TUMOR

作品数:2163被引量:5599H指数:26
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相关领域:医药卫生更多>>
相关作者:孙汭田志刚郑晓东华成舸魏海明更多>>
相关机构:北京大学华中科技大学上海交通大学四川大学更多>>
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相关基金:国家自然科学基金国家重点基础研究发展计划中国博士后科学基金广东省自然科学基金更多>>
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Application of circulating tumor DNA liquid biopsy in nasopharyngeal carcinoma:A case report and review of literature
《World Journal of Clinical Cases》2025年第21期93-103,共11页Xin-Yao Zhou Yuan-Jun Jiang Xiao-Ming Guo Dong-Hui Han Yao Liu Qiao Qiao 
Supported by Beijing Bethune Charitable Foundation and Provincial Natural Science Foundation of Liaoning,No.2022-MS-190.
BACKGROUND Circulating tumor DNA(ctDNA)-based liquid biopsy has been found to be effective for the detection of minimal residual disease and the evaluation of prognostic risk in various solid tumors,with good sensitiv...
关键词:Nasopharyngeal cancer Radiation therapy Circulating tumor DNA Epstein–Barr virus Minor residual disease Guide treatment Predicting prognosis Case report 
Nanomaterials Enhanced Sonodynamic Therapy for Multiple Tumor Treatment
《Nano-Micro Letters》2025年第7期126-159,共34页Mengyao Yang Xin Wang Mengke Peng Fei Wang Senlin Hou Ruirui Xing Aibing Chen 
supported by the National Natural Science Foundation of China(Nos.U23A20573,U23A20140,22072154,and 22377127);Hebei Natural Science Foundation(B2024208046 and H2022423314);Huang jin tai plan project of Hebei provincial department of education(HJZD202512);S&T Program of Hebei,the Youth innovation Promotion Association of Chinese Academy of Sciences(No.2021048);the Beijing Nova Program(No.20230484352).
Sonodynamic therapy(SDT)as an emerging modality for malignant tumors mainly involves in sonosensitizers and low-intensity ultrasound(US),which can safely penetrate the tissue without significant attenuation.SDT not on...
关键词:Sonodynamic therapy Nanosonosensitizers Tumor accumulation Surmounting the hypoxia Orthotopic tumor 
Hypoxia-inducible factor-1αat the invasive tumor front in oral squamous cell carcinoma
《World Journal of Experimental Medicine》2025年第2期83-92,共10页Felipe Martins Silveira Lauren Frenzel Schuch Vanesa Pereira-Prado Nelly Molina-Frechero Sandra Lopez-Verdin Marcelo Gómez Palacio-Gastélum Miguel Arocena Sven Niklander Estefania Sicco Ronell Bologna-Molina 
Supported by Comisión Sectorial de Investigación Científica(CSIC-Research Group 88180);The Agencia Nacional de Investigación e Innovación/Sistema Nacional de Investigadores(ANII/SNI);The Programa de Desarrollo de las Ciencias Básicas(PEDECIBA),Uruguay.
BACKGROUND Hypoxia in oral cancer promotes tumoral invasion by inducing epithelial-mesenchymal transition,leading to aggressive tumor progression.AIM To characterize the expression of hypoxia-inducible factor 1-alpha(...
关键词:Hypoxia-inducible factor-1α Oral squamous cell carcinoma IMMUNOHISTOCHEMISTRY VIMENTIN E-CADHERIN 
Molecular mechanism of tumor-infiltrating immune cells regulating endometrial carcinoma
《Genes & Diseases》2025年第3期265-277,共13页Silu Ding Yingying Hao Yue Qi Heng Wei Jin Zhang Hui Li 
Endometrial carcinoma(EC)is a prevalent gynecological cancer,and its interaction with the immune system is pivotal in cancer progression.This comprehensive review explores the molecular mechanisms involved in the regu...
关键词:Clinical implication Endometrial carcinoma Immune checkpoint pathways Immune evasion strategies Tumor-infiltrating immune cells 
Immunomodulatory behavior of CircRNAs in tumor microenvironment
《Oncology Research》2025年第5期1105-1119,共15页HAISU LIANG WEI YAN ZHI LIU YUNBO HE JIAO HU ZHIWEI SHU HUIHUANG LI BELAYDI OTHMANE WENBIAO REN CHAO QUAN DONGXU QIU MINFENG CHEN WEI XIONG BINGNAN ZHANG PEIHUA LIU 
supported by the National Natural Science Foundation of China(82103298);Basic Research Project of Science and Technology Cooperation in Qiandongnan Prefecture(No.2023-16).
