FIRING

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SETD3-mediated histidine methylation of MCM7 regulates DNA replication by facilitating chromatin loading of MCM
《Science China(Life Sciences)》2025年第3期793-808,共16页Hongguo Duan Shuang Wang Wen-Jie Shu Yongjia Tong Hai-Zhen Long Guohong Li Hai-Ning Du Meng-Jie Zhao 
supported by the National Key Research and Development program of China(2023YF0913403);the National Natural Science Foundation of China(32200584,31971231);the Fundamental Research Funds for the Central Universities(2042022dx0003,2042022kf1048);the China Postdoctoral Science Foundation(2021M702526).
The minichromosome maintenance complex(MCM)DNA helicase is an important replicative factor during DNA replication.The proper chromatin loading of MCM is a key step to ensure replication initiation during S phase.Becau...
关键词：histidine methylation SETD3 DNA replication MCM replication origin firing 
Physical mechanisms of human brain functions
《Quantitative Biology》2025年第1期1-27,共27页Zonghua Liu 
National Natural Science Foundation of China,Grant/Award Numbers:11835003,12175070;STI2030-Major Projects,Grant/Award Number:2021ZD0202600。
In recent years,exploring the physical mechanisms of brain functions has been a hot topic in the fields of nonlinear dynamics and complex networks,and many important achievements have been made,mainly based on the cha...
关键词：chimera states eigenmode analysis network synchronization remote firing propagation remote synchronization 
Calcium channels caught in peripheral glia’s tug-of-war on axon regeneration in Drosophila
《Neural Regeneration Research》2025年第2期475-476,共2页Jackson Powell Tobias Steinschaden Rose Horowitz Yuanquan Song 
Neural damage or degeneration is at the crux of many diseases,and treatment of these diseases will require the development of therapeutics to enhance and guide neural regeneration.Both intrinsic and extrinsic factors ...
关键词：DEGENERATION FIRING SYSTEM 
Transforming growth factor-beta 1 enhances discharge activity of cortical neurons
《Neural Regeneration Research》2025年第2期548-556,共9页Zhihui Ren Tian Li Xueer Liu Zelin Zhang Xiaoxuan Chen Weiqiang Chen Kangsheng Li Jiangtao Sheng 
supported by the Natural Science Foundation of Guangdong Province,Nos.2019A1515010649(to WC),2022A1515012044(to JS);the China Postdoctoral Science Foundation,No.2018M633091(to JS).
Transforming growth factor-beta 1(TGF-β1)has been extensively studied for its pleiotropic effects on central nervous system diseases.The neuroprotective or neurotoxic effects of TGF-β1 in specific brain areas may de...
关键词：central nervous system cortical neurons ERK firing properties JNK Nav1.3 p38 transforming growth factor-beta 1 traumatic brain injury voltage-gated sodium currents 
Influences of short-term and long-term plasticity of memristive synapse on firing activity of neuronal network
《Chinese Physics B》2024年第12期487-496,共10页Zhi-Jun Li Jing Zhang 
Project supported by the National Natural Science Foundations of China(Grant Nos.62171401 and 62071411)。
Synaptic plasticity can greatly affect the firing behavior of neural networks,and it specifically refers to changes in the strength,morphology,and function of synaptic connections.In this paper,a novel memristor model...
关键词：synaptic plasticity memristive synapse electromagnetic radiation hidden attractor phase synchronization 
Millennia-Old Celadon-Firing Technique Reignites Passion for Porcelain
《Women of China》2024年第11期56-59,共4页Lei Jingjing Interviewees 
Longquan,a historical and cultural city in East China's Zhejiang Province,is known throughout the world for the production of celadon porcelains.Longquan celadon,with a history of more than l,700 years,is a type of gr...
