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INFLAMMATORY: 作品数：1343被引量：5270H指数：26; 导出分析报告; 相关领域：医药卫生更多>>; 相关作者：王国春卢昕戚晓昆邹忠东王兴鹏更多>>; 相关机构：中日友好医院北京协和医院复旦大学温州医科大学更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金国家重点基础研究发展计划中国博士后科学基金湖北省自然科学基金更多>>

Secretome of polarized macrophages:potential for targeting inflammatory dynamics in spinal cord injury: 《Neural Regeneration Research》2025年第11期3231-3232,共2页Andreia Monteiro Susana Monteiro Nuno A.Silva; funded by national funds,through the Foundation for Science and Technology(FCT)-project UIDB/50026/2020,UIDP/50026/2020(to NAS),EXPL/MEDPAT/0931/2021(to SM);Financial support was provided by Prémios Santa Casa Neurociências-Prize Melo e Castro for Spinal Cord Injury Research(MC-18-2021);Wings For Life Spinal Cord Research Foundation(WFL-PT-14/23);"la Caixa"Foundation(HR23-00484)(to NAS);the FCT for the Scientific Employment Stimulus to NAS and SM(CEECIND/04794/2017 and CEECIND/01902/2017)。; Spinal cord injury(SCI)involves an initial traumatic phase,followed by secondary events such as ischemia,increased blood-spinal cord barrier permeability,ionic disruption,glutamate excitotoxicity,and metabolic alterat...; 关键词：alterations injury COMPANIES

Total adenosine deaminase cases as an inflammatory biomarker of pleural effusion syndrome: 《World Journal of Clinical Cases》2025年第19期14-23,共10页Bernardo Henrique Ferraz Maranhão Cyro Teixeira da Silva Junior Jorge Luiz Barillo Joeber Bernardo Soares Souza Patricia Siqueira Silva Roberto Stirbulov; BACKGROUND Although inflammatory diseases commonly affect the pleura and pleural space,their mechanisms of action remain unclear.The presence of several mediators emphasizes the concept of pleural inflammation.Adenosi...; 关键词：Pleural effusion BIOMARKER Adenosine deaminase INFLAMMATION transudate EXUDATE

YTHDF1 shapes immune-mediated hepatitis via regulating inflammatory cell recruitment and response: 《Genes & Diseases》2025年第3期550-566,共17页Hao Li Kailun Yu Xiandan Zhang Jiawen Li Huilong Hu Xusheng Deng Siyu Zeng Xiaoning Dong Junru Zhao Yongyou Zhang; supported by grants from the National Natural Science Foundation of China(No.81772539,81972238);the Fundamental Research Funds for the Central Universities of China-Xiamen University(No.20720180048).; Severe immune responses regulate the various clinical hepatic injuries, includingautoimmune hepatitis and acute viral hepatitis. N6-methyladenosine (m6A) modification is acrucial regulator of immunity and inflammation...; 关键词：Concanavalin A HEPATITIS Inflammatory response N6-methyladenine YTHDF1

Dynamics of inflammatory signals within the tumor microenvironment: 《World Journal of Experimental Medicine》2025年第2期24-39,共16页Hala Issa Lokjan Singh Kok-Song Lai Tina Parusheva-Borsitzky Shamshul Ansari; Tumor stroma,or tumor microenvironment(TME),has been in the spotlight during recent years for its role in tumor development,growth,and metastasis.It consists of a myriad of elements,including tumor-associated macropha...; 关键词：Inflammatory signals Tumor microenvironment CYTOKINES INTERLEUKINS Transforming growth factor

Shenzhuo formulation ameliorates diabetic nephropathy by regulating cytochrome P450-mediated arachidonic acid metabolism: 《World Journal of Diabetes》2025年第5期331-345,共15页Zhong-Yong Zhang Yu-Ming Wang Ning Wang Yuan-Song Wang Hui Zhang Duo Wang Li-Xin Wang Huan-Tian Cui Wei-Bo Wen Shu-Quan Lv Yong-Jun Cao; Supported by the Natural Science Foundation of Hebei Province Beijing-Tianjin-Hebei Basic Research Special Program,No.H2020110287;Key Laboratory for Diabetic Kidney Disease Syndrome and Treatment of the Traditional Chinese Medicine Administration of Hebei Province,No.7[2024];Yuansong Wang National Famous Traditional Chinese Medicine Expert Heritage Studio,No.3[2024];Hebei Key Laboratory of Integrated Traditional Chinese and Western Medicine for Diabetes and Its Complications,No.SZX2020015;Jiangsu Province Chinese Medicine Science and Technology Development Program Project,No.YB2020065.; BACKGROUND Diabetic nephropathy(DN)is a major complication of diabetes,marked by progressive renal damage and an inflammatory response.Although research has investigated the pathological mechanisms underlying DN,effec...; 关键词：Diabetic nephropathy Shenzhuo formulation TRANSCRIPTOMIC METABOLOMIC Cytochrome P450 Arachidonic acid metabolic INFLAMMATORY Oxidative stress

