AXONS

作品数：75被引量：221H指数：7
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相关领域：医药卫生生物学更多>>
相关作者：孙文婧更多>>
相关机构：空军军医大学（第四军医大学）普渡大学更多>>
相关期刊：《Science Bulletin》《Bioactive Materials》《Neuroscience Bulletin》《眼科学报》更多>>
相关基金：国家自然科学基金国家重点基础研究发展计划国家高技术研究发展计划北京市自然科学基金更多>>
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Targeting Wallerian degeneration in glaucoma
《Neural Regeneration Research》2026年第2期693-694,共2页Melissa Jöe Pete A.Williams 
supported by St.Erik Eye Hospital philanthropic donations,Vetenskapsrådet 2022-00799(to PAW).
Neurodegenerative diseases account for a large and increasing health and economic burden worldwide.With an increasingly aged population,this burden is set to increase.Optic neuropathies make up a large proportion of n...
关键词：health burden neurodegenerative diseases aged population Wallerian degeneration GLAUCOMA vision loss economic burden retinal ganglion cells their axons 
Mechanism by which Rab5 promotes regeneration and functional recovery of zebrafish Mauthner axons
《Neural Regeneration Research》2025年第6期1816-1824,共9页Jiantao Cui Yueru Shen Zheng Song Dinggang Fan Bing Hu 
supported by the Research Funds of the Center for Advanced Interdisciplinary Science and Biomedicine of IHM,No.QYZD20220002;the National Natural Science Foundation of China,No.82071357;a grant from the Ministry of Science and Technology of China,No.2019YFA0405600 (all to BH)。
Rab5 is a GTPase protein that is involved in intracellular membrane trafficking. It functions by binding to various effector proteins and regulating cellular responses, including the formation of transport vesicles an...
关键词：axonal regeneration Mauthner cell nerve regeneration Rab5 ZEBRAFISH 
Metabolic reprogramming: a new option for the treatment of spinal cord injury
《Neural Regeneration Research》2025年第4期1042-1057,共16页Jiangjie Chen Jinyang Chen Chao Yu Kaishun Xia Biao Yang Ronghao Wang Yi Li Kesi Shi Yuang Zhang Haibin Xu Xuesong Zhang Jingkai Wang Qixin Chen Chengzhen Liang 
supported by the National Natural Science Foundation of China,No.82202681(to JW);the Natural Science Foundation of Zhejiang Province,Nos.LZ22H090003(to QC),LR23H060001(to CL).
Spinal cord injuries impose a notably economic burden on society,mainly because of the severe after-effects they cause.Despite the ongoing development of various therapies for spinal cord injuries,their effectiveness ...
关键词：AXONS GLYCOLYSIS metabolic reprogramming metabolism mitochondria neural regeneration NEUROPROTECTION oxidative phosphorylation spinal cord injury therapy 
NG2 Glia:The Guardians Against Prion‑induced Neurotoxicity Through Prostaglandin E2 Blockade
《Neuroscience Bulletin》2025年第3期539-542,共4页Shu Feng Emily Parker Timon Cheng‑Yi Liu Luodan Yang 
supported by the National Natural Science Foundation of China(32300959);a Guangzhou Scientific Research Grant(SL2024A04J00578);the SCNU Young Faculty Development Program(22KJ04).
Neuron glia antigen-2(NG2)glia,also known as oligodendrocyte precursor cells(OPCs),are essential for maintaining the normal function and structure of the central nervous system(CNS)due to their supportive role[1].Unde...
关键词：maintaining normal function structure myelin sheath axons oligodendrocyte precursor cells opcs receiving synaptic input neurons NEUROTOXICITY PRION central nervous system cns due ng glia 
Growth hormone promotes the reconstruction of injured axons in the hypothalamo-neurohypophyseal system
《Neural Regeneration Research》2024年第10期2249-2258,共10页Kai Li Zhanpeng Feng Zhiwei Xiong Jun Pan Mingfeng Zhou Weizhao Li Yichao Ou Guangsen Wu Mengjie Che Haodong Gong Junjie Peng Xingqin Wang Songtao Qi Junxiang Peng 
supported by the Guangdong Basic and Applied Basic Research Foundation,Nos.2021A1515011371 (to JP),2021A1515110290 (to YO),2020A1515110564 (to XW);2023A 1 515010150 (to MZ);Science and Technology Planning Project of Guangzhou,No.202102020977 (to ZF);the National Natural Science Foundation of China,Nos.82201516 (to YO) and 81900709 (to ZF);President Foundation of Nanfang Hospital,Southern Medical University,Nos.2019C001 (to MZ),2019C016 (to XW), 2021C045 (to YO)。
Previous studies have shown that growth hormone can regulate hypothalamic energy metabolism, stress, and hormone release. Therefore, growth hormone has great potential for treating hypothalamic injury. In this study, ...
