supported by the Science and Technology Council,Taiwan,China(NSTC 112-2320-B-039-057 and MOST 111-2320-B-039-067-MY3);the China Medical University,Taiwan,China(CMU112-S-18),awarded to Yuan-Soon Ho;the China Medical University,Taiwan,China(CMU112-N-02),awarded to Li-Ching Chen;the Science and Technology Council,Taiwan,China(MOST 110-2320B-039-079)。
This study presents novel findings on the potential of phloretin,an apple polyphenol,to enhance the effectiveness of anti-human epidermal growth factor receptor-2(HER2)antibody therapy in HER2-positive breast cancer p...
supported by the National Natural Science Foundation of China(U23A20242 and U22A20523);the Fundamental Research Funds for the Central Universities under Grant 2023JCXK-01。
Acinetobacter baumannii(A.baumannii)is well known for its virulence and persistence,particularly in intensive care units.Therefore,new strategies and candidates to treat A.baumannii infection are urgently needed consi...
supported by the National Natural Science Foundation(31972089);the 2020 Team Innovation Project from the Fundamental Scientific Research Special Capital Fund of the National Universities,China(GK202001008).
Although the catabolic pathway of some flavonoids in the human colon has been elucidated,knowledge of related gut microbes and responsible enzymes is still limited.In this study,a phloretin hydrolase gene(phy)from Fla...
Objective:To compare the cardioprotective efficacy of equimolar doses(50 mM/kg,p.o.)of phloretin and genistein against doxorubicin-induced cardiotoxicity in rats.Methods:Cardiotoxicity was induced in rats by intraperi...
financially supported by Talents Team Construction Fund of Northwestern Polytechnical University (NWPU);the National Natural Science Foundation of China (31701722);the China Postdoctoral Science Foundation (2017M620471);the National Natural Science Foundation of China (31901026)。
Phloretin is an important skin-lightening and depigmenting agent from the peel of apples. Although de novo production of phloretin has been realized in microbes using the natural pathway from plants, the efficiency of...
the European Commission(H2020-MSCA-IF-79212);the Ministry of Science,Innovation and Universities,Spain(Grants:RYC-2014-15581,AGL2016–81890-REDT,AGL2017–88329-R and FJCI-2017-31689);the Regional Government of Catalonia,Spain(2017-SGR-1229).
Background:Aquaporins(AQPs)are a family of transmembrane water channels that includes orthodox AQPs,aquaglyceroporins(GLPs)and super AQPs.AQP3,AQP7,AQP9 and AQP11 have been identified in boar sperm,and they are crucia...
Reactive oxygen species [ROS] cause oxidative damage to the tissues and protection from such damages is provided by endogenous and exogenous antioxidants. Much research work has been carried out in recent years on the...