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METASTASIS: 作品数：1858被引量：6797H指数：32; 导出分析报告; 相关领域：医药卫生更多>>; 相关作者：吴东明唐休发华成舸房居高徐伟更多>>; 相关机构：中山大学江苏省人民医院第二军医大学四川大学更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金国家重点基础研究发展计划中国博士后科学基金广东省自然科学基金更多>>

Brain and scalp metastasis of cervical cancer in a patient with human immunodeficiency virus infection:A case report: 《World Journal of Clinical Cases》2025年第19期65-71,共7页Hui-Qiong Huang Feng-Ming Gong Chun-Tang Sun Yu Xuan Lin Li; Supported by the Sichuan Science and Technology Program,No.2022NSFSC0797.; BACKGROUND Cervical cancer is the most commonly diagnosed cancer worldwide and the most common cancer in females living with human immunodeficiency virus(HIV).Cervical cancer is classified as an acquired immune defici...; 关键词：Brain metastasis Cervical cancer Antiretroviral therapy Multi-modal treatment Case report

Cytoplasmic and nuclear programmed death ligand 1 expression in peritumoral stromal cells in breast cancer:Prognostic and predictive value: 《World Journal of Experimental Medicine》2025年第2期150-170,共21页Evgeniya Yu Zubareva Marina A Senchukova Natalia V Saidler; Supported by Russian Science Foundation,No.23-25-00183.; BACKGROUND Breast cancer(BC)continues to occupy a leading position in terms of morbidity and mortality from malignant neoplasms among the female population.One of the promising markers associated with BC progression i...; 关键词：Breast cancer Programmed death-ligand 1 Regional metastasis Tumor stroma

Transcription factor ELF4 in physiology and diseases:Molecular roles and clinical implications: 《Genes & Diseases》2025年第3期329-346,共18页Dian Hu Zerui Zhang Yijun Wang Siwen Li Jiaqian Zhang Zhangfan Wu Mengyu Sun Junqing Jiang Danfei Liu Xiaoyu Ji Shuai Wang Yufei Wang Xiangyuan Luo Wenjie Huang Limin Xia; funded by the National Natural Science Foundation of China(No.U23A20451,82273310,82372917,82173313);the Natural Science Foundation of Hubei Province,China(No.2022CFA016);the Basic Research Support Program of Huazhong University of Science and Technology(China)(No.2023BR038).; Transcription factor E74 like ETS transcription factor 4(ELF4),a member of the ETS family,is highly expressed in normal human hematopoietic tissue,ovary,placenta,colon,and certain pathological cell lines.During normal...; 关键词：BIOMARKER Cancer ELF4/MEF Immune system METASTASIS

Isoleucyl-tRNA synthetase 2 promotespancreatic ductal adenocarcinomaproliferation and metastasis by stabilizingb-catenin: 《Genes & Diseases》2025年第3期478-491,共14页Yixun Jin Xinyang Huang Zhuoxin Wang Berik Kouken Qi Wang Lifu Wang; supported by the National Natural Science Foundation of China(No.81870385,81702740).; Isoleucyl-tRNA synthetase 2(IARS2),originally regarded as an enzyme ligatingisoleucine to the corresponding tRNA,has been identified as an oncogene recently.However,its function in pancreatic ductal adenocarcinoma(PDA...; 关键词：Aminoacyl-tRNA synthetases Isoleucyl-tRNA synthetase 2 Pancreatic ductal adenocarcinoma WNT signaling pathway b-Catenin

Dynamics of epithelial-mesenchymal plasticity driving cancer drug resistance: 《Cancer Pathogenesis and Therapy》2025年第2期120-128,共9页Rashmi Bangarh Reena V.Saini Adesh K.Saini Tejveer Singh Hemant Joshi Seema Ramniwas Moyad Shahwan Hardeep Singh Tuli; supported by the DST-INSPIRE(Department of Science&Technology-Innovation in Science Pursuit for Inspired Research)Fellowship(No.IF210078);the Department of Science and Technology(Technology Development Program),Government of India(No.TDP/BDTD/54/2021/General);the Indian Council of Medical Research-Department of Health Research(ICMR-DHR)Young Scientist Fellowship(F.No:R.12014/29/2022/HR).; Epithelial-mesenchymal transition(EMT)promotes several cancers by increasing tumor cell motility,disrupting epithelial cell phenotypes,apical-basal polarity,and intracellular connections,and enhancing tumor resistance...; 关键词：Epithelial-mesenchymal transition Tumor microenvironment METASTASIS Cancer drug resistance

