Supported by Beijing Bethune Charitable Foundation and Provincial Natural Science Foundation of Liaoning,No.2022-MS-190.
BACKGROUND Circulating tumor DNA(ctDNA)-based liquid biopsy has been found to be effective for the detection of minimal residual disease and the evaluation of prognostic risk in various solid tumors,with good sensitiv...
supported by the National Natural Science Foundation of China(Nos.U23A20573,U23A20140,22072154,and 22377127);Hebei Natural Science Foundation(B2024208046 and H2022423314);Huang jin tai plan project of Hebei provincial department of education(HJZD202512);S&T Program of Hebei,the Youth innovation Promotion Association of Chinese Academy of Sciences(No.2021048);the Beijing Nova Program(No.20230484352).
Sonodynamic therapy(SDT)as an emerging modality for malignant tumors mainly involves in sonosensitizers and low-intensity ultrasound(US),which can safely penetrate the tissue without significant attenuation.SDT not on...
Supported by Comisión Sectorial de Investigación Científica(CSIC-Research Group 88180);The Agencia Nacional de Investigación e Innovación/Sistema Nacional de Investigadores(ANII/SNI);The Programa de Desarrollo de las Ciencias Básicas(PEDECIBA),Uruguay.
BACKGROUND Hypoxia in oral cancer promotes tumoral invasion by inducing epithelial-mesenchymal transition,leading to aggressive tumor progression.AIM To characterize the expression of hypoxia-inducible factor 1-alpha(...
Endometrial carcinoma(EC)is a prevalent gynecological cancer,and its interaction with the immune system is pivotal in cancer progression.This comprehensive review explores the molecular mechanisms involved in the regu...
supported by the National Natural Science Foundation of China(82103298);Basic Research Project of Science and Technology Cooperation in Qiandongnan Prefecture(No.2023-16).
Circular RNAs(circRNAs)are a type of non coding RNA that possess unique single stranded circular structures formed through reverse splicing mechanisms.Due to the lack of a free end that is typically susceptible to deg...
Supported by the National Natural Science Foundation of China(No.82220108017,No.82141128,No.82101180);Beijing Natural Science Foundation(No.Z220012);The Capital Health Research and Development of Special(No.2020-1-2052);Science&Technology Project of Beijing Municipal Science&Technology Commission(No.Z201100005520045);Sanming Project of Medicine in Shenzhen(No.SZSM202311018);Beijing Science&Technology Development of TCM(No.BJZYYB-2023-17).
AIM:To explore the relationship between matrix metalloproteinases(MMPs)expression levels in the tumor and the prognosis of uveal melanoma(UM)and to construct prognostic prediction models.METHODS:Transcriptome sequenci...
supported by the Foundation for Distinguished Young Scholars of medical science and technology innovation in Henan Province(No.YXKC2022033);Fund for Scientific Research and Innovation Team of The First Affiliated Hospital of Zhengzhou University(No.QNCXTD2023018);Scientific Research Projects of colleges and universities in Henan Province(No.24A320055).
Reasonable design and construction of artificial enzymes with excellent catalytic activity,good stability and superior biocompatibility is essential for tumor therapy.Single-atom site catalysts(SAs)with well-defined a...
supported by the Zhejiang Province Traditional Chinese Medicine Science and Technology Project(GZY-ZJ-KJ-24063);the Natural Science Foundation of Zhejiang Province(Q24H290031);the Key Laboratory for Molecular Medicine and Chinese Medicine Preparations(No.GZY-ZJ-SY-2303).
Immunotherapies have demonstrated notable clinical benefits in the treatment of cervical cancer(CC).However,the development of therapeutic resistance and diverse adverse effects in immunotherapy stem from complex inte...
BACKGROUND The prognosis of patients with poorly differentiated gastric neuroendocrine neoplasms(PDGNENs)is dismal and related research is limited.AIM To investigate the prognostic factors,and validate a novel prognos...
supported by the support for High-quality Development of Scientific Research Funding Project of China Medical University (No.2023JH2/20200137).
Lung adenocarcinoma(LUAD)is the primary subtype of lung cancer,but its prognosis remains challenging.The tumor microenvironment plays a central role in the initiation and development of tumors,particularly regarding t...