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The complex role of protocadherin-19 in brain function:a focus on the oxytocin system: 《Neural Regeneration Research》2025年第11期3211-3212,共2页Sara Mazzoleni Marta Busnelli Silvia Bassani; supported by a grant from Telethon Foundation(grant No.GGP20056 to SB);The generation of Pcdh19 floxed mouse model was funded by Cariplo Foundation(grant No.2014-0972 to SB)。; Mutations in the protocadherin-19(PCDH19)gene(Xq22.1)cause the X-linked syndrome known as developmental and epileptic encephalopathy 9(DEE9,OMIM#300088)(Dibbens et al.,2008).DEE9 is characterized by early-onset cluste...; 关键词：EPILEPSY FUNCTION SYSTEM

Oxytocin ameliorates cognitive impairments by attenuating excitation/inhibition imbalance of neurotransmitters acting on parvalbumin interneurons in a mouse model of sepsisassociated encephalopathy: 《Journal of Biomedical Research》2025年第2期132-145,共14页Renqi Li Qiuting Zeng Muhuo Ji Yue Zhang Mingjie Mao Shanwu Feng Manlin Duan Zhiqiang Zhou; supported by grants from the general project of Nanjing Medical University Science and Technology Development Foundation (Grant No.NMUB20210112)。; Inflammation plays a crucial role in the initiation and progression of sepsis and induces alterations in brain neurotransmission, thereby contributing to the development of sepsis-associated encephalopathy(SAE).Parval...; 关键词：excitation/inhibition balance OXYTOCIN cognitive sepsis-associated encephalopathy

Oxytocin Alleviates Colitis and Colitis-Associated Colorectal Tumorigenesis via Noncanonical Fucosylation: 《Research》2025年第1期593-605,共13页Xia Wang Dawei Chen Mengnan Guo Yao Ning Mingze Geng Jing Guo Jiahui Gao Dong Zhao Yupeng Zhang Qianpeng Li Lixiang Li Shiyang Li Yanqing Li Xiaoran Xie Xiuli Zuo Jingxin Li; supported by the following grants:National Natural Science Foundation of China(82070551,82270570,32271172,and 82200584);China Postdoctoral Science Foundation(2022M721963);Taishan Scholars Program of Shandong Province,and the Natural Science Foundation of Shandong Province(ZR2021LSWO12).; Colon cancer is increasing worldwide and is commonly regarded as hormone independent,yet recent reports have implicated sex hormones in its development.Nevertheless,the role of hormones from the hypothalamus-hypophysi...; 关键词：sex hormones colon cancer FUCOSYLATION Colorectal Cancer generated mice OXYTOCIN COLITIS

Growth hormone promotes the reconstruction of injured axons in the hypothalamo-neurohypophyseal system: 《Neural Regeneration Research》2024年第10期2249-2258,共10页Kai Li Zhanpeng Feng Zhiwei Xiong Jun Pan Mingfeng Zhou Weizhao Li Yichao Ou Guangsen Wu Mengjie Che Haodong Gong Junjie Peng Xingqin Wang Songtao Qi Junxiang Peng; supported by the Guangdong Basic and Applied Basic Research Foundation,Nos.2021A1515011371 (to JP),2021A1515110290 (to YO),2020A1515110564 (to XW);2023A 1 515010150 (to MZ);Science and Technology Planning Project of Guangzhou,No.202102020977 (to ZF);the National Natural Science Foundation of China,Nos.82201516 (to YO) and 81900709 (to ZF);President Foundation of Nanfang Hospital,Southern Medical University,Nos.2019C001 (to MZ),2019C016 (to XW), 2021C045 (to YO)。; Previous studies have shown that growth hormone can regulate hypothalamic energy metabolism, stress, and hormone release. Therefore, growth hormone has great potential for treating hypothalamic injury. In this study, ...; 关键词：arginine vasopressin growth hormone hypothalamo-neurohypophyseal system HYPOTHALAMUS injury insulin-like growth factor 1 OXYTOCIN regeneration

Therapeutic Potential of Thunbergia laurifolia L.Extract in Gestational Diabetes Mellitus:Insights from a Rat Model: 《Chinese Journal of Integrative Medicine》2024年第9期788-798,共11页Sasitorn Kerdsuknirund Arreeya Kosinan Panida Khunkaewla Pakanit Kupittayanant Ratchadaporn Oonsivilai Pattama Tongdee Porntip Nimkuntod Susan Wray Sajeera Kupittayanant; Supported by the Institute of Research and Development,Suranaree University of Technology(Ph.D.Scholarship,No.SUT-PhD/14/2554)。; Objective:To assess the effects of Thunbergia laurifolia L.extract(TLE)on gestational diabetes mellitus(GDM)in a rat model.Methods:Thunbergia laurifolin L.leaves were subjected to ethanolic extraction.In vivo study,50...; 关键词：MYOMETRIUM gestational diabetes mellitus TOCOLYTIC OXYTOCIN Thunbergia laurifolia L.