关键词：UNESCO renowned THROUGHOUT 
Experimental and numerical investigation of iron ore pellet firing using coupled CFD-DEM method
《Particuology》2024年第10期75-86,共12页Hafez Amani Eskandar Keshavarz Alamdari Mostafa Keshavarz Moraveji Bernhard Peters 
support from the Ministry of Science,Research and Technology(MSRT)of Iran[grant number:99-4109].
Iron ore pellets are the main feedstock in ironmaking processes. While extensive research has addressed numerical modeling of the iron ore pellet induration process, little effort has been made to describe the intrica...
关键词：CFD-DEM Heatandmass transfer Ironorepellets Powderand pelletsize Modeling 
Low-firing and temperature stability regulation of tri-rutile MgTa_(2)O_(6)microwave dielectric ceramics
《International Journal of Minerals,Metallurgy and Materials》2024年第8期1935-1943,共9页Chengzhi Xu Hongyu Yang Hongcheng Yang Linzhuang Xing Yuan Wang Zhimin Li Enzhu Li Guorui Zhao 
This study is supported by the National Key Research and Development Program of China(No.2022YFB2807405);the Qinchuangyuan Citing High-level Innovation and Entrepreneurship Talent Projects(No.QCYRCXM-2022-40);the National Natural Science Foundation of China(Nos.U2341263 and 62371366);Open project of Yunnan Precious Metals Laboratory Co.,Ltd(No.YPML-2023050246);Innovation Capability Support Program of Shaanxi,China(Nos.2023-CX-PT-30 and 2022TD-28).
A glass frit containing Li_(2)O-MgO-ZnO-B_(2)O_(3)-SiO_(2)component was used to explore the low-temperature sintering behaviors and microwave dielectric characteristics of tri-rutile MgTa_(2)O_(6)ceramics in this stud...
关键词：MgTa_(2)O_(6) CERAMIC microwave dielectric characteristics glass 
Multi-Stage Multidisciplinary Design Optimization Method for Enhancing Complete Artillery Internal Ballistic Firing Performance
《Computer Modeling in Engineering & Sciences》2024年第7期793-819,共27页Jipeng Xie Guolai Yang Liqun Wang Lei Li 
supported by the“National Natural Science Foundation of China”(Grant Nos.52105106,52305155);the“Jiangsu Province Natural Science Foundation”(Grant Nos.BK20210342,BK20230904);the“Young Elite Scientists Sponsorship Programby CAST”(Grant No.2023JCJQQT061).
To enhance the comprehensive performance of artillery internal ballistics—encompassing power,accuracy,and service life—this study proposed a multi-stage multidisciplinary design optimization(MS-MDO)method.First,the ...
关键词：ARTILLERY internal ballistics dynamics multi-stage optimization multi-disciplinary design optimization collaborative optimization 
Impaired Spatial Firing Representations of Neurons in the Medial Entorhinal Cortex of the Epileptic Rat Using Microelectrode Arrays
《Research》2024年第2期541-552,共12页Zhaojie Xu Fan Mo Gucheng Yang Penghui Fan Botao Lu Wei Liang Fanli Kong Luyi Jing Wei Xu Juntao Liu Mixia Wang Yirong Wu Xinxia Cai 
funded by the National Natural Science Foundation of China(nos.L2224042,T2293731,62121003,61960206012,61973292,62171434,61975206,and 61971400);the Frontier Interdisciplinary Project of the Chinese Academy of Sciences(no.XK2022XXC003);the National Key Research and Development Program of China(nos.2022YFC2402501 and 2022YFB3205602);Major Program of Scientific and Technical Innovation 2030(no.2021ZD02016030);the Scientific Instrument Developing Project of the Chinese Academy of Sciences(no.GJJSTD20210004).
Epilepsy severely impairs the cognitive behavior of patients.It remains unclear whether epilepsy-induced cognitive impairment is associated with neuronal activities in the medial entorhinal cortex(MEC),a region known ...
关键词：EPILEPSY IMPAIRED INVOLVEMENT 
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