GERM-FREE

作品数：20被引量：118H指数：7
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相关领域：医药卫生更多>>
相关作者：孙静吴梦葛良鹏丁玉春杜震宇更多>>
相关机构：重庆市畜牧科学院华东师范大学重庆医科大学更多>>
相关期刊：《Biophysics Reports》《Insect Science》《Animal Nutrition》《Journal of Animal Science and Biotechnology》更多>>
相关基金：国家自然科学基金国家重点基础研究发展计划更多>>
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Drosophila melanogaster A rapid and reproducible method for generating germ-free
《Biophysics Reports》2024年第6期364-368,共5页An-Qi Li Sha-Sha Li Hui-Lin Li Lan-Lan Zhong Guo-Bao Tian Xin-Yuan Zhao Qiao-Ping Wang 
funded by the National Natural Science Foundation of China(31970934);the Fundamental Research Funds for the Central Universities(20ykzd18)to Q.P.W。
Microbial communities exert a profound influence on various facets of animal behavior and physiology,making the comprehension of their interactions with hosts or the environment essential.Drosophila melanogaster,a wid...
关键词：AXENIC GERM-FREE MICROBIOTA DROSOPHILA Protocol 
Germ-free, carefree: injured skin uses IL-24 to kick-start repair independent of pathogen-recognition被引量：1
《Signal Transduction and Targeted Therapy》2023年第11期5129-5131,共3页Ruben A.Ferrer Marta Torregrossa Sandra Franz 
Skin injury releases damage-associated molecular patterns(DAMPs)represented by tissue-components and intracellular contents as well as changes in the levels of certain molecules and metabolites that signal the“non-ho...
关键词：wound HOMEOSTASIS release 
The direct and gut microbiota-mediated effects of dietary bile acids on the improvement of gut barriers in largemouth bass(Micropterus salmoides)被引量：4
《Animal Nutrition》2023年第3期32-42,共11页Rui Xia Qingshuang Zhang Dongmei Xia Qiang Hao Qianwen Ding Chao Ran Yalin Yang Aizhi Cao Zhen Zhang Zhigang Zhou 
funded by National Natural Science Foundation of China(NSFC 32061133004 and 31925038)。
Fish gut barrier damage under intensive culture model is a significant concern for aquaculture industry.This study aimed to investigate the effects of bile acids(BAs)on gut barriers in Micropterus salmoides.A germ-fre...
关键词：Bile acids Gut barrier Gut microbiota Largemouth bass Germ-free zebrafish 
Dynamics of the intestinal bacterial community in black soldier fly larval guts and its influence on insect growth and development被引量：7
《Insect Science》2023年第4期947-963,共17页Xin-Yu Li Cheng Mei Xing-Yu Luo Dilinuer Wulamu Shuai Zhan Yong-Ping Huang Hong Yang 
supported by the National Natural Science Foundation of China(31670004);the Fundamental Research Funds for the Central Universities,Central China Normal University(KJ02072019-0383 and CCNU20CG005).
Black soldier fly(BSF),Hermetia illucens(Diptera:Stratiomyidae),is a promi-nent insect for the bioconversion of various organic wastes.As a saprotrophic insect,the BSF inhabits microbe-rich environments.However,the in...
关键词：bacterial isolates germ-free BSF larvae growth and development Hermetia illucens promotive effects 
Characterizing the influence of gut microbiota on host tryptophan metabolism with germ-free pigs被引量：1
《Animal Nutrition》2022年第4期190-200,共11页Bingnan Liu Dongming Yu Jing Sun Xiaoyan Wu Zhongquan Xin Baichuan Deng Lijuan Fan Jian Fu Liangpeng Ge Wenkai Ren 
National Key R&D Program of China(2021YFD1300700);Laboratory of Lingnan Modern Agriculture Project(NT2021005)。
Intestinal microbes are closely associated with host health,depending on metabolic crosstalk between the microbiota and host.Tryptophan metabolism is one of the best examples of metabolic crosstalk between intestinal ...
关键词：Germ-free pig Gut microbiota TRYPTOPHAN INDOLE KYNURENINE 
Short-chain fatty acids can improve lipid and glucose metabolism independently of the pig gut microbiota被引量：12
《Journal of Animal Science and Biotechnology》2021年第4期1414-1427,共14页Hua Zhou Bing Yu Jing Sun Zuohua Liu Hong Chen Liangpeng Ge Daiwen Chen 
study was supported by National Natural Science Foundation of China(31730091);the National Key Research and Development Program of China(2017YFD0500503).
