云南高校图书馆联盟文献共享服务平台- PAEONOL

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A review on anti-inflammation activity of phenol compound paeonol: 《Journal of Polyphenols》2024年第3期106-116,共11页Weitao Zhong Hao Hu Jiaqing Cao Xinnan Li Xiangrong Zhang; Paeonol is a bioactive phenol present in Dioscorea japonica,Paeonia suff ruticosa and Paeonia lactiflora.It is the main active ingredient in the traditional Chinese medicines Mudanpi and Xu Changqing.Clinical applicat...; 关键词：PAEONOL INFLAMMATION molecular mechanisms gut microbes

Paeonol reduces microbial metabolite α-hydroxyisobutyric acid to alleviate the ROS/TXNIP/NLRP3 pathway-mediated endothelial inflammation in atherosclerosis mice被引量：3: 《Chinese Journal of Natural Medicines》2023年第10期759-774,共16页LIU Yarong WU Hongfei WANG Tian SHI Xiaoyan HE Hai HUANG Hanwen YANG Yulong DAI Min; supported by the National Natural Science Foundation of China(Nos.82104556 and 82174014);the Natural Science Foundation of Anhui Province,China(No.2108085-QH375);the National Project Cultivation Fund of Anhui University of Chinese Medicine(No.2021py01);the Talent Support Program of Anhui University of Chinese Medicine(No.2023rcyb027).; Gut microbiota dysbiosis is an avenue for the promotion of atherosclerosis(AS)and this effect is mediated partly via the circulating microbial metabolites.More microbial metabolites related to AS vascular inflammation...; 关键词：ATHEROSCLEROSIS PAEONOL a-Hydroxyisobutyric acid Gut microbiota Vascular endothelial inflammation

Coating Process of Paeonol Sustained Release Pills: 《Medicinal Plant》2023年第4期46-50,共5页Chunya ZHOU Huimin CHEN Liuliu LIU Yanlin HUANG Wenyu LUO Meijia CAI Fei HAN; Supported by National Natural Science Foundation of China(81560659);Science and Technology Research Project of Jiangxi Provincial Department of Education(GJJ201219,GJJ2200903);National College Students Innovation and Entrepreneurship Training Program(202210412022);Science and Technology Plan of Jiangxi Provincial Health Commission(202211411).; [Objectives] To study the coating process of paeonol sustained release pills by extrusion-spheronization method taking ethyl cellulose as the coating material. [Methods] Paeonol pills were made by Auari AW-95 Full Aut...; 关键词：PAEONOL Sustained release pills COATING Ethyl cellulose RELEASE

Protective effects of paeonol on LPS-induced macrophage RAW264.7 injury through TLR4/MAPK/NF-κB pathway: 《Journal of Hainan Medical University》2023年第3期22-28,共7页LIU Yu-long SUN Min LIU Ke YAN Gui-ming; Anhui Natural Science Foundation(2008085MH300)。; Objective:To study the protective effect of paeonol on LPS-induced inflammatory injury of macrophage RAW264.7 cells and its mechanism.Methods:Macrophage RAW264.7 cells were cultured and divided into blank group,LPS(1...; 关键词：PAEONOL Macrophage RAW264.7 TLR4 NF-κB

Investigation of paeonol-geniposide on acute alcoholic liver injury based on uniform design method: 《Journal of Hainan Medical University》2022年第24期25-31,共7页LIU Ke LIU Yu-long SUN Min LIU Ling-ling ZHANG Lu-ning YAN Gui-ming; Anhui Natural Science Foundation(No.2008085MH300)。; Objective:To explore the optimal ratio and compatibility effect of paeonol-geniposide combination on acute alcoholic liver injury by uniform design.Methods:Lieber-DeCarli alcoholic liquid feed was used to induce acute...; 关键词：PAEONOL GENIPOSIDE Alcoholic liver injury Uniform design Chinese medicine effective ingredient ratio

