ENDOCYTOSIS

作品数：161被引量：419H指数：10
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New aspects of a small GTPase RAB35 in brain development and function
《Neural Regeneration Research》2025年第7期1971-1980,共10页Ikuko Maejima Ken Sato 
supported by the Japan Society for the Promotion of Science KAKENHI(grant Nos.23K05678 to IM,19H05711 and 20H00466 to KS);the Joint Research Program of Institute for Molecular and Cellular Regulation,Gunma University(to KS)。
In eukaryotic cells,organelles in the secretory,lysosomal,and endocytic pathways actively exchange biological materials with each other through intracellular membrane trafficking,which is the process of transporting t...
关键词：ENDOCYTOSIS ENDOSOMES hippocampal development neurodegenerative diseases RAB35 
SARS-CoV-2 Inhibits Exo-Endocytosis and Enhances Short-Term Depression at a Central Synapse
《Neuroscience Bulletin》2025年第1期165-171,共7页Jiawei Hu Yuhan Zhang Qingzhuo Liu Jiaqi Hu Yichen Ru Lu Zhang Lixin Xie Lei Xue 
sponsored by the National Key Research&Development Program of China(2022YFC3602700 and 2022YFC3602702);the Science and Technology Innovation 2030-Brain Science and Brain-Inspired Intelligence Project(2021ZD0201301);the National Natural Science Foundation of China(32170688 and 82172109);Shanghai Municipal Science and Technology Major Project(2018SHZDZX01),and ZJLab.
Dear Editor,SARS-CoV-2 is the virus that caused the COVID-19 pandemic,leading to more than 774 million cases and 7,037,007 deaths by March 2024(World Health Organization,http://covid19.who.int/).Despite effective trea...
关键词：TRAVEL SPITE fatigue 
Vesicular transport-related genes in Diaphorina citri are involved in the process of Candidatus Liberibacter asiaticus infection
《Journal of Integrative Agriculture》2024年第12期4136-4146,共11页Yingzhe Yuan Tao Peng Aijun Huang Jun He Chenyang Yuan Tianyuan Liu Long Yi Xuejin Cui Xuefeng Wang Changyong Zhou 
supported by grants from the National Key Research and Development Program of China(2021YFD1400800);the National Natural Science Foundation of China(U23A0196 and 32160625);the Innovation Research 2035 Pilot Plan of Southwest University,China(SWU-5331000008);the Special Fund for Youth Team of Southwest University,China(SWUXJLJ202310);the Science and Technology Project of Jiangxi Province,China(20225BCJ22005)。
Asian citrus psyllid(ACP,Diaphorina citri)is the major vector of Candidatus Liberibacter asiaticus(CLas),which is a bacterial pathogen causing the devastating citrus Huanglongbing(HLB)disease.Diaphorina citri is known...
关键词：HUANGLONGBING ENDOCYTOSIS vesicular trafficking CLas acquisition 
The Constituent-Dependent Translocation Mechanism for PM_(2.5) to Travel through the Olfactory Pathway
《Environment & Health》2024年第12期856-864,共9页Sheng Wei Ting Xu Miao Cao Huan Wang Yiqun Song Daqiang Yin 
supported by the National Natural Science Foundation of China(22236006,22076146,and 22036001)。
The neurotoxic risk of PM_(2.5) is of worldwide concern,but the pathways through which PM_(2.5) gets to the central nervous system are still under debate.The olfactory pathway provides a promising shortcut to the brai...
关键词：particulate matter olfactory system central nervous system ENDOCYTOSIS vesicle transportation 
Amphipathicity mediated endocytosis of mesoporous silica nanoparticles with tunable frameworks
《Nano Research》2024年第9期8350-8359,共10页Runfeng Lin Tiancong Zhao Liang Chen Minchao Liu Hongyue Yu Ruicong Wang Minjia Yuan Xiaomin Li Dongyuan Zhao 
supported by the National Natural Science Foundation of China(Nos.22075049,22305042,22305041,21875043,22088101,21905052,and 51961145403);the National Key R&D Program of China(No.2018YFA0209401);the Key Basic Research Program of Science and Technology Commission of Shanghai Municipality(No.22JC1410200);the Natural Science Foundation of Shanghai(Nos.22ZR1478900 and 20490710600);the Shanghai Science and Technology Innovation Action Plan Morning Star Project(Sail Special,Nos.20QA1401200,22YF1402200,and 23YF1401900);the Shanghai Pilot Program for Basic Research-Fudan University(No.22TQ004);the Fundamental Research Funds for the Central Universities(No.20720220010).
Due to the amphiphilic nature of phospholipids in the cell membrane,the amphipathicity of the nanomedicine plays a crucial role in the endocytosis.However,limited biological characterization methods restrict the study...
