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作品数:798被引量:1736H指数:18
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相关作者:魏强董柏君曾浩吴开杰贺大林更多>>
相关机构:北京大学第一医院四川大学华西医院浙江大学医学院附属第一医院首都医科大学更多>>
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相关基金:国家自然科学基金国家重点基础研究发展计划广东省自然科学基金中国博士后科学基金更多>>
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Allele-specific methylation of the PSA promoter in prostate cells:A new translational marker for the differential diagnosis of prostate cancer
《Genes & Diseases》2025年第3期61-63,共3页Mikhail Baryshev Irina Maksimova Ilona Sasoveca 
supported by the internal grant of the Rıga Stradin‚s University(No.132311).
DNA methylation is one of the mechanisms of epigenetic control of gene expression,and a change in the intrinsic pattern can lead to various diseases and disorders.At the same time,this makes DNA methylation a disease-...
关键词:dna methylation prostate adenocarcinoma prostate cancer pca tumor marker allele specific methylation epigenetic control gene expressionand prostate cells psa promoter 
Concurrent occurrence of adenocarcinoma and urothelial carcinoma of the prostate:Coexistence mechanisms from multiple perspectives
《World Journal of Clinical Cases》2025年第12期5-9,共5页Xu-Chang Liu Yu-Xiang Liu Chun Liu 
This article discusses the coexistence of prostate adenocarcinoma and prostate urothelial carcinoma.Combining existing literature and research results,the potential mechanisms of the co-occurrence of these two cancers...
关键词:Prostate adenocarcinoma Prostate urothelial carcinoma Coexistence mechanism Transformation mechanism TUMOR 
Beyond size:A comprehensive overview of small-volume benign prostatic hyperplasia
《Current Urology》2025年第1期1-5,共5页Junhao Xu Bangmin Han Shujie Xia Yifeng Jing 
supported by the NationalNature Science Foundation of China(No.82270810).
Benign prostatic hyperplasia(BPH)is one of the most frequently diagnosed benign disorders that cause dysuria in middle-aged and elderlymen.Some patientswith BPH have relatively small prostates(referred to as small-vol...
关键词:Small-volume prostate Benign prostatic hyperplasia Surgical treatment Bladder neck contracture 
Clinical-radiomics combination model for predicting the short-term efficacy of bipolar transurethral enucleation of the prostate in patients with benign prostatic hyperplasia
《Current Urology》2025年第1期30-38,共9页Tianyou Zhang Zijun Mo Jiayu Huang Jun Wang Yiran Tao Lei Ye Wenwen Zhong Bing Yao Hu Qu Bo Ma Dejuan Wang Jiahui Mo Chunwei Ye Junying Zhu Jianguang Qiu 
supported by a grant from the Basic and Applied Basic Research Foundation of Guangdong Province,China(grant no.2019A1515010386).
Background:Bipolar transurethral enucleation of the prostate(B-TUEP)is a well-established surgical treatment for benign prostatic hyperplasia(BPH);however,its efficacy may vary depending on patient characteristics.Mag...
关键词:Benign prostatic hyperplasia Radiomics Prediction model Surgical efficacy Transurethral enucleation of the prostate 
Overview of the Impact of PSMA PET on the Management of Prostate Cancer Patients
《Journal of Biosciences and Medicines》2025年第2期169-189,共21页Jinyu Zhang Xin Dai Xinyi Ren Yuxin Zheng Jia Liu Gang Cheng 
Prostate cancer (PCa) is the second most common type of cancer among men worldwide and one of the leading causes of cancer-related deaths. According to data from the World Health Organization (WHO), this cancer causes...
