AXON

作品数:202被引量:272H指数:8
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相关领域:医药卫生生物学更多>>
相关作者:杜尧江孙强熊韬和欣王维义更多>>
相关机构:中兴通讯股份有限公司北京中医药大学新加坡国立大学解放军第88医院更多>>
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相关基金:国家自然科学基金国家重点基础研究发展计划中国博士后科学基金福建省自然科学基金更多>>
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Is age-related myelinodegenerative change an initial risk factor of neurodegenerative diseases?
《Neural Regeneration Research》2026年第2期648-658,共11页Shuangchan Wu Jun Chen 
supported by grants from Guangdong Basic and Applied Basic Research Foundation,No.2021A1515110801(to SW);the National Natural Science Foundation of China,No.82301511(to SW);“Double First-Class”Construction Project of NPU,Nos.0515023GH0202320(to JC),0515023SH0201320(to JC)and 973 Program,No.2011CB504100(to JC).
Myelination,the continuous ensheathment of neuronal axons,is a lifelong process in the nervous system that is essential for the precise,temporospatial conduction of action potentials between neurons.Myelin also provid...
关键词:aging Alzheimer’s disease multiple sclerosis MYELIN myelin-axon metabolite crosstalk myelinodegeneration neurodegenerative disease OLIGODENDROCYTE Parkinson’s disease white matter 
Inhibition of the microglial voltage-gated proton channel 1 channel ameliorates diabetes-associated cognitive dysfunction by regulating axon demyelination
《World Journal of Psychiatry》2025年第3期288-301,共14页Chun-Yu Li Shu-Jun Zhang Jia-Lu Xu Yan Yang Zhi-Xuan Zeng De-Lin Ma 
Supported by the National Natural Science Foundation of China,No.82300894.
BACKGROUND Diabetes is associated with increased cognitive decline and dementia due to the loss of myelinated nerve fiber function,which is linked to oligodendrocyte dysfunction.The voltage-gated proton channel 1(Hv1)...
关键词:Diabetes Cognitive dysfunction Voltage-gated proton channel 1 Neuroinflammation Myelin regeneration 
Axonopathy Underlying Amyotrophic Lateral Sclerosis:Unraveling Complex Pathways and Therapeutic Insights
《Neuroscience Bulletin》2024年第11期1789-1810,共22页Tongshu Luan Qing Li Zhi Huang Yu Feng Duo Xu Yujie Zhou Yiqing Hu Tong Wang 
supported by the National Natural Science Foundation of China(32271001 and 31871036).
Amyotrophic Lateral Sclerosis(ALS)is a complex neurodegenerative disorder characterized by progressive axonopathy,jointly leading to the dying back of the motor neuron,disrupting both nerve signaling and motor control...
关键词:Amyotrophic lateral sclerosis Axonopathy Axon trafficking Protein aggregation Mitochondrial defect Neurotrophicfactor 
microRNA-2184 orchestrates Mauthner-cell axon regeneration in zebrafish via syt3 modulation
《Journal of Genetics and Genomics》2024年第9期911-921,共11页Xinghan Chen Yueru Shen Zheng Song Xinliang Wang Huaitong Yao Yuan Cai Zi-Ang Zhao Bing Hu 
supported by the Research Funds of the Center for Advanced Interdisciplinary Science and Biomedicine of IHM(QYZD20220002);the National Natural Science Foundation of China(82071357);the Ministry of Science and Technology of China(2019YFA0405600 to B.H.).
MicroRNAs(miRNAs)play a significant role in axon regeneration following spinal cord injury.However,the functions of numerous miRNAs in axon regeneration within the central nervous system(CNS)remain largely unexplored....
关键词:Axon regeneration Axon ablation miR-2184 syt3 Readily releasable pool 
Drosophila adhesion GPCR Remoulade regulates axon growth, branching, and guidance by modulating Rac1 GTPase
《Journal of Genetics and Genomics》2024年第4期458-461,共4页Xi Yang Changkun Pan Meitong Ye Jinshuo Liang Haoyang Cheng Qing Liang Shu Huang Jianshu Wang Hoi Yee Chow Haihuai He 
supported by research grants from the National Natural Science Foundation of China(31871461 and 31671510 to H.H.).
The assembly of neurons into complex circuits relies upon appropriate axonal navigation to distant targets.Although considerable progress has been made toward understanding the regulation of the guidance and branching...
关键词:branching MEDIAL AXON 
美国Axon Enterprise公司推出泰瑟10电击枪
《轻兵器》2024年第2期5-5,共1页
Axon Enterprise公司(前身为泰瑟国际公司)在之前泰瑟X26电击枪基础上推出泰瑟10电击枪,可连续发射10发电击弹,可大幅提升对犯罪嫌疑人的制服能力。相比于泰瑟X26,该电击枪在前部上方设有激光指示器和战术灯,这款1000流明的战术灯可以...
关键词:电击枪 激光指示器 安全距离 有效射程 犯罪嫌疑人 执法人员 推出 
The role of Down syndrome cell adhesion molecule in Down syndrome
《Medical Review》2024年第1期31-41,共11页Ty Hergenreder Tao Yang Bing Ye 
supported by funding from National Institutes of Health(R21NS094091);the Brain Research Foundation,and the Protein Folding Disease Initiative of the University of Michigan.
Down syndrome(DS)is caused by the presence of an extra copy of the entire or a portion of human chromosome 21(HSA21).This genomic alteration leads to elevated expression of numerous HSA21 genes,resulting in a variety ...
关键词:Down syndrome DSCAM NEURON AXON GABAergic synapse 
Chemokine platelet factor 4 accelerates peripheral nerve regeneration by regulating Schwann cell activation and axon elongation被引量:2
《Neural Regeneration Research》2024年第1期190-195,共6页Miao Gu Xiao Cheng Di Zhang Weiyan Wu Yi Cao Jianghong He 
supported by the National Natural Science Foundation of China,Nos.31730031,32130060;the National Natural Science Foundation of China,No.31971276(to JH);the Natural Science Foundation of Jiangsu Province,No.BK20202013(to XG);the Natural Science Foundation of Jiangsu Higher Education Institutions of China(Major Program),No.19KJA320005(to JH)。
Schwann cells in peripheral nerves react to traumatic nerve injury by attempting to grow and regenerate.Howeve r,it is unclear what factors play a role in this process.In this study,we searched a GEO database and foun...
关键词:axon elongation bioinformatic analysis cell migration cell proliferation dorsal root ganglia peripheral nerve regeneration peripheral nerve trauma platelet factor 4 rat sciatic nerve Schwann cells 
Axonal Conduction Velocity: A Computer Study
《Journal of Applied Mathematics and Physics》2024年第1期60-71,共12页Arthur D. Snider Aman Chawla Salvatore D. Morgera 
This paper derives rigorous statements concerning the propagation velocity of action potentials in axons. The authors use the Green’s function approach to approximate the action potential and find a relation between ...
关键词:NEURON AXON Action Potential Conduction Velocity INTERNODE 
A Study of Compound Action Potentials in Current-Coupled Tracts: the General Case
《Journal of Applied Mathematics and Physics》2023年第11期3345-3353,共9页Aman Chawla Salvatore Domenic Morgera 
In this paper, the authors investigate compound action potentials formed when the underlying tract's axons have current-mediated coupling amongst themselves, and no field-mediated coupling. The key finding of the pape...
关键词:Compound Action Potentials Current-Mediated Coupling Biophysically Inhomogeneous Axon Tracts Hodgkin-Huxley Equation Identical Axon Case 
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