ANOIKIS

作品数:43被引量:150H指数:5
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相关领域:医药卫生生物学更多>>
相关作者:赵群朱振宇刘芝华马涧泉张绪森更多>>
相关机构:兰州大学中山医科大学中国医学科学院肿瘤医院承德医学院更多>>
相关期刊:《中华风湿病学杂志》《中南大学学报(医学版)》《Cancer Biology & Medicine》《Acta Biochimica et Biophysica Sinica》更多>>
相关基金:国家自然科学基金教育部“新世纪优秀人才支持计划”河北省自然科学基金河北省科技领军人才创新基金更多>>
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Anoikis-related gene signature associates with the immune infiltration and predicts the prognosis of glioma patients
《Genes & Diseases》2025年第2期117-120,共4页Jianghua Lin Junbao Wang Junmiao Zhao Xinyi Wu Leiyu Hao Xiao Tan Lixue Yang Lei-Lei Wu Yuyang Xia Xiaoling Zhang Kaijun Zhao Yu'e Liu 
funded Pudong New Area Health Commission (PW2022A-28);Neuroscience Innovation and Development Research Project (YXJL-2022-00351-0183).
Glioma is the most aggressive and incurable brain tumor.1 Anoikis is programed apoptosis in which cells are detached from the cellular matrix and suspended to death.2 It plays a critical role in cancer progression.Can...
关键词:METASTASIS Cancer PATIENTS 
Heterogeneity of anoikis in triple-negative breast cancer subtyping and therapeutic implications
《Genes & Diseases》2025年第1期114-117,共4页Kun Fang Suxiao Jiang Zhengjie Xu Meng Luo Changsheng Yan 
supported by a Ningxia Reproductive Disease Clinical Medical Research Center Project(2023-LCYX003);Ningxia Hui Autonomous Region Natural Science Foundation Project(2022AAC03748);Ningxia Hui Autonomous Region Natural Science Foundation Project(2021AAC03523);Yinchuan Science and Technology Innovation Project(2023SF25);Basic research project of Yinchuan Maternal and Child Health Hospital(2022NYFYCX05);Basic research project of Yinchuan Maternal and Child Health Hospital(2023NYFYCX01).
Triple-negative breast cancer(TNBC)is an inherently heterogeneous malignancy at the biological and clinical levels,occupying around 15%of diagnosed breast cancer cases and being the most lethal breast cancer subtype t...
关键词:BREAST cancer clinical 
Development and validation of biomarkers related to anoikis in liver cirrhosis based on bioinformatics analysis
《World Journal of Hepatology》2024年第11期1306-1320,共15页Jiang-Yan Luo Sheng Zheng Juan Yang Chi Ma Xiao-Ying Ma Xing-Xing Wang Xin-Nian Fu Xiao-Zhou Mao 
Supported by The Basic Research Joint Special General Project of Yunnan Provincial Local Universities(part),No.202301BA070001-029 and No.202301BA070001-044;Yunnan Province High-Level Scientific and Technological Talents and Innovation Team Selection Special-Young and Middle-aged Academic and Technical Leaders Reserve Talent Project,No.202405AC350067.
BACKGROUND According to study,anoikis-related genes(ARGs)have been demonstrated to play a significant impact in cirrhosis,a major disease threatening human health worldwide.AIM To investigate the relationship between ...
关键词:Anoikis-related genes CIRRHOSIS Machine learning BIOMARKER Therapeutic drugs BIOINFORMATICS Immune infiltration 
Apigenin is an anoikis sensitizer with strong anti-metastatic properties in experimental breast cancer
《Food Science and Human Wellness》2024年第4期2221-2233,共13页Ruijie Xu Zhijie Yao Hao Zhang Haitao Li Wei Chen 
supported by the National Natural Science Foundation of China (81773064,31972973,32021005);National Youth 1000 Talents Plan;the Jiangsu Specially-Appointed Professor Program;Jiangsu Province Recruitment Plan for High-level,Innovative and Entrepreneurial Talents (Innovative Research Team);Collaborative Innovation Center of Food Safety and Quality Control in Jiangsu Province
Loss of susceptibility to anoikis signals is a crucial step in metastasis.Anoikis resistance therefore represents a promising adjuvant therapeutic target for cancer management.In this study,we have conducted a rationa...
关键词:APIGENIN ANOIKIS Breast cancer metastasis Thromboxane A2 
Advancements in precision nanomedicine design targeting the anoikis-platelet interface of circulating tumor cells
《Acta Pharmaceutica Sinica B》2024年第8期3457-3475,共19页Manqing Tang Zhijie Zhang Ping Wang Feng Zhao Lin Miao Yuming Wang Yingpeng Li Yunfei Li Zhonggao Gao 
funded by Tianjin University of Traditional Chinese Medicine Startup Funding to Yunfei Li,and supported by Open Projects Fund of Shandong Key Laboratory of Carbohydrate Chemistry and Glycobiology,Shandong University(No.2023CCG13,China);funded by National Natural Science Foundation of China(No.82074030).
