funded Pudong New Area Health Commission (PW2022A-28);Neuroscience Innovation and Development Research Project (YXJL-2022-00351-0183).
Glioma is the most aggressive and incurable brain tumor.1 Anoikis is programed apoptosis in which cells are detached from the cellular matrix and suspended to death.2 It plays a critical role in cancer progression.Can...
supported by a Ningxia Reproductive Disease Clinical Medical Research Center Project(2023-LCYX003);Ningxia Hui Autonomous Region Natural Science Foundation Project(2022AAC03748);Ningxia Hui Autonomous Region Natural Science Foundation Project(2021AAC03523);Yinchuan Science and Technology Innovation Project(2023SF25);Basic research project of Yinchuan Maternal and Child Health Hospital(2022NYFYCX05);Basic research project of Yinchuan Maternal and Child Health Hospital(2023NYFYCX01).
Triple-negative breast cancer(TNBC)is an inherently heterogeneous malignancy at the biological and clinical levels,occupying around 15%of diagnosed breast cancer cases and being the most lethal breast cancer subtype t...
Supported by The Basic Research Joint Special General Project of Yunnan Provincial Local Universities(part),No.202301BA070001-029 and No.202301BA070001-044;Yunnan Province High-Level Scientific and Technological Talents and Innovation Team Selection Special-Young and Middle-aged Academic and Technical Leaders Reserve Talent Project,No.202405AC350067.
BACKGROUND According to study,anoikis-related genes(ARGs)have been demonstrated to play a significant impact in cirrhosis,a major disease threatening human health worldwide.AIM To investigate the relationship between ...
supported by the National Natural Science Foundation of China (81773064,31972973,32021005);National Youth 1000 Talents Plan;the Jiangsu Specially-Appointed Professor Program;Jiangsu Province Recruitment Plan for High-level,Innovative and Entrepreneurial Talents (Innovative Research Team);Collaborative Innovation Center of Food Safety and Quality Control in Jiangsu Province
Loss of susceptibility to anoikis signals is a crucial step in metastasis.Anoikis resistance therefore represents a promising adjuvant therapeutic target for cancer management.In this study,we have conducted a rationa...
funded by Tianjin University of Traditional Chinese Medicine Startup Funding to Yunfei Li,and supported by Open Projects Fund of Shandong Key Laboratory of Carbohydrate Chemistry and Glycobiology,Shandong University(No.2023CCG13,China);funded by National Natural Science Foundation of China(No.82074030).
Tumor metastasis,the apex of cancer progression,poses a formidable challenge in therapeutic endeavors.Circulating tumor cells(CTCs),resilient entities originating from primary tumors or their metastases,significantly ...
Long non-coding RNAs(lncRNAs)play an indispensable role in the occurrence and development of ovarian cancer(OC).However,the potential involvement of lncRNAs in the progression of OC is largely unknown.To investigate t...
This work was supported by the National Natural Science Foundation(82172594 and 82373046);the Hunan Graduate Research Innovation Project(CX20230318),China.
Objective:Osteosarcoma is a highly aggressive primary malignant bone tumor commonly seen in children and adolescents,with a poor prognosis.Anchorage-dependent cell death(anoikis)has been proven to be indispensable in ...
This work was supported by the National Natural Science Foundation of China(No.21807117);Hunan Provincial Natural Science Foundation of China(Nos.2022JJ20052 and 2021JJ30788);the Science and Technology Innovation Program of Hunan Province(No.2022RC1109);Central South University Innovation-Driven Research Programme(No.2023CXQD021).
Artificial cells are constructed from synthetic materials to imitate the biological functions of natural cells.By virtue of nanoengineering techniques,artificial cells with designed biomimetic functions provide altern...
supported by the National Nature Science Foundation of China(Grant Numbers 81072214,30371547);the National Key R&D Program of China(Grant Number 2016YFC1102603).
We analyzed RNA-sequencing(RNA-seq)and clinical data from head and neck squamous cell carcinoma(HNSCC)patients in The Cancer Genome Atlas(TCGA)Genomic Data Commons(GDC)portal to investigate the prognostic value of ano...
supported by the Science Foundation of Fujian Province of China(2019J01596).
Circulating tumor cells(CTCs)are neoplastic cells that are detached from primary tumors and enter circulation.Enumeration and characterization of CTCs are of significance in cancer diagnosis,prognosis,and treatment mo...