MicroRNA-122-5p is upregulated in diabetic foot ulcers and decelerates the transition from the inflammatory to the proliferative stage: 《World Journal of Diabetes》2025年第4期236-251,共16页Mei-Jie Yuan He-Chen Huang Hong-Shuo Shi Xiao-Ming Hu Zhuo Zhao Yu-Qi Chen Wei-Jing Fan Jian Sun Guo-Bin Liu; Supported by the National Natural Science Foundation of China,No.82274528.; BACKGROUND Shifting from the inflammatory to the proliferative phase represents a pivotal step during managing diabetic foot ulcers(DFUs);however,existing medical interventions remain insufficient.MicroRNAs(miRs)highl...; 关键词：MicroRNA-122-5p Diabetic foot ulcer Wound healing INFLAMMATION FIBROSIS

Exosomal mediators in sepsis and inflammatory organ injury:unraveling the role of exosomes in intercellular crosstalk and organ dysfunction: 《Military Medical Research》2025年第2期264-284,共21页Ting Gong You-Tan Liu Jie Fan; USA National Institutes of Health Grant(R01-HL-139547,to JF);USA VA Grants(1I01BX004838 and IK6BX004211,to JF);National Natural Science Foundation of China(82002087,to TG);Shenzhen Science and Technology Program(JCYJ20210324134602008,to TG)。; Sepsis,a severe systemic inflammatory response to infection,remains a leading cause of morbidity and mortality worldwide.Exosomes,as mediators of intercellular communication,play a pivotal role in the pathogenesis of ...; 关键词：SEPSIS EXOSOMES Intercellular crosstalk Inflammation Biomarkers

Prognostic value of the preoperative systemic immune-inflammation nutritional index in patients with gastric cancer: 《World Journal of Clinical Oncology》2025年第4期130-141,共12页Li-Jing Wang Cai-Lu Lei Ting-An Wang Zhi-Feng Lin Shi-Jie Feng Tao Wei Yan-Qin Li Meng-Ru Shen Yan Li Liu-Feng Liao; Supported by the Scientific Research Project of Hospital Pharmacy of Guangxi Pharmaceutical Association in 2022,No.GXYXH1-202202.; BACKGROUND Gastric cancer(GC)is the fifth most common cancer and the third leading cause of cancer-related deaths in China.Many patients with GC frequently experience symptoms related to the disease,including anorexia...; 关键词：Systemic immune-inflammatory-nutritional index Prognostic nutritional index Nutritional risk index Gastric cancer Prognosis

Aging-related inflammatory and metabolic disorder in the novel mutation of colony-stimulating factor-1 receptor(csf1r)^(P853T/+)in CsF1R-microglial encephalopathy: 《Genes & Diseases》2025年第2期45-47,共3页Xiaohong Wang Yanli Wang Tianlin Jiang Jiwei Jiang Linlin Wang Shiyi Yang Mengfan Sun Yuan Zhang Ziyan Jia Wenyi Li Qiwei Ren Cuicui Zhang Jianjian Liu Yinwei Zhu Min Zhao Shirui Jiang Huiying Zhang Jinglong Chen Jun Xu; supported by the National Natural Science Foundation of China (No.82071187,81870821,81501135,and 81471215);the National Key Research and Development Program of China (No.2021YFC2500100,2021YFC2500103);the Beijing Youth Talent Team Support Program (China) (No.2018000021223TD08);Science and Technology Program of Guangzhou (China) (No.202201020343).; CSF1R-microglial encephalopathy(CME)is a rare dementia with rapid development of cognitive impairment.The main clinical features of CME are progressive cognitive impairment,motor dysfunction,and neuropsychiatric sympt...; 关键词：ENCEPHALOPATHY DEGENERATION IMPAIRMENT

Intricacy of Crohn’s disease:Incongruity between diagnostic modalities and histopathologic assessment: 《World Journal of Gastrointestinal Endoscopy》2025年第4期1-5,共5页Hai-Ming Fang; Supported by the Anhui Provincial Natural Science Foundation,No.2308085MH242;the Basic and Clinical Cooperative Research Promotion Program of Anhui Medical University,No.021xkjT023;Anhui Medical University Foundation Project,No.2022xkj175.; Crohn’s disease(CD)is a chronic and recurrent inflammatory condition.Histologic healing is associated with better outcomes in CD,while less is known regarding the assessment of histological condition.Recently,a study...; 关键词：Crohn’s disease Transmural inflammatory Histopathological scoring system ENDOSCOPY Cross-sectional imaging techniques

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