COLITIS

作品数：702被引量：3506H指数：26
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相关机构：华中科技大学第二军医大学东南大学中国医科大学更多>>
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Sturgeon cartilage-derived chondroitin sulfate exhibited anti-inflammatory activity against dextran sulfate sodium-induced colitis via modification of gut microbiota
《Food Science and Human Wellness》2025年第4期1239-1250,共12页Ruiyun Wu Zixin Han Zhenyu Wang Pinglan Li Nan Shang 
funded by grants from Beijing Fishery Innovation Team Project(BAIC07-2023-13);National Natural Science Foundation of China(32201994)。
Chondroitin sulfate(CS)is one of the main bioactive compounds in animal cartilage.In this study,the antiinflammatory activity of sturgeon-derived chondroitin sulfate(SCS)was evaluated in the dextran sulfate sodium(DSS...
关键词：Sturgeon cartilage Chondroitin sulfate Anti-inflammatory activity Dextran sulfate sodium-induced colitis Gut microbiota 
Malic enzyme 3 mediated the effects of malic acid on intestinal redox status and feed efficiency in broilers
《Journal of Animal Science and Biotechnology》2025年第2期913-930,共18页Hongfeng Jiang Genghui Li Xue Yang Xiaohua Feng Penglin Li Huisi Yang Demin Cai Qingyan Jiang Gang Shu 
supported by the local innovative and research teams project of Guangdong province(2019BT02N630);national key research and development program(2022YFD1300401);Double first-class discipline promoting project(2023B10564001);National Natural Science Foundation of China(32272954);Natural Science Foundation of Guangdong Province,China(2024A1515013131).
Background Intestinal oxidative stress serves as an endogenous host defense against the gut microbiota by increas-ing energy expenditure and therefore decreasing feed efficiency(FE).Several systems coordinately regula...
关键词：COLITIS Feed efficiency Malic acid Malic enzyme 3 Redox 
Silkworm pupa peptide ameliorates dextran sulfate sodium-induced colitis by enhancing gut barriers and modifying gut flora
《Food Science and Human Wellness》2025年第2期758-768,共11页Yaxi Zhou Diandian Wang Hao Duan Shiqi Zhou Jinhong Guo Yu Guo Jian Zhao Wenjie Yan 
supported by the National Key Research and Development Program of China(2023YFF1103802)。
The anti-inflammatory properties of silkworm pupa peptide(SPP)have been recognized for their potential benefits in colitis treatment.However,the underlying mechanism of SPP in colitis animal models remains unclear.The...
关键词：Silkworm pupa peptide Ulcerative colitis Intestinal barrier Gut flora Short-chain fatty acids 
Pu-erh tea partly improved liver cholesterol metabolism disorders in colitis mice via the gut-liver axis
《Food Science and Human Wellness》2025年第2期706-718,共13页Shanshan Hu Zhiyuan Lin Sibo Zhao Bowen Zhang Liyong Luo Liang Zeng 
supported by the National Natural Science Foundation of China funded project(32172627);Chongqing Modern Tea Technology System for Efficient Agriculture in Mountainous Areas 2022[8];the Germplasm Creation Research Program of Southwest University。
Pu-erh tea has been shown to reduce gut inflammation in dextran sulfate sodium(DSS)-induced mice.Also,we found abnormal liver cholesterol metabolism in DSS-induced mice.However,it's not clear how Pu-erh tea improves D...
关键词：Pu-erh tea Dextran sulfate sodium(DSS)-induced colitis Liver cholesterol metabolism disorders Bile acid metabolism Gut microbes 
Oxytocin Alleviates Colitis and Colitis-Associated Colorectal Tumorigenesis via Noncanonical Fucosylation
《Research》2025年第1期593-605,共13页Xia Wang Dawei Chen Mengnan Guo Yao Ning Mingze Geng Jing Guo Jiahui Gao Dong Zhao Yupeng Zhang Qianpeng Li Lixiang Li Shiyang Li Yanqing Li Xiaoran Xie Xiuli Zuo Jingxin Li 
supported by the following grants:National Natural Science Foundation of China(82070551,82270570,32271172,and 82200584);China Postdoctoral Science Foundation(2022M721963);Taishan Scholars Program of Shandong Province,and the Natural Science Foundation of Shandong Province(ZR2021LSWO12).
Colon cancer is increasing worldwide and is commonly regarded as hormone independent,yet recent reports have implicated sex hormones in its development.Nevertheless,the role of hormones from the hypothalamus-hypophysi...