Promising roles of vitamin D receptor and APRO family proteins for the development of cancer stem cells targeted malignant tumor therapy: 《Oncology Research》2025年第5期1007-1017,共11页MOEKA NAKASHIMA NAOKO SUGA AKARI FUKUMOTO SAYURI YOSHIKAWA SATORU MATSUDA; Malignant tumors are heterogeneous diseases characterized by uncontrolled cell proliferation,invasion,metastasis,and/or recurrence of their malignancies.In particular,cancer stem cells(CSCs)within these tumors might b...; 关键词：Vitamin D Cancer stem cell INVASION METASTASIS CHEMORESISTANCE Ferroptosis Tumor microenvironment Noncoding RNAs Cancer therapy

OTUB2 promotes proliferation and metastasis of triple-negative breast cancer by deubiquitinating TRAF6: 《Oncology Research》2025年第5期1135-1147,共13页YU QIU RUIHAN LIU SHANSHAN HUANG QIAOTING CAI YI XIE ZHITING HE WEIGE TAN XINHUA XIE; supported by the National Natural Science Foundation of China(No.82373380,Xinhua Xie).; Objectives:Deubiquitinase OTUB2 plays a critical role in the progression of various tumors.However,its specific role in triple-negative breast cancer(TNBC)remains unclear.This study aims to elucidate the biological fu...; 关键词：OTUB2 Tumor necrosis factor receptor-associated factor 6(TRAF6) Triple-Negative Breast Cancer(TNBC) DEUBIQUITINATION

Radiomics and machine learning for predicting metachronous liver metastasis in rectal cancer: 《World Journal of Gastrointestinal Oncology》2025年第4期541-544,共4页Arunkumar Krishnan; A recent study by Long et al used a predictive model to explore the efficacy of radiomics based on multiparametric magnetic resonance imaging in predicting metachronous liver metastasis(MLM)in newly diagnosed rectal c...; 关键词：Rectal cancer Liver metastases NEOPLASM METASTASIS Machine learning Magnetic resonance imaging Radiomics

SIK2 promotes malignant features of human osteosarcoma via up-regulating MMP2 andβ-catenin expression: 《Genes & Diseases》2025年第2期83-85,共3页Yutong Wang Yulan Yao Sen Kou Shanshan Wang Juntao Song Siqi Yang Hongwei Wang Yunliang Wang; Osteosarcoma is a primary malignant bone tumor that commonly occurs in children and adolescents.It is highly malignant and prone to metastasis,with a very poor prognosis.There is currently no effective treatment for t...; 关键词：MALIGNANT OSTEOSARCOMA METASTASIS

Inhibition of ITGA2 suppresses cervical tumorigenesis and metastasis by targeting the AKT/mTOR signaling pathway: 《Genes & Diseases》2025年第2期86-89,共4页Haixia Luo Jingjing Chang Yiting Ren Xiu Zhang Yuanxing Li Miao Huo Hongyuan Wang Xin Yang Jianbing Liu Qingmei Zhang Yueyang Zhao Wei Wang; supported by grants from the Applied Basic Research Program of Shanxi,China (No.20210302123277);the Key Research and Development Program of Shanxi,China (No.201903D321152);the National Natural Science Foundation of China (No.82373107).; Cervical cancer(CCa)is a substantial global health concern,and its lymph node metastasis(LNM)significantly diminishes patients'survival rates.1 Hence,a thorough investigation into the molecular mechanisms driving this...; 关键词：METASTASIS ITG cancer

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