Circular RNAs(circRNAs)are a type of non coding RNA that possess unique single stranded circular structures formed through reverse splicing mechanisms.Due to the lack of a free end that is typically susceptible to deg...
关键词:Circular RNA(circRNA) Immune response Metabolic reprogramming TUMOR Tumor microenvironment(TME) 
Prognostic prediction model for Chinese uveal melanoma patients based on matrix metalloproteinase-2 and-28 expression levels in the tumor
《International Journal of Ophthalmology(English edition)》2025年第5期765-778,共14页Yu-Ning Chen Jing-Ying Xiu Han-Qing Zhao Jing-Ting Luo Qiong Yang Yang Li Wen-Bin Wei 
Supported by the National Natural Science Foundation of China(No.82220108017,No.82141128,No.82101180);Beijing Natural Science Foundation(No.Z220012);The Capital Health Research and Development of Special(No.2020-1-2052);Science&Technology Project of Beijing Municipal Science&Technology Commission(No.Z201100005520045);Sanming Project of Medicine in Shenzhen(No.SZSM202311018);Beijing Science&Technology Development of TCM(No.BJZYYB-2023-17).
AIM:To explore the relationship between matrix metalloproteinases(MMPs)expression levels in the tumor and the prognosis of uveal melanoma(UM)and to construct prognostic prediction models.METHODS:Transcriptome sequenci...
关键词:uveal melanoma matrix metalloproteinases prediction model PROGNOSIS tumor microenvironment 
Biocompatible copper single-atom site nanozyme for parallel tumor therapy
《Nano Research》2025年第4期337-345,共9页Haining Zhou Hui Peng Yugui Lian Ting Sun Chang Su Zhiyuan Wang 
supported by the Foundation for Distinguished Young Scholars of medical science and technology innovation in Henan Province(No.YXKC2022033);Fund for Scientific Research and Innovation Team of The First Affiliated Hospital of Zhengzhou University(No.QNCXTD2023018);Scientific Research Projects of colleges and universities in Henan Province(No.24A320055).
Reasonable design and construction of artificial enzymes with excellent catalytic activity,good stability and superior biocompatibility is essential for tumor therapy.Single-atom site catalysts(SAs)with well-defined a...
关键词:single copper atom catalysts nanozyme reactive oxygen species photothermal therapy TUMOR 
Omics sciences for cervical cancer precision medicine from the perspective of the tumor immune microenvironment
《Oncology Research》2025年第4期821-836,共16页GUANTING PANG YAOHAN LI QIWEN SHI JINGKUI TIAN HANMEI LOU YUE FENG 
supported by the Zhejiang Province Traditional Chinese Medicine Science and Technology Project(GZY-ZJ-KJ-24063);the Natural Science Foundation of Zhejiang Province(Q24H290031);the Key Laboratory for Molecular Medicine and Chinese Medicine Preparations(No.GZY-ZJ-SY-2303).
Immunotherapies have demonstrated notable clinical benefits in the treatment of cervical cancer(CC).However,the development of therapeutic resistance and diverse adverse effects in immunotherapy stem from complex inte...
关键词:OMICS Tumor immune microenvironment(TIME) Precision medicine Cervical cancer(CC) 
Construction and validation of a novel prognostic nomogram for patients with poorly differentiated gastric neuroendocrine neoplasms
《World Journal of Clinical Oncology》2025年第4期142-153,共12页Ben-Long Zhang Fei Peng Li Li Yun-He Gao Zi-Jian Wang Yi-Xun Lu Lin Chen Ke-Cheng Zhang 
BACKGROUND The prognosis of patients with poorly differentiated gastric neuroendocrine neoplasms(PDGNENs)is dismal and related research is limited.AIM To investigate the prognostic factors,and validate a novel prognos...
关键词:Gastric neuroendocrine neoplasms Poorly differentiated tumor NOMOGRAM PROGNOSIS Overall survival 
The important role and core marker gene of tumor-infiltrating plasma cells in the microenvironment of lung adenocarcinoma
《Genes & Diseases》2025年第2期11-14,共4页Jianhong Zhang Chengyang Song Xiuqin Feng QianYu Xueying Yang 
supported by the support for High-quality Development of Scientific Research Funding Project of China Medical University (No.2023JH2/20200137).
Lung adenocarcinoma(LUAD)is the primary subtype of lung cancer,but its prognosis remains challenging.The tumor microenvironment plays a central role in the initiation and development of tumors,particularly regarding t...
关键词:ADENOCARCINOMA LUNG PROGNOSIS 
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