Α2-MACROGLOBULIN

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Evaluating new biomarkers for diabetic nephropathy:Role ofα2-macroglobulin,podocalyxin,α-L-fucosidase,retinol-binding protein-4,and cystatin C被引量:1
《World Journal of Diabetes》2024年第6期1212-1225,共14页Jing-Jing Li Ru-La Sa Yu Zhang Zhao-Li Yan 
pported by the Natural Science Foundation of Inner Mongolia Autonomous Region,No.2022MS08057.
BACKGROUND The intricate relationship between type 2 diabetes mellitus(T2DM)and diabetic nephropathy(DN)presents a challenge in understanding the significance of various biomarkers in diagnosis.AIM To elucidate the ro...
关键词:Α2-MACROGLOBULIN Podocalysin Α-L-FUCOSIDASE Retinol binding protein-4 Cystatin C Diabetic nephropathy 
Roles of constitutively secreted extracellular chaperones in neuronal cell repair and regeneration
《Neural Regeneration Research》2023年第4期769-772,共4页Sandeep Satapathy Mark R.Wilson 
Protein quality control involves many processes that jointly act to regulate the expression, localization, turnover, and degradation of proteins, and has been highlighted in recent studies as critical to the different...
关键词:cell viability CLUSTERIN extracellular chaperones inflammation NEUROSERPIN protein misfolding TRANSTHYRETIN Α2-MACROGLOBULIN 
iTorin1—An Active Site Inhibitor of mTOR, Suppresses Prostate Cancer Cell Growth Induced by Activated α2M-Macroglobulin Ligation of Cell Surface GRP78
《Journal of Cancer Therapy》2013年第4期74-85,共12页Uma K. Misra Salvatore V. Pizzo 
In this study, we reported the effect of the ATP binding site competitive inhibitor Torin1 on activated α2-macroglobulin (α2M*)-induced cell proliferation and activation of mTORC1 and mTORC2 signaling in prostate ca...
关键词:Α2-MACROGLOBULIN Torin1 PROSTATE Cancer Cells Proliferation p-S6KT389 p-4EBP1 p-AktS473 Insulin 
Gene polymorphism of alpha-2 macroglobulin in patients with Parkinson's disease
《Journal of Medical Colleges of PLA(China)》2005年第3期175-177,共3页郝怡鑫 傅强 郭品娥 张建荣 沈茜 
Objective:To explore the relationship between polymorphism of α2-macroglobulin(A2M) gene and Parkinson’s disease(PD)in Han Nationality in Shanghai.Methods:The distributions of A2M gene polymorphism (a Val1000Ile in ...
关键词:Parkinson's disease α2-macroglobulin(A2M) GENE POLYMORPHISM 
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