressing apoptosis
《Animal Models and Experimental Medicine》2025年第4期638-648,共11页Minghui Zhao Tingyao Ma Zhaohan Zhang Yu Wang Xilin Wang Wenjuan Wang Xiaohong Chen Ran Gao Lin Shan 
Beijing High-Level Innovation and Entrepreneurship Talent Support Plan,Grant/Award Number:G04070024;National Natural Science Foundation of China,Grant/Award Number:82073122。
Background:Globally,breast cancer constitutes the predominant malignancy in women.Abnormal regulation of epigenetic factors plays a key role in the development of tumors.Anti-apoptosis is a characteristic of tumor cel...
关键词：APOPTOSIS estrogen receptor-positive breast cancer FOXK1 transcription repression 
Heterogeneity of anoikis in triple-negative breast cancer subtyping and therapeutic implications
《Genes & Diseases》2025年第1期114-117,共4页Kun Fang Suxiao Jiang Zhengjie Xu Meng Luo Changsheng Yan 
supported by a Ningxia Reproductive Disease Clinical Medical Research Center Project(2023-LCYX003);Ningxia Hui Autonomous Region Natural Science Foundation Project(2022AAC03748);Ningxia Hui Autonomous Region Natural Science Foundation Project(2021AAC03523);Yinchuan Science and Technology Innovation Project(2023SF25);Basic research project of Yinchuan Maternal and Child Health Hospital(2022NYFYCX05);Basic research project of Yinchuan Maternal and Child Health Hospital(2023NYFYCX01).
Triple-negative breast cancer(TNBC)is an inherently heterogeneous malignancy at the biological and clinical levels,occupying around 15%of diagnosed breast cancer cases and being the most lethal breast cancer subtype t...
关键词：BREAST cancer clinical 
Neoadjuvant HER2 inhibition induces ESR1 DNA methylation alterations resulting in clinically relevant ER expression changes in breast cancers
《Cancer Communications》2025年第2期198-202,共5页Gavin P.Dowling Gordon R.Daly Aisling Hegarty Michael Flanagan Mihaela Ola Ramón Fallon Sinéad Cocchiglia Vikrant Singh Katherine M.Sheehan Fiona Bane Jason McGrath Louise Watson Sandra Hembrecht Bryan Hennessy Patrick G.Morris Arnold D.K.Hill Damir Varešlija Leonie S.Young 
support from Science Foundation Ireland Frontiers for the Future Award(19/FFP/6443);Science Foundation Ireland Strategic Partnership Program,Precision Oncology Ireland(18/SPP/3522)(L.S.Y.);Breast Cancer Now Fellowship Award with the generous support of Walk the Walk(2019AugSF1310)(D.V.);Science Foundation Ireland(20/FFP-P/8597)(D.V.);Breast Cancer Ireland program Grant(18239A01)(L.S.Y.).
The expression of estrogen receptor(ER)and human epidermal growth factor receptor-2(HER2)in breast cancer can change in response to treatment and pivotally influence tumor behavior and clinical management[1].Receptor ...
关键词：alterations HER2 BREAST 
Survival with Trastuzumab Emtansine in Residual HER2-Positive Breast Cancer
《四川生理科学杂志》2025年第1期145-145,共1页Charles E Geyer Jr 
Background:Patients with human epidermal growth factor receptor 2(HER2)-positive early breast cancer with residual invasive disease after neoadjuvant systemic therapy have a high risk of recurrence and death.The prima...
关键词：SURVIVAL CANCER BREAST 
Carcinosarcoma of the breast:Facing the challenge of a rare nosologic entity
《World Journal of Clinical Cases》2025年第2期14-20,共7页Aikaterini Mastoraki Maria Tsamopoulou Foivos-Konstantinos Stamatis Alexios Strimpakos Ero Mouchtouri Christiana Panagi Evgenia Mela Sotiria Mastoraki Aristotelis Kechagias Dimitrios Schizas 
Carcinosarcoma(CS),also known as metaplastic breast carcinoma with mesenchymal differentiation,is one of the five distinct subtypes of metaplastic breast cancer.It is considered as a mixed,biphasic neoplasm consisting...
关键词：CARCINOSARCOMA BREAST Diagnostic approach Therapeutic management Prognostic parameters 
Macrophages promote pre-metastatic niche formation of breast cancer through aryl hydrocarbon receptor activity
《Signal Transduction and Targeted Therapy》2025年第1期369-383,共15页Xu Jiang Jiaqi Wang Liangyu Lin Liming Du Yayun Ding Fanjun Zheng Hongzhen Xie Yu Wang Mingyuan Hu Benming Liu Muhan Xu Jingjie Zhai Xuefeng Wang Jiayin Ye Wei Cao Chao Feng Jingyi Feng Zongliu Hou Mingyao Meng Ju Qiu Qing Li Yufang Shi Ying Wang 
support for the research of this work from the National Key R&D Program of China(2022YFA0807300);National Natural Science Foundation of China(82425032,32070872,31771641);Y.S.discloses support for the research of this work from National Natural Science Foundation of China(82430086,81930085);L.L.discloses support for the research of this work from the National Natural Science Foundation of China(82470658);a Fellowship of China Postdoctoral Science Foundation(2020M671261);Q.L.discloses support for the research of this work from the National Natural Science Foundation of China(82301571).
Macrophages that acquire an immunosuppressive phenotype play a crucial role in establishing the pre-metastatic niche (PMN),which is essential for facilitating breast cancer metastasis to distant organs. Our study show...
关键词：BREAST METASTATIC METASTASIS 
Neural network architecture search enabled wide-deep learning(NAS-WD)for spatially heterogenous property awared chicken woody breast classification and hardness regression
《Artificial Intelligence in Agriculture》2024年第4期73-85,共13页Chaitanya Pallerla Yihong Feng Casey M.Owens Ramesh Bahadur Bist Siavash Mahmoudi Pouya Sohrabipour Amirreza Davar Dongyi Wang 
support by the University of Arkansas Experimental Station and the University of Arkansas College of Engineering,USDA National Institute of Food and Agriculture (No:2023-70442-39232,2024-67022-42882).
Due to intensive genetic selection for rapid growth rates and high broiler yields in recent years,the global poultry industry has faced a challenging problem in the form of woody breast(WB)conditions.This condition ha...
关键词：Network architecture search Wide-deep learning BROILER Woody breast Hardness distribution map 
Transformation of Malignant Phyllodes Tumors into Benign Tumors in Tumor Recurrence: A Case Report
《Case Reports in Clinical Medicine》2024年第12期558-565,共8页Mohammad Mahdi Talimkhani Ali Yamini Leili Ebrahimi Farsangi Aida Alizamir Shaghayegh Shamekhi Mohammad Mahdi Gholami Mohamad Reza Javadi 
Objective: Phyllodes tumors (PTs) are rare, distinctive fibroepithelial neoplasms. They are associated with a low incidence and comprise 0.3% - 0.9% of all breast tumors. Recurrence occurs in about 20% of cases, and m...
关键词：Phyllodes Tumor of the Breast Breast Neoplasms Neoplasm Recurrence LOCAL 
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