OMICS

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Data-driven drug repositioning using olfactory omics profiles:challenges and perspectives in neurodegeneration
《Neural Regeneration Research》2025年第7期1997-1998,共2页Paz Cartas-Cejudo Adriana Cortés Mercedes Lachén-Montes Elena Anaya-Cubero Joaquín Fernández-Irigoyen Enrique Santamaría 
funded by grants from the Spanish Ministry of Science,Innovation and Universities(Ref.PID2019-110356RB-I00/AEI/10.13039/501100011033)to JFI and ES;the Department of Economic and Business Development from Government of Navarra(Ref.0011-1411-2023-000028 to ES);supported by a predoctoral fellowship from the Public University of Navarra(UPNA);supported by a postdoctoral fellowship from Miguel Servet Foundation-Navarrabiomed;supported by“Programa MRR Investigo 2023”in the framework of the European Union recovery and resilience facility。
Data-driven drug repositioning using olfactory omics profiles-challenges and perspectives in neurodegeneration:Neurodegenerative diseases are characterized by progressive degeneration and loss of neuronal function in ...
关键词：DISEASES drug AMYLOID 
Single-cell pan-omics, environmental neurology, and artificial intelligence:the time for holistic brain health research
《Neural Regeneration Research》2025年第6期1703-1704,共2页Paolo Abondio Francesco Bruno 
The brain,with its trillions of neural connections,different cellular types,and molecular complexities,presents a formidable challenge for researchers aiming to comprehend the multifaceted nature of neural health.As t...
关键词：function artificial LANDSCAPE 
Single-cell and spatial omics:exploring hypothalamic heterogeneity
《Neural Regeneration Research》2025年第6期1525-1540,共16页Muhammad Junaid Eun Jeong Lee Su Bin Lim 
supported by the Korea Health Technology R&D Project through the Korea Health Industry Development Institute (KHIDI);the Ministry of Health&Welfare,Republic of Korea (HR22C1734);the National Research Foundation (NRF) of Korea (2020R1A6A1A03043539,2020M3A9D8037604,2022R1C1C1004756)(to SBL);the NRF of Korea (2022R1C1C1005741 and RS-2023-00217595);the new faculty research fund of Ajou University School of Medicine (to EJL)。
Elucidating the complex dynamic cellular organization in the hypothalamus is critical for understanding its role in coordinating fundamental body functions. Over the past decade, single-cell and spatial omics technolo...
关键词：cellular diversity HYPOTHALAMUS multi-omics single-cell transcriptomics spatial transcriptomics 
Traditional Chinese medicine and modern technology:Network pharmacology and omics sequencing in gastric cancer
《World Journal of Gastrointestinal Oncology》2025年第3期38-43,共6页Jessica Shapiro Gemmell Brandon Lucke-Wold 
In this editorial,we comment on the article by Micucci et al published in the recent issue.We focus on the heterogenous nature of gastric cancer(GC)and the potential benefits of integrating traditional Chinese medicin...
关键词：Gastric cancer Traditional Chinese medicine OMICS Network pharmacology NUTRACEUTICALS Precision medicine 
Artificial intelligence in gastroenterology:Ethical and diagnostic challenges in clinical practice
《World Journal of Gastroenterology》2025年第10期144-150,共7页Davide Ramoni Alessandro Scuricini Federico Carbone Luca Liberale Fabrizio Montecucco 
This article discusses the manuscript recently published in the World Journal of Gastroenterology,which explores the application of deep learning models in decision-making processes via wireless capsule endoscopy.Inte...
关键词：Artificial intelligence ENDOSCOPY Ethical implication Gastrointestinal disease Machine learning OMICS Precision medicine Wireless capsule endoscopy 
Advancements in proteogenomics for preclinical targeted cancer therapy research
《Biophysics Reports》2025年第1期56-76,共21页Yuying Suo Yuanli Song Yuqiu Wang Qian Liu Henry Rodriguez Hu Zhou 
financially supported by the National Key Research and Development Program(2022YFA1302902 to H.Z.);the Shanghai Municipal Science and Technology Major Project;supported by the Strategic Priority Research Program of the Chinese Academy of Sciences(XDB0830000);the National Natural Science Foundation of China(22425703 to H.Z.)。
Advancements in molecular characterization technologies have accelerated targeted cancer therapy research at unprecedented resolution and dimensionality.Integrating comprehensive multi-omic molecular profiling of a tu...
