Cycloheptatriene is a privileged structural motif present in many bioactive compounds,pharmaceutical agents and natural products,especially in a large number of core structures of sesquiterpenoids.Herein,a mild and ef...
the Qingdao Marine Science and Technology Center(No.2022QNLM030003-2);the Fundamental Research Funds for the Central Universities,Taishan Scholar Program of Shandong Province(No.tsqn202103152);National Natural Science Foundation of China(No.22171251) for financial support。
The first total synthesis of(+)-taberdicatine B and(+)-tabernabovine B has been accomplished in 10steps with 26.9% overall yield and 15 steps with 7.3% overall yield,respectively.The prominent features of this efficie...
National Natural Science Foundation of China(32372830 and 31972528).
Background Weaning stress-induced diarrhea is widely recognized as being associated with gut microbiota dysbio-sis.However,it has been challenging to clarify which specific intestinal microbiota and their metabolites ...
supported by the National Natural Science foundation of China(Nos.22225104,92356302,22071077,21975102).
Indole derivatives,especially bisindolylesters,have attracted intense attention due to their important applications in medicinal chemistry and organic synthesis.Here we develop a Lewis acid-catalyzed efficient and reg...
Support by the National Natural Science Foundation of China(Nos.22271244 and 22071211);the Hunan Provincial Natural Science Foundation of China(Nos.2023JJ40561 and 2022JJ40359);the Hunan Provincial Health Commission Foundation(B202313020111);Open Research Fund of School of Chemistry and Chemical Engineering,Henan Normal University(No.2022C02)is gratefully acknowledged.
The Pictet-Spengler/transamination cascade reaction enables modular synthesis of marinoquinoline analoguesthrough three-component indole ring-expansion/cyclization in the manner of novel N1–C2 cleavage of indoles.Thi...
support from the Leading Innovative and Entrepreneur Team Introduction Program of Zhejiang(2022R01007);the NSFC(22171082,22201253);the Start-up Research Grant from Zhejiang Normal University;the Shanghai Frontiers Science Center of Optogenetic Techniques for Cell Metabolism.
We report a palladium-catalyzed asymmetric[4+4]cycloaddition reaction between 2-alkylidenetrimethylene carbonate and electron-deficient indole-2,3-quinodimethanes(IQDMs).This reaction features exclusive regioselectivi...
the National Natural Science Foundation of China(22001211);the Key Research and Development Program of Shaanxi Province(2023YBGY-454);Shaanxi Fundamental Science Research Project for Chemistry&Biology(Grant No.22JHQ015)for financial support;This project is also supported by the Opening Project of Key Laboratory of Optoelectronic Chemical Materials and Devices of Ministry of Education,Jianghan University(No.JDGD-202208);the Fundamental Research Funds for the Central Universities.
Construction of helicenes by inducing heteroatoms has regarded as an effective strategy to enhance the chiroptical properties.We report a facile synthesis of a multiple helicene based on four indoles with two electron...
supported by the National Key Research and Development Program of China (2022YFB4101800);the National Natural Science Foundation of China (22231002);the Guangdong Basic and Applied Basic Research Foundation (2024B1515040027)。
Indole is a promising heteroarene in many natural products and pharmaceuticals;therefore, various synthetic methods for indole functionalizations have arisen in recent years. Herein, we report a Pd-catalyzed deoxygena...
The authors are grateful for financial support from the Doctoral Research Funds of Liaoning Petrochemical University(2019×JJ-006).
1-Butyl-3-methylimidazolium bromide-based ([Bmim]Br-based) deep eutectic solvents (DESs) can be used aseffective extractants for removing nitrogen compounds from fuel oil. Among the DESs studied, the combination of [B...
financial support from the Natural Science Foundation of Shanghai(20zR1405500).
Herein,we report rhodium catalyzed N-arylation via addition of arylboronic acids to electron-deficientα-iminoesters which can be prepared in high efficiency by using easily accessible B-carbonyl esters.The reaction i...