Guizhou Administration of TCM,Traditional Chinese medicine,Ethnic Medicine Science and Technology Research Special Project,Grant/Award Number:QZYY-2022-008;Subsidy Fund for Scientific Research and Innovation Exploration Project,National Natural Science Foundation of China of Guizhou University of Traditional Chinese Medicine,Grant/Award Number:2018YFC170810502;Science and Technology Fund Project of Guizhou Provincial Health Commission,Grant/Award Number:gzwkj2023-147;Development of animal models for drug discovery-brain diseases.National Research and Development Project of China,MOST,Grant/Award Number:2023YFF0724802.
Background:Qingyangshen(Cynanchum otophyllum C.K.Schneid)is a folk drug for treating depression and other mental disorders induced by social defeat stress.Neuroplasticity in the hippocampus is essential for the modula...
Background: Medical plants are a diverse group of commercially important plants thatprovide raw materials for pharmaceuticals, perfumes, flavors, and cosmetics. They includenumerous secondary metabolites and may conta...
supported by the National Key Research and Development Program of China(2022YFD1801600);National Natural Science Foundation of China(32230106).
Commensal enterococci with pathogenic potential often facilitate the growth of diverse pathogens,thereby exacerbating infections.However,there are few effective therapeutic strategies to prevent and intervene in enter...
supported by the National Key R&D Program of China(Nos.2022YFF1203005,2022YFC2303700);supported by the National Natural Science Foundation of China(Nos.81930097,82151223).
3-Deoxy-D-manno–oct-2-ulosonic acid(Kdo)is widely distributed in bacteria,and the synthesis of Kdocontaining oligosaccharides is important for the development of novel antibiotics and immunological agents.We have rec...
supported by the National Natural Science Foundation of China(32072159);Natural Science Foundation of Hainan Province(322QN338);Young Talent of Lifting Engineering for Science and Technology in Shandong,China(SDAST2021qt18);Qingdao Science and Technology Plan Key Research and Development Project(22-3-3-hygg-28-hy);Fundamental Research Funds for the Central Universities(202262003);Taishan Scholar Project of Shandong Province(tsqn202312099);Support Program for Youth Innovation Technology in Colleges and Universities of Shandong Province(2023KJ041)。
Laminarin oligosaccharides(LOSs)with a specific degree of polymerization prepared through the laminarin degradation via laminarinase present more significant nutritional functions and application values.Human intestin...
BACKGROUND Rheumatic immune diseases are a group of chronic inflammatory diseases charac-terized by joint and systemic multi-organ involvement,including rheumatoid arthritis,systemic lupus erythematosus,and Sjogren’s...
support from the National Natural Science Foundation of China(22071054,21871081);the Shanghai Frontiers Science Center of Optogenetic Techniques for Cell Metabolism(Shanghai Municipal Education Commission);the Taishan IndustrialExperts Program(tscx202312168))is ggratefully acknowledged.
Traditional protecting groups are often removed under harsh conditions with potentially hazardous reagents,thereby impeding the convenient synthesis of oligosaccharides and glycosides.Herein,we present to utilize the ...
supported by the National Natural Science Foundation of China(Nos.31960090 and 32160562);the State Key Laboratory of Food Science and Resources,Nanchang University(No.SKLF-ZZB-202129)。
Ten previously undescribed dammarane-type triterpenoid glycosides,cyclocarysaponins A–J(1–10),were isolated from the leaves of Cyclocarya paliurus(Batal.)Iljinskaja.The structures of these compounds were characteriz...
financially supported by the scientific and technological innovation project of the China Academy of Chinese Medical Sciences(Grant Nos.CI2021A03905,CI2021A04011,CI2021A04005);Quality and Technical Service Platform for Traditional Chinese Medicine Whole Industry Chain(Grant No.2022-230-221);China Agricultural Research SystemofMOF andMARA(CARS-21);the Key Project at Central Government Level:the ability establishment of sustainable use for valuable Chinese medicine resources(Grant No.2060302).
Background:Pleuropterus multiflorum Thunb.cv.“Heshouwu”(HSW)has been used as a classical material for both medicine and food in China for millennia.Recently,the cultivation region of HSW has shifted from Guangdong t...
financially supported by the National Natural Science Foundation of China(No.U1906213);the National Key Research and Development Program of China(No.2022YFC2804100)。
Four new cyclohexapeptides,pyridapeptides F–I(1–4),were isolated from the fermentation broth of marine sponge-derived Streptomyces sp.OUCMDZ-4539.The pyridapeptides F–H(1–3)are composed ofβ-hydroxyleucine,alanine...