Prostate cancer biology from clinical prognostic low-to intermediate-risk groups:looking up at the multiple patterns tracking the way forward  

作　　者：Antonio Benito Porcaro 

机构地区：[1]Department of Urology,University of Verona,Azienda Ospedaliera Universitaria Integrata,Verona 37124,Italy

出　　处：《Asian Journal of Andrology》2024年第6期557-558,共2页亚洲男性学杂志（英文版）

摘　　要：This opinion focuses on the management of low-and intermediate-risk prostate cancer(PCa)groups,emphasizing the need for additional prognostic factors beyond existing risk categories.Molecular biology and multiparametric magnetic resonance imaging(mpMRI)applications are still facing challenges or limitations,whereas nomograms,particularly those predicting pelvic lymph node invasion and therefore associating with aggressive biology,could potentially have a prognostic impact on disease progression.We also discuss the impact of the prostate microenvironment,endocrine dependency,and variations in testosterone levels on cancer biology,introducing new concepts such as endogenous testosterone density.

关 键 词：INVASION ENDOGENOUS LOOKING 

分 类 号：R737.25[医药卫生—肿瘤]