关键词:PSMA PET Prostate Cancer Molecular Imaging Radioligand Therapy 
Patient-reported outcomes of rezvilutamide versus bicalutamide in combination with androgen deprivation therapy in high-volume metastatic hormone-sensitive prostate cancer patients (CHART): a randomized, phase 3 study
《Signal Transduction and Targeted Therapy》2025年第1期360-368,共9页Hongkai Wang Shusuan Jiang Hong Luo Fangjian Zhou Dalin He Lulin Ma Hongqian Guo Chaozhao Liang Tie Chong Jun Jiang Zhiwen Chen Yong Wang Qing Zou Ye Tian Jun Xiao Jian Huang Jinchao Chen Qiang Dong Xiaoping Zhang Hanzhong Li Xinfeng Yang Jianpo Lian Wenliang Wang Dingwei Ye 
The randomized phase 3 CHART trial(NCT03520478)revealed that rezvilutamide(REZ)plus androgen deprivation therapy(ADT)in high-volume,metastatic,hormone-sensitive prostate cancer(mHSPC)significantly enhanced radiographi...
关键词:patients cancer RANDOMIZED 
Performance analysis of markers for prostate cell typing in single-cell data
《Genes & Diseases》2024年第6期52-55,共4页Yanting Shen Xiawei Fei Junyan Xu Rui Yang Qinyu Ge Zhong Wang 
supported by the National Natural Science Foundation of China,China (No.62101319,82170788);the Medical Discipline Construction Project of the Health System of Pudong New Area (China) (No.PYWgf2021-06).
Cell typing is an important step in the single-cell RNA sequencing(scRNA-seq)analysis.Although some cell marker databases and cell typing tools have been proposed,limited roles are in prostate cell typing.Through lite...
关键词:ANALYSIS ANALYSIS TYPING 
Prostate cancer biology from clinical prognostic low-to intermediate-risk groups:looking up at the multiple patterns tracking the way forward被引量:1
《Asian Journal of Andrology》2024年第6期557-558,共2页Antonio Benito Porcaro 
This opinion focuses on the management of low-and intermediate-risk prostate cancer(PCa)groups,emphasizing the need for additional prognostic factors beyond existing risk categories.Molecular biology and multiparametr...
关键词:INVASION ENDOGENOUS LOOKING 
Diagnostic value comparison of the combination of prostate-specific membrane antigen-body PET/MR and the prostate health index with each alone in early diagnosis of prostate cancer
《Asian Journal of Urology》2024年第4期555-562,共8页Jiacheng Liu Xiaoyi Lin Da Huang Miao Zhang Ao Liu Xiaohao Ruan Jingrong Jiang Hai Huang Lu Chen Danfeng Xu 
supported by the National Key Research and Development Program of China(2021YFC2009300 and 2021YFC2009305 to Xu D);Science and Technology Commission of Shanghai Municipality(20Y11904700 to Xu D);National Nature Science Foundation of China(82173045 and 81972405 to Xu D,82072844 and 82272878 to Chen L,82003136 and 82272854 to Huang H);Nature Science Foundation of Shanghai(20ZR1433600,to Chen L);the Shanghai Sailing Program(22YF1440500 to Huang D);the Science and Technology Innovation Action Plan of Shanghai(1Y11904500 to Huang H).
Objective:This study aimed to figure out whether the combination of the prostate health index(PHI)and prostate-specific membrane antigen(PSMA)-PET/MR could improve the diagnostic accuracy for prostate cancer(PCa)than ...
关键词:Prostate cancer Prostate-specific membrane antigen Prostate health index Prostate biopsy Diagnosis 
PSA as the driving biomarker to manage low-and intermediate-risk prostate cancer patients in clinical practice被引量:1
《Asian Journal of Andrology》2024年第6期567-568,共2页Enrico Ricevuto Celeste Morgani Fabrizia Seri Gemma Bruera 
Prostate cancer risk stratification relies on several clinical factors. Low-risk patients, characterized by T1–T2a stage, Gleason score (GS) ≤6, and prostate-specific antigen (PSA) <10 ng ml−1, exhibit an excellent ...
关键词:patients CLINICAL cancer 
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