CLINICAL

作品数:3195被引量:6249H指数:27
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相关领域:医药卫生更多>>
相关作者:吴泰相李幼平钟紫红李静张罗更多>>
相关机构:四川大学中国医学科学院北京协和医学院重庆医科大学首都医科大学更多>>
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相关基金:国家自然科学基金国家重点基础研究发展计划中国博士后科学基金上海市教育委员会重点学科基金更多>>
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Chemical exchange saturation transfer MRI for neurodegenerative diseases:An update on clinical and preclinical studies
《Neural Regeneration Research》2026年第2期553-568,共16页Ahelijiang Saiyisan Shihao Zeng Huabin Zhang Ziyan Wang Jiawen Wang Pei Cai Jianpan Huang 
supported by The University of Hong Kong,China(109000487,109001694,204610401,and 204610519);National Natural Science Foundation of China(82402225)(to JH).
Chemical exchange saturation transfer magnetic resonance imaging is an advanced imaging technique that enables the detection of compounds at low concentrations with high sensitivity and spatial resolution and has been...
关键词:Alzheimer’s disease chemical exchange saturation transfer Huntington’s disease magnetic resonance imaging molecular imaging multiple sclerosis neurodegenerative disease Parkinson’s disease 
The loaded matrix:neurotrophin-enriched hydrogels for stem cell brain repair in Parkinson's disease
《Neural Regeneration Research》2025年第8期2315-2316,共2页Giulia Comini Eilis Dowd 
funded by The Michael J.Fox Foundation for Parkinson’s Research(grant numbers:17244 and 023410);Science Foundation Ireland(grant number:19/FFP/6554)(to ED)。
More than 200 years after Parkinson's disease was first described by the English surgeon whose name would eventually be given to the condition,available treatments remain purely symptomatic,leaving a critical unmet cl...
关键词:CLINICAL loaded eventually 
Clinical bladder evaluation:A new,cost-effective,clinical method for neurogenic bladder evaluation and rehabilitation
《World Journal of Clinical Cases》2025年第20期1-5,共5页Raktim Swarnakar Shiv Lal Yadav 
Clinical bladder evaluation is a cost-effective,non-invasive method for diagnosing and managing urinary dysfunction,particularly in patients with neurogenic bladder or other impairments.This process aims to assess bla...
关键词:Clinical bladder evaluation Neurogenic bladder Post-void residual Upper motor neuron bladder Lower motor neuron bladder Bladder capacity INCONTINENCE Low-resource settings Urodynamics alternative 
Monogenic diabetes:An evidence-based clinical approach
《World Journal of Diabetes》2025年第5期47-70,共24页Saptarshi Bhattacharya Cornelius J Fernandez Abul Bashar Mohammad Kamrul-Hasan Joseph M Pappachan 
Monogenic diabetes is a heterogeneous disorder characterized by hyperglycemia arising from defects in a single gene.Maturity-onset diabetes of the young(MODY)is the most common type with 14 subtypes,each linked to spe...
关键词:Monogenic diabetes Maturity-onset diabetes of the young Neonatal diabetes Mitochondrial diabetes Insulin resistance syndrome Monogenic autoimmune diabetes Next-generation sequencing 
Stem cell therapy for intervertebral disc degeneration:Clinical progress with exosomes and gene vectors
《World Journal of Stem Cells》2025年第4期20-35,共16页Zhi-Peng Li Han Li Yu-Hua Ruan Peng Wang Meng-Ting Zhu Wei-Ping Fu Rui-Bo Wang Xiao-Dong Tang Qi Zhang Sen-Li Li He Yin Cheng-Jin Li Yi-Gong Tian Rui-Ning Han Yao-Bin Wang Chang-Jiang Zhang 
Supported by Henan Province Key Research and Development Program,No.231111311000;Henan Provincial Science and Technology Research Project,No.232102310411;Henan Province Medical Science and Technology Key Project,No.LHGJ20220566 and No.LHGJ20240365;Henan Province Medical Education Research Project,No.WJLX2023079;and Zhengzhou Medical and Health Technology Innovation Guidance Program,No.2024YLZDJH022.
Intervertebral disc degeneration is a leading cause of lower back pain and is characterized by pathological processes such as nucleus pulposus cell apoptosis,extracellular matrix imbalance,and annulus fibrosus rupture...
