supported by the internal grant of the Rıga Stradin‚s University(No.132311).
DNA methylation is one of the mechanisms of epigenetic control of gene expression,and a change in the intrinsic pattern can lead to various diseases and disorders.At the same time,this makes DNA methylation a disease-...
This article discusses the coexistence of prostate adenocarcinoma and prostate urothelial carcinoma.Combining existing literature and research results,the potential mechanisms of the co-occurrence of these two cancers...
supported by the NationalNature Science Foundation of China(No.82270810).
Benign prostatic hyperplasia(BPH)is one of the most frequently diagnosed benign disorders that cause dysuria in middle-aged and elderlymen.Some patientswith BPH have relatively small prostates(referred to as small-vol...
supported by a grant from the Basic and Applied Basic Research Foundation of Guangdong Province,China(grant no.2019A1515010386).
Background:Bipolar transurethral enucleation of the prostate(B-TUEP)is a well-established surgical treatment for benign prostatic hyperplasia(BPH);however,its efficacy may vary depending on patient characteristics.Mag...
Prostate cancer (PCa) is the second most common type of cancer among men worldwide and one of the leading causes of cancer-related deaths. According to data from the World Health Organization (WHO), this cancer causes...
supported by the National Natural Science Foundation of China,China (No.62101319,82170788);the Medical Discipline Construction Project of the Health System of Pudong New Area (China) (No.PYWgf2021-06).
Cell typing is an important step in the single-cell RNA sequencing(scRNA-seq)analysis.Although some cell marker databases and cell typing tools have been proposed,limited roles are in prostate cell typing.Through lite...
This opinion focuses on the management of low-and intermediate-risk prostate cancer(PCa)groups,emphasizing the need for additional prognostic factors beyond existing risk categories.Molecular biology and multiparametr...
supported by the National Key Research and Development Program of China(2021YFC2009300 and 2021YFC2009305 to Xu D);Science and Technology Commission of Shanghai Municipality(20Y11904700 to Xu D);National Nature Science Foundation of China(82173045 and 81972405 to Xu D,82072844 and 82272878 to Chen L,82003136 and 82272854 to Huang H);Nature Science Foundation of Shanghai(20ZR1433600,to Chen L);the Shanghai Sailing Program(22YF1440500 to Huang D);the Science and Technology Innovation Action Plan of Shanghai(1Y11904500 to Huang H).
Objective:This study aimed to figure out whether the combination of the prostate health index(PHI)and prostate-specific membrane antigen(PSMA)-PET/MR could improve the diagnostic accuracy for prostate cancer(PCa)than ...
Prostate cancer risk stratification relies on several clinical factors. Low-risk patients, characterized by T1–T2a stage, Gleason score (GS) ≤6, and prostate-specific antigen (PSA) <10 ng ml−1, exhibit an excellent ...