The Function of Oxytocin in Memory —A General Review of Oxytocin’s Effect on Memory: 《World Journal of Neuroscience》2023年第4期192-209,共18页Fan Gao; Introduction: While oxytocin (OT) is widely recognized for its pivotal role in reproductive behavior and the formation of social bonds, there remains a significant gap in our understanding of its potential influence o...; 关键词：OXYTOCIN Learning and Memory Long-Term Memory Short-Term Memory EMOTION

Wenjing Zhitong recipe exhibits potential anti-primary dysmenorrhea properties by inhibiting COX2 and PKC signaling pathway in rats induced by estradiol benzoate and oxytocin: 《Journal of Traditional Chinese Medical Sciences》2023年第3期296-309,共14页Jialin Li Xiaoyao Liu Mei Jiang Yantong Xu Chunguo Wang Yujie Hu Song Yang Jian Gao Weiling Wang Ting Wang; supported by Beijing University of Chinese Medicine(1000061224003);National Natural Science Foundation of China(81903766,81900603,82104440)。; Objective:To explore the effect and mechanism of action of the Wenjing Zhitong recipe(WZR)in primary dysmenorrhea(PD)treatment.Methods:Uterine contractions were induced by estradiol benzoate and oxytocin in a PD model...; 关键词：Wenjing zhitong recipe Primary dysmenorrhea Network pharmacology PGF2a PKC system

Comparative Study of the Efficacy of Misoprostol and Oxytocin Im in the Prevention of Post-Partum haemorrhage in a Low-Resource Setting: 《Open Journal of Obstetrics and Gynecology》2023年第5期983-996,共14页De-Joseph Kakisingi Mibi Olivier Nyakio Éloge Ilunga Mbaya Dieudonné Kakusu Marie Constance Nguru Musese Julien Bwama Botalatala Omari Mukanga Tina Ndala Kasongo Gabrio Zacchè Dieudonné Sengeyi Mushengezi Amani Mary T. White Mary Joséphine O’Sullivan; Background: In developing countries, postpartum hemorrhage is responsible for 30% of maternal deaths. Although the World Health Organization recommends the use of oxytocin for the prevention of postpartum hemorrhage, ...; 关键词：MISOPROSTOL OXYTOCIN Postpartum Hemorrhage Saint-Vincent Hospital

Lighting up Oxytocin Neurons to Nurture the Brain: 《Neuroscience Bulletin》2023年第5期866-868,共3页Fang Zhou Junqiang Zheng Han Xu; supported by grants from the National Natural Science Foundation of China(32125018 and 32071005);the Fundamental Research Funds for the Central Universities,the MOE Frontiers Science Center for Brain Science&Brain-Machine Integration of Zhejiang University,and Innovative Research Team of High-level Local Universities in Shanghai(SHSMU-ZDCX20211102).; The sensory system develops earlier than the systems responsible for higher brain functions such as language and cognition[1].Moreover,sensory experiences in early life are critical for the development of the brain.Ho...; 关键词：NEONATAL neural SENSORY

Oxytocin Abuse and Postpartum Hemorrhage: 《Open Journal of Obstetrics and Gynecology》2022年第12期1320-1327,共8页Loutfi Guennoun Abdelmounaim Mohammed Khouchoua Nouha Nhiri Naouale Biougnache Mohamed Adnane Rhaidouni Ouassila Laouji Fatima El Hadraoui Safae Habib Rabbi Omar El Ayoubi Omar Alaoui Samir Messnan Said Lafkir; Among the most consolidated dogmas in obstetrics, we have the essential role of oxytocin during: labor by regulating, consolidating uterine contractions, by supporting the expulsive efforts of the patient during child...; 关键词：OXYTOCIN ANTISPASMODIC Postpartum Hemorrhage Uterine Inertia Dynamic Dystocia Cesarean Section Abnormal Fetal Heart Rate

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