Tumor metastasis,the apex of cancer progression,poses a formidable challenge in therapeutic endeavors.Circulating tumor cells(CTCs),resilient entities originating from primary tumors or their metastases,significantly ...
关键词:CTCS ANOIKIS PLATELET Cancer stem cell Metastasis Platelet‒CTC interaction Platelet targeting NANOMEDICINES 
RAD51B-AS1 promotes the malignant biological behavior of ovarian cancer through upregulation of RAD51B
《Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)》2024年第7期581-593,共13页Xinyi WEI Conghui WANG Sangsang TANG Qian YANG Zhangjin SHEN Jiawei ZHU Xiaodong CHENG Xinyu WANG Xing XIE Junfen XU Weiguo LU 
Long non-coding RNAs(lncRNAs)play an indispensable role in the occurrence and development of ovarian cancer(OC).However,the potential involvement of lncRNAs in the progression of OC is largely unknown.To investigate t...
关键词:Ovarian cancer(OC) Long non-coding RNA(LncRNA) Metastasis ANOIKIS 
Prognositic value of anoikis and tumor immune microenvironment-related gene in the treatment of osteosarcoma
《中南大学学报(医学版)》2024年第5期758-774,共17页WANG Dong DENG Qing PENG Yi TONG Zhaochen LI Zixin HUANG Liping ZENG Jin LI Jinsong MIAO Jinglei CHEN Shijie 
This work was supported by the National Natural Science Foundation(82172594 and 82373046);the Hunan Graduate Research Innovation Project(CX20230318),China.
Objective:Osteosarcoma is a highly aggressive primary malignant bone tumor commonly seen in children and adolescents,with a poor prognosis.Anchorage-dependent cell death(anoikis)has been proven to be indispensable in ...
关键词:ANOIKIS tumor immune microenvironment BIOINFORMATICS PROGNOSIS OSTEOSARCOMA 
Artificial Macrophage with Hierarchical Nanostructure for Biomimetic Reconstruction of Antitumor Immunity被引量:1
《Nano-Micro Letters》2023年第12期1-20,共20页Henan Zhao Renyu Liu Liqiang Wang Feiying Tang Wansong Chen You‑Nian Liu 
This work was supported by the National Natural Science Foundation of China(No.21807117);Hunan Provincial Natural Science Foundation of China(Nos.2022JJ20052 and 2021JJ30788);the Science and Technology Innovation Program of Hunan Province(No.2022RC1109);Central South University Innovation-Driven Research Programme(No.2023CXQD021).
Artificial cells are constructed from synthetic materials to imitate the biological functions of natural cells.By virtue of nanoengineering techniques,artificial cells with designed biomimetic functions provide altern...
关键词:Artificial macrophage Chemical messenger Hierarchical nanostructure ANOIKIS Antitumor immunotherap 
Comprehensive bioinformatics analysis and experimental validation:An anoikis-related gene prognostic model for targeted drug development in head and neck squamous cell carcinoma
《Oncology Research》2023年第5期715-752,共38页LIN QIU ANQI TAO XIAOQIAN SUN FEI LIU XIANPENG GE CUIYING LI 
supported by the National Nature Science Foundation of China(Grant Numbers 81072214,30371547);the National Key R&D Program of China(Grant Number 2016YFC1102603).
We analyzed RNA-sequencing(RNA-seq)and clinical data from head and neck squamous cell carcinoma(HNSCC)patients in The Cancer Genome Atlas(TCGA)Genomic Data Commons(GDC)portal to investigate the prognostic value of ano...
关键词:Head and neck squamous cell carcinoma ANOIKIS PROGNOSIS PROLIFERATION APOPTOSIS 
Circulating tumor cells: Biological features and survival mechanisms
《BIOCELL》2023年第8期1771-1781,共11页XIAOFENG LI JINYANG ZHENG JINFENG ZHU XIN HUANG HUANHUAN ZHU BINGDI CHEN 
supported by the Science Foundation of Fujian Province of China(2019J01596).
Circulating tumor cells(CTCs)are neoplastic cells that are detached from primary tumors and enter circulation.Enumeration and characterization of CTCs are of significance in cancer diagnosis,prognosis,and treatment mo...
关键词:ANOIKIS Circulating tumor cells HETEROGENEITY Immune evasion PLASTICITY 
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