Background:Previous studies have shown that exogenous short-chain fatty acids(SCFAs)introduction attenuated the body fat deposition in conventional mice and pigs.However,limited studies have evaluated the effects of e...
关键词：GERM-FREE Glucose metabolism Lipid metabolism Pig model Short-chain fatty acids 
Investigation of the metabolites of five major constituents from Berberis amurensis in normal and pseudo germ-free rats被引量：3
《Chinese Journal of Natural Medicines》2021年第10期758-771,共14页LIAO Cui-Ping LIU Xing-Chao DONG Shi-Qi AN Ming ZHAO Lu ZHANG Ai-Jie LIU Jian-Feng HOU Wen-Bin FAN Hui-Rong LIU Chang-Xiao 
supported by the National Key R&D Program of China(No.2018YFC1708203);the Non-profit Central Research Institute Fund of Chinese Academy of Medical Sciences(No.2018PT35031);the Drug Innovation Major Project(No.2018ZX09711001-002-002);the Major Science and Technology Project of Inner Mongolia Autonomous Region(No.2019ZD004).
Berberis amurensis(Berberidaceae)is a traditional Chinese medicine,which is often used to treat hypertension,inflammation,dysentery and enteritis.It contains alkaloids,mainly including berberine,berbamine,magnoflorine...
关键词：Berberis amurensis BERBERIDACEAE Pseudo germ-free rat Intestinal flora UPLC/Q-TOF-MS/MS 
Carrageenan oligosaccharides and associated carrageenan-degrading bacteria induce intestinal inflammation in germ-free mice被引量：1
《Journal of Genetics and Genomics》2021年第9期815-824,共10页Yeshi Yin Miaomiao Li Weizhong Gu Benhua Zeng Wei Liu Liying Zhu Xionge Pi Donald A.Primerano Hongwei D.Yu Hong Wei Guangli Yu Xin Wang 
supported by National Natural Science Foundation of China(NSFC,31870106);supported by National Natural Science Foundation of China(NSFC,81991522);Key Research&Development of Zhejiang Province(2018C02048);State Key Laboratory for Managing Biotic and Chemical Threats to the Quality and Safety of Agroproducts(2010DS0024-ZZ006);the National Science and Technology Major Project for Significant New Drug Development(2018ZX09735004);Taishan Scholar Climbing Project(TSPD20210304);supported by Distinguished Young Scholars of Hunan Natural Science Foundation(2020JJ2016);supported by NIGMS R44GM113545 and P20GM103434;supported by NIGMS WV-INBRE P20GM103434。
Carrageenans(CGNs)are widely used in foods and pharmaceuticals although their safety remains controversial.To investigate the effects of CGNs and CGN-degrading bacteria in the human colon,we screened for CGN degradati...
关键词：CARRAGEENANS Carrageenan oligosaccharides Oligosaccharide degrading bacteria Intestinal inflammatory Germ-free mouse 
Gut microbiota absence and transplantation affect growth and intestinal functions:An investigation in a germ-free pig model被引量：8
《Animal Nutrition》2021年第2期295-304,共10页Hua Zhou Jing Sun Bing Yu Zuohua Liu Hong Chen Jun He Xiangbing Mao Ping Zheng Jie Yu Junqiu Luo Yuheng Luo Hui Yan Liangpeng Ge Daiwen Chen 
National Natural Science Foundation of China(31730091);the National Key Research and Development Program of China(2017YFD0500503).
This study was conducted to investigate host-microbiota interactions and explore the effects of maternal gut microbiota transplantation on the growth and intestinal functions of newborns in a germ-free(GF)pig model.Tw...
关键词：GERM-FREE Host microbiota interaction Maternal gut microbiota transplantation Growth performance Intestinal function Pig model 
Preclinical safety,effectiveness evaluation,and screening of functional bacteria for fecal microbiota transplantation based on germ-free animals
《World Journal of Meta-Analysis》2021年第6期496-504,共9页Ya-Peng Yang Xue-Ying Zhang Bo-Ta Cui Hang Zhang Zhi-Feng Wu Xiang Tan Wei Cheng Xi Zhu Fa-Ming Zhang Huan-Long Qin Hong Wei 
Fecal microbiota transplantation(FMT),also known as fecal bacterial therapy,is a treatment option that can quickly reconstruct the normal composition of intestinal microbes,and it has a good therapeutic effect on Clos...
关键词：Fecal microbiota transplantation EFFECTIVENESS Safety Germ-fee animals Functional bacteria 
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