funded by grants from the Spanish Ministry of Science,Innovation and Universities(Ref.PID2019-110356RB-I00/AEI/10.13039/501100011033)to JFI and ES;the Department of Economic and Business Development from Government of Navarra(Ref.0011-1411-2023-000028 to ES);supported by a predoctoral fellowship from the Public University of Navarra(UPNA);supported by a postdoctoral fellowship from Miguel Servet Foundation-Navarrabiomed;supported by“Programa MRR Investigo 2023”in the framework of the European Union recovery and resilience facility。
Data-driven drug repositioning using olfactory omics profiles-challenges and perspectives in neurodegeneration:Neurodegenerative diseases are characterized by progressive degeneration and loss of neuronal function in ...
The brain,with its trillions of neural connections,different cellular types,and molecular complexities,presents a formidable challenge for researchers aiming to comprehend the multifaceted nature of neural health.As t...
supported by the Korea Health Technology R&D Project through the Korea Health Industry Development Institute (KHIDI);the Ministry of Health&Welfare,Republic of Korea (HR22C1734);the National Research Foundation (NRF) of Korea (2020R1A6A1A03043539,2020M3A9D8037604,2022R1C1C1004756)(to SBL);the NRF of Korea (2022R1C1C1005741 and RS-2023-00217595);the new faculty research fund of Ajou University School of Medicine (to EJL)。
Elucidating the complex dynamic cellular organization in the hypothalamus is critical for understanding its role in coordinating fundamental body functions. Over the past decade, single-cell and spatial omics technolo...
supported by the Multi-Center Clinical Research Project of the National Clinical Research Center for Geriatric Diseases(No.NCRCG-PLAGH-20230010);the Key Military Health Project(No.23BJZ25).
Chronic myelomonocytic leukemia(CMML),a rare and malignant hematologic disorder,is classified as a myelodysplastic/myeloproliferative neoplasm(MDS/MPN).1 It poses a significant risk of progression to acute myeloid leu...
supported by the Zhejiang Province Traditional Chinese Medicine Science and Technology Project(GZY-ZJ-KJ-24063);the Natural Science Foundation of Zhejiang Province(Q24H290031);the Key Laboratory for Molecular Medicine and Chinese Medicine Preparations(No.GZY-ZJ-SY-2303).
Immunotherapies have demonstrated notable clinical benefits in the treatment of cervical cancer(CC).However,the development of therapeutic resistance and diverse adverse effects in immunotherapy stem from complex inte...
In this editorial,we comment on the article by Micucci et al published in the recent issue.We focus on the heterogenous nature of gastric cancer(GC)and the potential benefits of integrating traditional Chinese medicin...
Chronic diseases such as heart disease,cancer,and diabetes are leading drivers of mortality worldwide,underscoring the need for improved efforts around early detection and prediction.The pathophysiology and management...
supported by Natural Science Foundation of Shandong Province(ZR2023JQ012);the National Natural Science Foundation of China(32101741);National Key Research and Development Program of China(2022YFD1201802);the Taishan Scholar Program of Shandong Provincial Government to F.X.,and National Natural Science Foundation of China(32201694 and U22A20460)to X.H.
All plant organs are derived from stem cell-containing meristems.In maize,the shoot apical meristem(SAM)is responsible for generating all above-ground structures,including the male and female inflorescence meristems(I...
This article discusses the manuscript recently published in the World Journal of Gastroenterology,which explores the application of deep learning models in decision-making processes via wireless capsule endoscopy.Inte...
financially supported by the National Key Research and Development Program(2022YFA1302902 to H.Z.);the Shanghai Municipal Science and Technology Major Project;supported by the Strategic Priority Research Program of the Chinese Academy of Sciences(XDB0830000);the National Natural Science Foundation of China(22425703 to H.Z.)。
Advancements in molecular characterization technologies have accelerated targeted cancer therapy research at unprecedented resolution and dimensionality.Integrating comprehensive multi-omic molecular profiling of a tu...