Supported by National Natural Science Foundation of China,No.874063.
BACKGROUND Keratin 80(KRT80),a type I intermediate filament protein,is a member of the keratin family with specialized functions in epithelial tissues.While KRT80 has been implicated in both normal physiological proce...
Beak deformation,known as avian keratin disorder(AKD),can impair feeding and preening of birds,reducing their survival.This disorder is apparently caused by Poecivirus infection,although to date,the viral origin has b...
Supported by the National Natural Science Foundation of China,No.82160113;the“Xingdian Talents”Support Project of Yunnan Province,No.RLMY20220007;the Yunnan Province Clinical Research Center for Digestive Diseases,No.202102AA100062;the Applied Basic Research Projects of Yunnan Province,No.2019FE001-039.
BACKGROUND External factors in ulcerative colitis(UC)exacerbate colonic epithelial permea-bility and inflammatory responses.Keratin 1(KRT1)is crucial in regulating these alterations,but its specific role in the progre...
supported by the National Natural Science Foundation of China(Grant Nos.42288201&41922011);the Strategic Priority Research Program of the Chinese Academy of Sciences(Grant No.XDB26000000);the Fundamental Research Funds for the Central Universities(Grant No.0206-14380219)。
Mammalian hair,as a key feature related to endothermy,physical protection,and camouflage,has a long geohistorical record that dates back even to the Mesozoic.However,the limited information on the taphonomy of hair hi...
Taking a widely contaminated yet abundant waste,such as poultry feathers,and extracting keratin from this struc-ture appears to be a real challenge whenever the preservation of the secondary structure of the protein i...
European Union's Horizon Europe research and innovation programme under grant agreement No.101060607;for the research and innovation programme under grant agreement No.101037796;National Recovery and Resilience Plan(NRRP),Mission 4.Component 2 Investment 1.3-Call for proposals No.341 of March 15,2022 of Italian Ministry of University and Research funded by the European Union-NextGenerationEU;Award Number:Project code PE00000003,Concession Decree No.1550 of October 11,2022 adopted by the Italian Ministry of University and Research,CUP H93C22000630001,Project title“ON Foods-Research and innovation network on food and nutrition Sustainability,Safety and Security-Working ON Foods”.
Keratins and corneous proteins are key components of biomaterials used in a wide range of applications and are potential substitutes for petrochemical-based products. Horns, hooves, feathers, claws, and similar animal...
supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences(No.XDA16040101);the National Key R&D Program of China(No.2021YFC2701603);the National Natural Science Foundation of China(No.82271653);the Jiangsu Provincial Obstetrics and Gynecology Innovation Center(No.CXZX202229).
The human vaginal epithelium is a crucial component of numerous reproductive processes and serves as a vital protective barrier against pathogenic invasion.Despite its significance,a comprehensive exploration of its m...
National Natural Science Foundation of China,Grant/Award Numbers:11972099,82202340;Venture&Innovation Support Program for Chongqing Overseas Returnees,Grant/Award Number:cx2020079;Scientific and Fundamental Research Funds for the Central Universities,Grant/Award Numbers:2023CDJXY-050,2023CDJXY-051。
Recombinant keratins possess strong hemostatic and wound healing properties but suffer from poor water solubility that restricts their bioactivities in biomedical applications.Herein,we report the rational design and ...
supported by the research project of Russian Science Foundation N 22-14-00227.
Dear Editor,The problem of age estimation in amphibians and reptiles with annual fluctuations of growth pattern has been considered to be mostly solved since the skeletochronological method was introduced(Kleinenberg ...
supported by the National Natural Science Fund of China(81873923);Jiangsu Higher Education Institutions(19KJA310001 and PAPD);Jiangsu Collaborative Innovation Center of Biomedical Functional Materials.
Nitric oxide(NO)and hydrogen sulfide(H_(2)S)gasotransmitters exhibit potential therapeutic effects in the car-diovascular system.Herein,biomimicking multilayer structures of biological blood vessels,bilayer smalldiame...