the European Commission(H2020-MSCA-IF-79212);the Ministry of Science,Innovation and Universities,Spain(Grants:RYC-2014-15581,AGL2016–81890-REDT,AGL2017–88329-R and FJCI-2017-31689);the Regional Government of Catalonia,Spain(2017-SGR-1229).
Background:Aquaporins(AQPs)are a family of transmembrane water channels that includes orthodox AQPs,aquaglyceroporins(GLPs)and super AQPs.AQP3,AQP7,AQP9 and AQP11 have been identified in boar sperm,and they are crucia...
Acetazolamide(molecular mass(MM),222)belongs to the class of sulfonamides(R-SO2-NH2)and is one of the strongest pharmacological inhibitors of carbonic anhydrase activity.Acetazolamide is excreted unchanged in the urin...
A novel Acetazolamide condensed 1,4-dihydropyridines was set up by treating of N-(5-acetamido-1,3,4-thiadiazol-2-ylsulfonyl)-3-oxobutanamide with an aryl aldehyde and 25-30%alkali with sight amount of barium nitrate a...
Traumatic brain injuries are an important cause of morbidity and mortality around the world. These types of lesions are often associated with increased intracranial pressure and cerebral edema, proper management of th...
The intent of this study was to provide topical delivery of acetazolamide by preparing chitosan-STPP (sodium tripolyphosphate) nanoparticles of acetazolamide and evaluate the particle size, zeta potential, drug entrap...
The development of the extemporaneous preparations allows physicians to adjust the dose for pediatric patients and provides for a more convenient dosage vehicle for those patients with difficulty swallowing tablets[1]...
Background:Heliotropium indicum is used as a traditional remedy for hypertension in Ghana.The aim of the study was to evaluate the anti-glaucoma potential of an aqueous whole plant extract of H.indicum to manage exper...
Background: Spontaneous CSF leak represents less frequent cause of CSF leak, but cases are more difficult to control, with the highest failure rate and recurrence despite adequate repair. The problems in these cases m...
Objective To explore the CT perfusion imaging with acetazolamide(ACZ)challenge test in the diagnosis of chronic cerebral insufficiency.Methods 100 patients undergoing health examination in our hospital from Aug2009 to...
partly supported by the Molecular Imaging Program, a grant(21591561) from the Ministry of Education,Culture,Sports, Science,and Technology and the Japan Science and Technology Agency,Japan;the Research Promotion Program on Health from the National Institute of Biomedical Innovation,Japan;a Grant-in-Aid(H21-019 and H21-5) from the Ministry of Health, Welfare,and Labour,Japan
Paradoxical reduction of cerebral blood flow (CBF) after administration of the vasodilator acetazolamide is the most severe stage of cerebrovascular reactivity failure and is often associated with an increased oxyge...