SAPONINS

作品数：201被引量：572H指数：12
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Antibacterial,Antioxidant,Phytochemical Properties and GC-MS analyses of Mahareeb(Cymbopogon citratus)
《Food and Health》2025年第1期29-36,共8页Abdel Moniem Elhadi Sulieman Safa Mustafa Ibrahim Sohair A.Shommo Nosyba A.Ibrahim 
Background: Medical plants are a diverse group of commercially important plants thatprovide raw materials for pharmaceuticals, perfumes, flavors, and cosmetics. They includenumerous secondary metabolites and may conta...
关键词：PHOTOCHEMICAL PHARMACOKINETICS FLAVONOIDS GLYCOSIDES SAPONINS 
Saponins from Aralia taibaiensis protect against brain ischemia/reperfusion injuries by regulating the apelin/AMPK pathway
《Chinese Journal of Natural Medicines》2025年第3期299-310,共12页Zhengrong Li Yuwen Liu Kedi Liu Xingru Tao Naping Hu Wangting Li Jialin Duan 
supported by the National Science Foundation of China(No.81903832),the Key Research and Development Plan of Shaanxi Province(No.2022SF-182),the Fundamental Research Funds for the Central Universities(No.D5000210799);Shaanxi Provincial Traditional Chinese Medicine Administration"Double Chain Integration"Middle Youth Research and Innovation Team Project(No.2022-SLRH-LJ-007);Shanghai Science and Technology Innovation Action Plan(No.22S21902600).
Aralia taibaiensi,widely distributed in western China,particularly in the Qinba Mountains,has been utilized as a folk medicine for treating diabetes,gastropathy,rheumatism,and cardiovascular diseases.Saponins from A.t...
关键词：Aralia taibaiensis Apelin/apelin receptor Stroke P38 MAPK/ATF4 HIF-1A 
From steroidal glycoalkaloids to steroidal saponins:Biosynthesis and ecological role in the Solanum genus
《Molecular Plant》2025年第1期22-24,共3页Yan Li Jie Luo 
funded by grants from the National Natural Science Foundation of China(32100213);the Project of Sanya Yazhou Bay Science and Technology City(SCKJ-JYRC-2023-18);the Hainan Provincial Natural Science Foundation of China(222RC553,323RC423);the Hainan University Collaborative Innovation Center of Nanfan and High-Efficiency Tropical Agriculture(XTCX2022NYC09);the Hainan University Startup Fund(RZ2100003223).
Solanaceae plants produce two major classes of valuable steroid-derived specialized metabolites:steroidal glycoalkaloids(SGAs)and steroidal saponins(STSs)(Grzech et al.,2025).SGAs are crucial in plant defense despite ...
关键词：steroidal ALKALOIDS SAPONINS 
Regulation of histidine metabolism by Lactobacillus Reuteri mediates the pathogenesis and treatment of ischemic stroke
《Acta Pharmaceutica Sinica B》2025年第1期239-255,共17页Kangrui Hu Zhihao Zhou Haofeng Li Jijun Xiao Yun Shen Ke Ding Tingting Zhang Guangji Wang Haiping Hao Yan Liang 
supported by the National Natural Science Foundation of China(82274194);the Jiangsu Natural Science Funds(BK20211224,China);the Natural Science Foundation of Hebei Province(H_(2)020208025,H_(2)021208006,H_(2)021302001,C2021418001,China);the CAMS Innovation Fund for Medical Sciences(2021-I2M-5-011,China).
Increasing evidence has underscored the significance of post-stroke alterations along gutebrain axis,while its role in pathogenesis and treatment of ischemic stroke(IS)remains largely unexplored.This study aimed to el...
关键词：Ischemic stroke Inflammation Gut-brain axis Panaxnotoginseng saponins Lactobacillus reuteri Metabolomics HISTIDINE HISTAMINE 
Stem-leaf saponins of Panax notoginseng attenuate experimental Parkinson's disease progression in mice by inhibiting microglia-mediated neuroinflammation via P2Y2R/PI3K/AKT/NFκB signaling pathway
《Chinese Journal of Natural Medicines》2025年第1期43-53,共11页Hui Wu Chenyang Ni Yu Zhang Yingying Song Longchan Liu Fei Huang Hailian Shi Zhengtao Wang Xiaojun Wu 
supported by the Educational Commission of Shanghai in China(No.2021LK114);the Organizational Key Research and Development Program of Shanghai University of Traditional Chinese Medicine(No.2023YZZ02);the Xinglin Young Talent Program at Shanghai University of Traditional Chinese Medicine(No.A1-U17205010430)。
Stem-leaf saponins from Panax notoginseng(SLSP)comprise numerous PPD-type saponins with diverse pharmacological properties;however,their role in Parkinson's disease(PD),characterized by microglia-mediated neuroinflamm...