关键词：arginine vasopressin growth hormone hypothalamo-neurohypophyseal system HYPOTHALAMUS injury insulin-like growth factor 1 OXYTOCIN regeneration 
Neutrophil peptide 1 accelerates the clearance of degenerative axons during Wallerian degeneration by activating macrophages after peripheral nerve crush injury被引量：3
《Neural Regeneration Research》2024年第8期1822-1827,共6页Yuhui Kou Yusong Yuan Qicheng Li Wenyong Xie Hailin Xu Na Han 
supported by the National Natural Science Foundation of China,No.32371048(to YK);the Peking University People’s Hospital Research and Development Funds,No.RDX2021-01(to YK);the Natural Science Foundation of Beijing,No.7222198(to NH)。
Macrophages play an important role in peripheral nerve regeneration,but the specific mechanism of regeneration is still unclear.Our preliminary findings indicated that neutrophil peptide 1 is an innate immune peptide ...
关键词：axonal debris inflammatory factors MACROPHAGES neutrophil peptide 1 peripheral nerve injury peripheral nerve regeneration RAW 264.7 cells sciatic nerve Wallerian degeneration 
Mapping of individual sensory nerve axons from digits to spinal cord with the transparent embedding solvent system被引量：2
《Cell Research》2024年第2期124-139,共16页Yating Yi Youqi Li Shiwen Zhang Yi Men Yuhong Wang Dian Jing Jiayi Ding Qingjie Zhu Zexi Chen Xingjun Chen Jun-Liszt Li Yilong Wang Jun Wang Hanchuan Peng Li Zhang Wenjing Luo Jian Q.Feng Yongwen He Woo-Ping Ge Hu Zhao 
supported by a startup fund from the Chinese Institute for Brain Research to H.Z.and W.-P.G.,the National Natural Science Foundation of China(82101059 to Y.Y.);the Research Funding from West China School/Hospital of Stomatology Sichuan University(RCDWJS2022-11 to Y.Y.).
Achieving uniform optical resolution for a large tissue sample is a major challenge for deep imaging.For conventional tissue clearing methods,loss of resolution and quality in deep regions is inevitable due to limited...
关键词：EMBEDDING TRANSPARENT DIGIT 
Mechanism of Universal Quantum Computation in the Brain
《Journal of Applied Mathematics and Physics》2024年第2期468-474,共7页Aman Chawla Salvatore Domenic Morgera 
In this paper, the authors extend [1] and provide more details of how the brain may act like a quantum computer. In particular, positing the difference between voltages on two axons as the environment for ions undergo...
关键词：AXONS Quantum computation Metric perturbation DECOHERENCE Time-coded information 
Trick or treat?Does cancer fool Schwann cells by mimicking axons to promote metastasis into nerves?
《Neural Regeneration Research》2023年第8期1727-1727,共1页Peter Arthur-Farraj 
funded by a Clinical Research Career Development Fellowship from the Wellcome Trust(UK),206634/Z/17/Z。
The Schwann cell reaction to nerve injury,termed the repair program,is crucial to successful nerve regeneration.Over the last decade,substantial advances have been made in elucidating the underlying molecular mechanis...
关键词：NERVES invasion METASTASIS 
Chx10+V2a interneurons in spinal motor regulation and spinal cord injury被引量：3
《Neural Regeneration Research》2023年第5期933-939,共7页Wen-Yuan Li Ling-Xiao Deng Feng-Guo Zhai Xiao-Yu Wang Zhi-Gang Li Ying Wang 
supported by the National Natural Science Foundation of China,No. 81870977 (to YW);the Natural Science Foundation of Heilongjiang Province of China,No. JQ2021H004 (to YW);PhD research foundation of Mudanjiang Medicine College,No. 2021-MYBSKY-039 (to WYL);Fundamental Research Funds for Heilongjiang Provincial Universities,No. 2021-KYYWF-0469 (to WYL)。
Chx10-expressing V2 a(Chx10+V2 a) spinal interneurons play a large role in the excitatory drive of motoneurons. Chemogenetic ablation studies have demonstrated the essential nature of Chx10+V2 a interneurons in the re...
关键词：AXONS central nervous system central pattern generator Chx10 differentiation INTERNEURONS locomotion motor neurons PROPRIOSPINAL spinal cord injuries therapy transcription factor transplantation V2a neuron 
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