关键词：mesoporous silica nanoparticles mesoporous organosilica ENDOCYTOSIS cell membrane AMPHIPATHICITY 
STED Imaging of Vesicular Endocytosis in the Synapse
《Neuroscience Bulletin》2024年第9期1379-1395,共17页Shaoqin Hu Zhenli Xie Bianbian Wang Yang Chen Zexin Jing Ying Hao Jingyu Yao Xuanang Wu Jingxiao Huo Anqi Wei Yuhao Qin Nan Dong Chaowen Zheng Qian Song Jiangang Long Xinjiang Kang Changhe Wang Huadong Xu 
National Natural Science Foundation of China(32171233,81901308,81974203,32300819,31670843,32000704,21790390,and 21790394);Key Research and Development Program of Shaanxi Province of China(2023-ZDLSF-23);Natural Science Foundation of Shaanxi Province of China(2019JC-07,2020JQ-029,and 2023-JC-QN-0236);Natural Science Foundation of Sichuan Province of China(2020YJ0337 and 2020YJ0378);Sichuan Science and Technology Program(2022YFS0615);China Postdoctoral Science Foundation(2018M640972);Innovation Capability Support Program of Shaanxi Province,China(2021TD-37);The Shaanxi Postdoc Funding(2023BSHTBZZ15,2023BSHYDZZ39 and 2023BSHEDZZ67).
Endocytosis is a fundamental biological process that couples exocytosis to maintain the homeostasis of the plasma membrane and sustained neurotransmission.Super-resolution microscopy enables optical imaging of exocyto...
关键词：ENDOCYTOSIS STED imaging Synaptic vesicle Single-vesicle level 
Extracellular vesicles(EVs)’journey in recipient cells:from recognition to cargo release被引量：1
《Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)》2024年第8期633-655,共23页Huayuan XIANG Chenxuan BAO Qiaoqiao CHEN Qing GAO Nan WANG Qianqian GAO Lingxiang MAO 
supported by the National Natural Science Foundation of China(No.32070182);the Key Project of Jiangsu Commission of Health(No.ZD2021049);the Highlevel Talent Program at Affiliated Kunshan Hospital of Jiangsu University(No.gccrc2022002);the Suzhou Municipal Science and Technology Development Plan(No.SKYD2023002);the Suzhou Municipal Key Discipline Construction Project(No.SZXK202124);the Talent Research Project of Suzhou Health Talent Plan(No.GSWS2023005),China.
Extracellular vesicles(EVs)are nano-sized bilayer vesicles that are shed or secreted by virtually every cell type.A variety of biomolecules,including proteins,lipids,coding and non-coding RNAs,and mitochondrial DNA,ca...
关键词：Extracellular vesicle(EV) EXOSOME ENDOCYTOSIS Uptake RELEASE 
Expanding the horizons of targeted protein degradation:A non-small molecule perspective
《Acta Pharmaceutica Sinica B》2024年第6期2402-2427,共26页Xiaowei Huang Fengbo Wu Jing Ye Lian Wang Xiaoyun Wang Xiang Li Gu He 
supported by grants from the National Natural Science Foundation of China(22177084,82273559,82103757 and 82073473);the China Postdoctoral Science Foundation(2022M722283);PostDoctor Research Project,West China Hospital,Sichuan University(2023HXBH076,China);Sichuan Natural Science Foundation Project(2023NSFSC1554,China);the 1.3.5 Project for Disciplines of Excellence,West China Hospital,Sichuan University(ZYJC21036,China).
Targeted protein degradation(TPD)represented by proteolysis targeting chimeras(PROTACs)marks a significant stride in drug discovery.A plethora of innovative technologies inspired by PROTAC have not only revolutionized...
关键词：Targeted protein degradation Proteolysis targeting chimera ENDOCYTOSIS Autophagy Proximity-inducing modality Post-translational modification 
Aagab is required for zebrafish larval development by regulating neural activity
《Journal of Genetics and Genomics》2024年第6期630-641,共12页Shihui Ding Tursunjan Aziz Anming Meng Shunji Jia 
supported by the National Natural Science Foundation of China(#92254302,#32293202,#2019YFA0801400 to S.J.,and#31988101 to A.M.).
Clathrin-mediated endocytosis has been implicated in various physiological processes,including nutrient uptake,signal transduction,synaptic vesicle recycling,maintenance of cell polarity,and antigen presentation.Despi...
关键词：Aagab ENDOCYTOSIS Neural activity Synaptic transmitter release ZEBRAFISH 
Membrane vesicles derived from Streptococcus suis serotype 2 induce cell pyroptosis in endothelial cells via the NLRP3/Caspase-1/GSDMD pathway
《Journal of Integrative Agriculture》2024年第4期1338-1353,共16页Keda Shi Yan Li Minsheng Xu Kunli Zhang Hongchao Gou Chunling Li Shaolun Zhai 
supported by the National Natural Science Foundation of China(U22A20520);the Innovation Team Project of Modern Agricultural Industrial Technology System of Guangdong Province,China(2023KJ119);the Natural Science Foundation Program of Guangdong Province,China(2023A1515012206)。
Streptococcus suis serotype 2(S.suis 2)is a zoonotic pathogen that clinically causes severe swine and human infections(such as meningitis,endocarditis,and septicemia).In order to cause widespread diseases in different...
关键词：Streptococcus suis serotype 2 membrane vesicles ENDOCYTOSIS PYROPTOSIS NLRP3 inflammasomes mitochondrial damage endothelial cell 
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