关键词:EXOSOMES Extracellular matrix repair Gene vector system Hypoxic environment Intervertebral disc degeneration Mesenchymal stem cells Regenerative medicine Stem cell therapy 
A rare case of thymic carcinoma metastasize to liver
《Hepatobiliary & Pancreatic Diseases International》2025年第2期217-220,共4页Yi-Fan Jiang Jian Wu Di-Yu Chen 
supported by a grant from the National Natural Science Foundation of China(No.82202974)。
To the Editor:Thymic carcinoma is a highly aggressive subtype of thymomas,accounting for 1%of thymic malignancies.It predominantly(80%)manifests in the anterosuperior mediastinum[1].Nevertheless,the occurrence of extr...
关键词:CLINICAL RARE SIZE 
Importance of early detection in multiple endocrine neoplasia type 1: Clinical insights and future directions
《World Journal of Gastrointestinal Oncology》2025年第4期1-7,共7页Mei-Jing Ren Zi-Li Zhang Can Tian Gui-Qiu Liu Chuan-Shan Zhang Hai-Bo Yu Qi Xin 
Tianjin Third Central Hospital,No.2019YNR3.
Multiple endocrine neoplasia type 1(MEN1)is an autosomal-inherited syndrome involving multiple endocrine tumors.It is characterized by multiple mutations in the tumor suppressor gene MEN1,which is located on chromosom...
关键词:Multiple endocrine neoplasia type 1 DIAGNOSIS Treatment Primary hyperparathyroidism Pancreatic neuroendocrine neoplasms 
Application of Ideological and Political Theories Teaching in Clinical Practice Course for Nursing Interns Based on Nightingale Spirit
《Medicinal Plant》2025年第2期84-87,共4页Songhong XIE Yingjia XU Ling LI Danna LIU 
Supported by 2024 Basic Research and Applied Basic Research Project in Neijiang City(2024 NJJCYJZZXR001)。
[Objectives]To explore the effectiveness of integrating ideological and political education based on the Nightingale spirit into the clinical practice curriculum for nursing interns.[Methods]A total of 90 questionnair...
关键词:Nightingale spirit Nursing intern Clinical practice Ideological and political theories teaching in the course Professional identity 
Aggregation-induced emission-based covalent-organic framework fluorescent probes for clinical detection of aluminum and daily prevention of Alzheimer's disease by naked-eye
《Science China Chemistry》2025年第4期1326-1336,共11页Yun Zhao Enpeng Xi Ziwei Wang Qi Ding Kangning Liu Jinxing Zhu Xuhan Wu Yiling Xie Fuming Yang Nan Gao Hanjun Sun Yajie Yang Ye Yuan Guangshan Zhu 
supported by the National Key R&D Program of China(2022YFB3805902);the National Natural Science Foundation of China(22131004,U21A20330,21975039 and 22077118);the“111”project(B18012);the Fundamental Research Funds for the Central Universities,Excellent Youth Team Program(2412023YQ001);the Finance Special Project on Medical and Health Talents of the Finance Department of Jilin Province(JLSWSRCZX2023-52);WBE Liver Fibrosis Foundation(2020009).
Alzheimer's disease(AD)is a neurodegenerative disease and a major threat to human health worldwide.The association between aluminum exposure and AD has been widely reported.Owing to the ubiquitous presence of aluminum...
关键词:Alzheimer's disease clinical detection daily prevention aluminum exposure aggregation-induced emission 
Asking one mechanism in glial cells during neuroinflammation
《Neural Regeneration Research》2025年第4期1077-1078,共2页Xiaoli Guo Chikako Harada Takayuki Harada 
supported by Japan Society for the Promotion of Science(JSPS)KAKENHI Grants-in-Aid for Scientific Research(JP21K09688 and JP24K12795 to XG;JP22K09804 to CH;JP19KK0229,JP21H02819,JP21K18279,and JP24H00583 to TH),Shiseido Female Researcher Science Grant(to XG)and the Takeda Science Foundation(to TH).
Multiple sclerosis(MS),which is characterized by inflammatory demyelination in the central nervous system(CNS),is the most common neurological disease in the young adult population.Experimental autoimmune encephalomye...
关键词:INFLAMMATION CLINICAL 
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