关键词：Stem-leaf saponins of Panax Notoginseng P2Y2 receptor NEUROINFLAMMATION MICROGLIA NFΚB 
Effects of steaming process on rare saponins and efficacy of Panax ginseng, Panax notoginseng and Panax quinquefolium被引量：1
《Chinese Herbal Medicines》2024年第4期521-528,共8页Wenjie Zhao Linlin Han Tao Li Jungjoon Lee Yuqing Zhao 
supported by the Higher Education Discipline Innovation Project (111 Project, D18012)。
The steamed Panax ginseng C. A. Mey., Panax notoginseng(Burk.) F. H. Chen, and Panax quinquefolium L. not only facilitate storage, but also increase the content of rare saponins and enhance their clinical application ...
关键词：Ginseng Radix et Rhizoma Notoginseng Radix et Rhizoma Panacis Quinquefolii Radix rare saponins steaming process 
Research progress on chemical diversity of saponins in Panax ginseng
《Chinese Herbal Medicines》2024年第4期529-547,共19页Xiaoyu Geng Jia Wang Yuwei Liu Linxuan Liu Xuekun Liu Yan Zhao Cuizhu Wang Jinping Liu 
funded by the Innovation Platform(base)and Talent Special Project(No.20210502005ZP);Key Research and Development Program of Jilin Province(No.20230204038YY,20240305052YY,20210204149YY)。
Saponins,the major bioactive components of Panax ginseng C.A.Mey.,are gradually emerging as research hotspots owing to the possession of various pharmacological activities.This review updates the ginsenosides list fro...
关键词：chemical diversity Panax ginseng C.A.Mey. pentacyclic triterpenoids SAPONINS tetracyclic triterpenoids 
Research progress on the anti-tumor effect of Codonopsis pilosula
《Pharmacology Discovery》2024年第3期22-29,共8页Xing-Lei Yin Ren-Jun Gu Xuan Han 
support of the National Natural Science Foundation of China(Grant No.82204696);the Natural Science Foundation project of Nanjing University of Chinese Medicine(Grant No.XPT82204696).
Currently,the mortality rate of malignant tumors ranks second globally,surpassed only by cardiovascular and cerebrovascular diseases.The treatment of malignant tumors poses a formidable challenge to both modern medici...
关键词：Codonopsis pilosula ANTI-TUMOR molecular mechanism Codonopsis polysaccharides ISOIMPERATORIN SAPONINS 
Insights into dammarane-type triterpenoid saponin biosynthesis from the telomere-totelomere genome of Gynostemma pentaphyllum
《Plant Communications》2024年第8期100-103,共4页Lingling Yun Chuyi Zhang Tongtong Liang Yu Tian Guoxu Ma Vincent Courdavault Sijie Sun Baiping Ma Ziqin Li Rucan Li Feng Cao Xiaofeng Shen Jianhe Wei Ying Li Baolin Guo Chao Sun 
supported by the Chinese Academy of Medical Sciences Innovation Fund for Medical Sciences(grant 2021-I2M-1-032).The funders had no role in the design of the study;the collection,analyses,or interpretation of data;the writing of the manuscript;or the decision to publish the results.
Dear Editor,Gynostemma pentaphyllum(Thunb.)Makino,a perennial climbing vine in the Cucurbitaceae family,has been widely used in traditional medicine for over 600 years(Blumert and Liu,1999).It serves as a valuable nat...
关键词：protective GYNOSTEMMA SAPONINS 
Glycomol: A pervasive tool for structure predication of natural saponin products basing on MS data被引量：1
《Journal of Pharmaceutical Analysis》2024年第7期1095-1098,共4页Daotong Zhao Chunguo Wang Hanyun Qu Qinling Rao Bingqing Shen Yinan Jiang Jiayu Gong Yumiao Wang Di Geng Rui Hong Tao Lu Qing Ni Xinqi Deng 
funded by the National Natural Science Foundation of China(Grant Nos.:82374076,and 82174354);National Key R&D Program of China(Grant No.:2023YFC3504100);Natural Science Foundation of Beijing(Grant No.:7244493);NSFC Cultivating Project of Institute of Chinese Materia Medica,China Academy of Chinese Medical Sciences(Grant No.:ZXKT23003);Young Elite Cultivating Project of Institute of Chinese Materia Medica,China Academy of Chinese Medical Sciences(Grant No.:ZZ17-YQ-023);Start-up Fund for New Scientific Researchers of China Academy of Chinese Medical Sciences(Grant No.:ZZ16-XRZ071).
Due to the multitudinous structural types of glycosylated components,accurate identification of glycosylation modifications and secondary metabolite structures in herbs remains a challenge for natural drug analysis an...
关键词：STRUCTURE AUXILIARY SAPONINS 
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