关键词：PROTEOGENOMICS Targeted cancer therapy Integrated omics analysis 
Soybean2035:A decadal vision for soybean functional genomics and breeding
《Molecular Plant》2025年第2期245-271,共27页Zhixi Tian Alexandre Lima Nepomuceno Qingxin Song Robert M.Stupar Bin Liu Fanjiang Kong Jianxin Ma Suk-Ha Lee Scott A.Jackson 
supported by the National Natural Science Foundation of China(grant nos.32388201 and 32372126);Fundamental Research Funds for the Central Universities(YDZX2024041).
Soybean,the fourth most important crop in the world,uniquely serves as a source of both plant oil and plant protein for the world’s food and animal feed.Although soybean production has increased approximately 13-fold...
关键词：SOYBEAN OMICS functional genomics molecular breeding artificial intelligence 
Wheat2035:Integrating pan-omics and advanced biotechnology for future wheat design被引量：1
《Molecular Plant》2025年第2期272-297,共26页Yingyin Yao Weilong Guo Jinying Gou Zhaorong Hu Jie Liu Jun Ma Yuan Zong Mingming Xin Wei Chen Qiang Li Zihao Wang Ruijie Zhang Cristobal Uauy Faheem Shehzad Baloch Zhongfu Ni Qixin Sun 
supported by the Key Program of the National Natural Science Foundation of China(32130078);the Major Program of the National Natural Science Foundation of China(31991210);Pinduoduo-China Agricultural University Research Fund(PC2023A01003).
Wheat(Triticum aestivum)production is vital for global food security,providing energy and protein to mil-lions of people worldwide.Recent advancements in wheat research have led to significant increases in pro-duction...
关键词：WHEAT GENETICS GENOMICS yield quality stress tolerance disease resistance breeding 
Single-cell omics: experimental workflow, data analyses and applications被引量：1
《Science China(Life Sciences)》2025年第1期5-102,共98页Fengying Sun Haoyan Li Dongqing Sun Shaliu Fu Lei Gu Xin Shao Qinqin Wang Xin Dong Bin Duan Feiyang Xing Jun Wu Minmin Xiao Fangqing Zhao Jing-Dong J.Han Qi Liu Xiaohui Fan Chen Li Chenfei Wang Tieliu Shi 
supported by the National Natural Science Foundation of China(32130020,32025009,82030099,30700397,31970638,61572361,81973701,U23A20513,32222026,82373446);the National Key Research and Development Program of China(2021YFF1201200,2021YFF1200900,2022YFA1106000);the Shanghai Municipal Science and Technology Major Project(2017SHZDZX01);the Fundamental Research Funds for the Central Universities(20002150110,22120230292);Beihang University&Capital Medical University Plan(BHME-201904);the Special Fund of the Pediatric Medical Coordinated Development Center of Beijing Hospitals Authority(XTCX201809);the Cooperative Research Fund of the Affiliated Wuhu Hospital of East China Normal University(40500-20104-222400);the Fundamental Research Funds for the Central Universities(226-2024-00001);the Shanghai Municipal Science and Technology Commission“Science and Technology Innovation Action Plan”technical standard project(21DZ2201700);the Shanghai Municipal Science and Technology Commission“Science and Technology Innovation Action Plan”natural science foundation project(23ZR1435800);the Shanghai Natural Science Foundation Program(17ZR1449400);the Shanghai Artificial Intelligence Technology Standard Project(19DZ2200900);the Open Research Fund of Key Laboratory of Advanced Theory and Application in Statistics and Data Science-MOE,ECNU,Key Laboratory of MEA,Ministry of Education,ECNU.
Cells are the fundamental units of biological systems and exhibit unique development trajectories and molecular features.Our exploration of how the genomes orchestrate the formation and maintenance of each cell,and co...
关键词：single-cell sequencing genome EPIGENOME PROTEOMICS metabolomics multimodal spatial transcriptomics CRISPR screening 
iSalivaomicDB: A comprehensive saliva omics database for insects
《Insect Science》2024年第6期1998-2001,共4页Bo Zhang Longfei Chen Shan Xiao Cong Dang Fang Wang Qi Fang Xinhai Ye David W.Stanley Gongyin Ye 
supported by the Key Program of National Natural Science Foundation of China(31830074);the“Pioneer”and“Leading Goose”R&D Program of Zhejiang(No.2023C02030);the Program for Chinese Innovation Team in Key Areas of Science and Technology of the Ministry of Science and Technology of the People's Republic of China(2016RA4008)。
Dear Editor,Insect saliva is formed and secreted by the salivary gland,which is vital for various physiological processes,such as feeding and for viral transmission.More recently,omic approaches,such as transcriptomic...
关键词：VALUED INSIGHT REVEALING 
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