supported by grants from Guangdong Basic and Applied Basic Research Foundation,No.2021A1515110801(to SW);the National Natural Science Foundation of China,No.82301511(to SW);“Double First-Class”Construction Project of NPU,Nos.0515023GH0202320(to JC),0515023SH0201320(to JC)and 973 Program,No.2011CB504100(to JC).
Myelination,the continuous ensheathment of neuronal axons,is a lifelong process in the nervous system that is essential for the precise,temporospatial conduction of action potentials between neurons.Myelin also provid...
Supported by the National Natural Science Foundation of China,No.82300894.
BACKGROUND Diabetes is associated with increased cognitive decline and dementia due to the loss of myelinated nerve fiber function,which is linked to oligodendrocyte dysfunction.The voltage-gated proton channel 1(Hv1)...
supported by the National Natural Science Foundation of China(32271001 and 31871036).
Amyotrophic Lateral Sclerosis(ALS)is a complex neurodegenerative disorder characterized by progressive axonopathy,jointly leading to the dying back of the motor neuron,disrupting both nerve signaling and motor control...
supported by the Research Funds of the Center for Advanced Interdisciplinary Science and Biomedicine of IHM(QYZD20220002);the National Natural Science Foundation of China(82071357);the Ministry of Science and Technology of China(2019YFA0405600 to B.H.).
MicroRNAs(miRNAs)play a significant role in axon regeneration following spinal cord injury.However,the functions of numerous miRNAs in axon regeneration within the central nervous system(CNS)remain largely unexplored....
supported by research grants from the National Natural Science Foundation of China(31871461 and 31671510 to H.H.).
The assembly of neurons into complex circuits relies upon appropriate axonal navigation to distant targets.Although considerable progress has been made toward understanding the regulation of the guidance and branching...
supported by funding from National Institutes of Health(R21NS094091);the Brain Research Foundation,and the Protein Folding Disease Initiative of the University of Michigan.
Down syndrome(DS)is caused by the presence of an extra copy of the entire or a portion of human chromosome 21(HSA21).This genomic alteration leads to elevated expression of numerous HSA21 genes,resulting in a variety ...
supported by the National Natural Science Foundation of China,Nos.31730031,32130060;the National Natural Science Foundation of China,No.31971276(to JH);the Natural Science Foundation of Jiangsu Province,No.BK20202013(to XG);the Natural Science Foundation of Jiangsu Higher Education Institutions of China(Major Program),No.19KJA320005(to JH)。
Schwann cells in peripheral nerves react to traumatic nerve injury by attempting to grow and regenerate.Howeve r,it is unclear what factors play a role in this process.In this study,we searched a GEO database and foun...
This paper derives rigorous statements concerning the propagation velocity of action potentials in axons. The authors use the Green’s function approach to approximate the action potential and find a relation between ...
In this paper, the authors investigate compound action potentials formed when the underlying tract's axons have current-mediated coupling amongst themselves, and no field-mediated coupling. The key finding of the pape...