Traditional Chinese medicine and modern technology:Network pharmacology and omics sequencing in gastric cancer  

作　　者：Jessica Shapiro Gemmell Brandon Lucke-Wold 

机构地区：[1]College of Medicine,University of Florida,Gainesville,FL 32601,United States [2]Department of Neurosurgery,University of Florida,Gainesville,FL 32608,United States

出　　处：《World Journal of Gastrointestinal Oncology》2025年第3期38-43,共6页世界胃肠肿瘤学杂志(英文)

摘　　要：In this editorial,we comment on the article by Micucci et al published in the recent issue.We focus on the heterogenous nature of gastric cancer(GC)and the potential benefits of integrating traditional Chinese medicine(TCM)with the modern technology of network pharmacology(NP)and omics sequencing.GC is a heterogenous disease,as it incorporates several biochemical pathways that contribute to pathogenesis.TCM acknowledges the multifactorial,heterogenous nature of disease and utilizes an integrative approach to medicine.NP,a modern philosophy within drug development,integrates traditional knowledge of nutraceuticals and modern technologies to address the complex interactions of pathways within the body.Omics technologies,which is at the core of precision medicine,has allowed for this newfound principle of drug development.Metabolic pathways are better distinguished,leading to more targeted drug development.However,the use of omics technology needs to be employed to better characterize the subtypes of GC.This will allow TCM’s use of nutraceuticals in the application of NP to better target metabolic pathways that may aid in the prevention of GC as well as enhance treatment.

关 键 词：Gastric cancer Traditional Chinese medicine OMICS Network pharmacology NUTRACEUTICALS Precision medicine 

分 类 号：R73[医药卫生—肿瘤]