Prescription Design and Preparation Process of Paeonol Bead Popping Gum with Hypoglycemic Effect: 《Medicinal Plant》2022年第5期10-15,20,共7页Fuhao HU Yicheng WANG Hui YANG Yaokun XIONG Ming YANG Xinli LIANG Fei HAN; Supported by National Natural Science Foundation of China(81560659&81860771);Science and Technology Project of the Education Department of Jiangxi Province(GJJ201219);Students’Innovative Entrepreneurial Training Plan Program of Jiangxi University of Traditional Chinese Medicine(S202110412003,202010412025,202110412028);Doctoral Research Startup Fund of Jiangxi University of Traditional Chinese Medicine(2018WBZR011)。; [Objectives]To develop a paeonol bead popping gum with hypoglycemic effect.[Methods]The paeonol bead popping gum was prepared by the"two-step method",that is,the pill core was prepared by the guttate pill method,and t...; 关键词：PAEONOL Guttate pill Bead popping gum High performance liquid chromatography(HPLC)

Paeonol attenuated vascular fibrosis through regulating Treg/Th17 balance in gut microbiota-dependent manner被引量：7: 《中国药理学与毒理学杂志》2021年第10期736-737,共2页SHI Xiao-yan HUANG Han-wen ZHOU Min LIU Ya-rong WU Hong-fei DAI Min; National Natural Science Foundation of China(81773937)。; OBJECTIVE Atherosclerosis(AS)is a chronic inflammatory disease characterized by the accumulation of lipids,vascular fibrosis,and inflammation.Paeonol(Pae)is a natural phenolic compounds isolated from a traditional Chi...; 关键词：PAEONOL ATHEROSCLEROSIS gut microbiota Treg/Th17 balance vascular fibrosis

Paeonol regulates bile acid metabolism in ApoE^(-/-) mice and reduces atherosclerosis: 《China Medical Abstracts(Internal Medicine)》2021年第2期94-95,共2页HE Hai; Objective To explore the effect of paeonol(Pae)on the FXR-FGF15 signaling pathway by regulating the metabolism of bile acids in ApoE mice,thereby affecting lipid metabolism to play an anti-atherosclerotic effect.Metho...; 关键词：METABOLISM BILE effect.

Application of a quantitative ^1H NMR method for rapid extraction and determination of the content of paeonol in Cynanchum paniculatum被引量：3: 《Journal of Chinese Pharmaceutical Sciences》2020年第6期422-430,共9页Xuejiao Li Jianwei Dong Xiu Gao Guijun Li Junyou Shi Yanqing Zhang; Science and Technology Project of Yunnan Provincial Department of Science and Technology(Grant No.2018FD081);Yunnan Local Colleges Applied Basic Research Projects[Grant Nos.2019FH001-(109),2017FH001-092,2017FH001-094 and 2018FH001-019];Youth Research Foundation of Qujing Normal University in 2019(Grant No.2019QN004)。; Cynanchum paniculatum(Bunge) Kitagawa is usually used as an herbal medicine for treating many diseases. Paeonol is the main active component, and its content is the key indicator for quality control of C. paniculatum....; 关键词：Cynanchum paniculatum Quantitative ^1H NMR PAEONOL Quantitative determination

Effects of Paeonol Combined with Panax Notoginseng Saponins on Nrf2/ARE Pathway in Rats with Diabetic Cardiomyopathy: 《Medicinal Plant》2020年第1期37-39,43,共4页Yanfang FAN Xiaoli YAN Zhuoya JIA Kaihang SHI Kai CAO; [Objectives]To investigate whether paeonol(Pae)combined with panax notoginseng saponins(PNS)can protect the myocardium of rats with diabetic cardiomyopathy(DCM)through improving the antioxidant capacity of the rats by...; 关键词：PAEONOL PANAX notoginseng SAPONINS Diabetic CARDIOMYOPATHY MYOCARDIAL FIBROSIS Nrf2/ARE

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