关键词：sex hormones colon cancer FUCOSYLATION Colorectal Cancer generated mice OXYTOCIN COLITIS 
Network pharmacology and molecular docking based study on the potential mechanism of the treatment of colitis by Solanum nigrum Linn.
《Journal of Polyphenols》2025年第1期20-31,共12页Bingxin Zhang Zhennan Meng Kexin Huang Ziqi Sun Xiaoshu Zhang 
The purpose of this study was to characterize the chemical components of the extract of Solanum Nigrum Linn.(SNL),by LC-MS/MS,and to identify 33 compounds by positive and negative total ion flow maps.Network pharmacol...
关键词：LC-MS/MS ulcerative colitis network pharmacology molecular docking Solanum Nigrum Linn 
Septic shock due to cytomegalovirus colitis associated with rituximab use:A case report
《World Journal of Virology》2025年第1期118-123,共6页Siddharth Patel Jordan Jay Prutha Pathak Mc Anto Antony Mrudula Thiriveedi 
BACKGROUND Cytomegalovirus(CMV)infections can cause significant morbidity and mortality in immunocompromised individuals.CMV targets dysfunctional lymphocytes.Chronic rituximab(RTX)therapy can cause B-lymphocyte dysfu...
关键词：Cytomegalovirus colitis Rituximab use Immunocompromised status Septic shock PANCYTOPENIA Case report 
A derivative of tanshinone IIA and salviadione,15a,inhibits inflammation and alleviates DSS-induced colitis in mice by direct binding and inhibition of RIPK2
《Acta Pharmacologica Sinica》2025年第3期672-686,共15页Cheng-hong Hu Yue Chen Tian-yang Jin Zhe Wang Bo Jin Jing Liao Chun-yong Ding Ao Zhang Wei-yang Tang Ling-xi Zhang Lei-yu Xu Fang-min Ning Guang Liang Xiao-hong Wei Yi Wang 
supported by the Key Scientific Research Project of Wenzhou City(ZY2021021 to YW);the National Natural Science Foundation of China(82361138563 to YW).
Inflammatory bowel diseases(IBDs)are chronic inflammatory conditions primarily affecting the gastrointestinal tract.Previous studies established the role of the NF-κB signaling pathway in the development of IBDs,sugg...
关键词：inflammatory bowel diseases COLITIS tanshinone lIA and salviadione derivatives molecular target RIPK2 
Mesalazine alleviated the symptoms of spontaneous colitis in interleukin-10 knockout mice by regulating the STAT3/NF-κB signaling pathway
《World Journal of Gastroenterology》2025年第7期88-97,共10页Qian Chen Ya-Li Zhang Yong-Quan Shi Lie Zheng 
Supported by Xi’an Science and Technology Plan Project,No.23YXYJ0162;Shaanxi Province Traditional Chinese Medicine Research and Innovation Talent Plan Project,No.TZKN-CXRC-16;Project of Shaanxi Administration of Traditional Chinese Medicine,No.SZYKJCYC-2025-JC-010;Shaanxi Province Key Research and Development Plan Project-Social Development Field,No.S2025-YF-YBSF-0391;the Science and Technology Innovation Cultivation Program of Longhua Hospital affiliated to Shanghai University of Chinese Medicine,No.YD202220。
BACKGROUND Excessive endoplasmic reticulum(ER)stress in intestinal epithelial cells can lead to damage to the intestinal mucosal barrier,activate the signal transducer and activator of transcription 3(STAT3)/nuclear f...
关键词：MESALAZINE Ulcerative colitis Interleukin-10-/-mice Signal transducer and activator of transcription 3/nuclear factor kappa B signaling pathway Endoplasmic reticulum stress Inflammatory bowel disease 
Hollow cerium nanoparticles synthesized by one-step method for multienzyme activity to reduce colitis in mice
《World Journal of Gastroenterology》2025年第5期94-104,共11页Lin Mi Kai Zhang Jian-Xia Ma Jian-Feng Yao Yi-Li Tong Zhi-Jun Bao 
BACKGROUND Inflammatory bowel disease(IBD)is a common chronic intestinal inflammatory disease.High oxidative stress is a treatment target for IBD.Cerium oxide(CeO2)nanomaterials as nanozymes with antioxidant activity ...
关键词：Inflammatory bowel disease Nanozymes Hollow cerium nanoparticles One-step method Cerium oxide biosafety 
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