ACETYLCHOLINESTERASE

作品数:173被引量:360H指数:9
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相关领域:医药卫生更多>>
相关作者:孙曼霁李飞韩召军薛丽周正堂更多>>
相关机构:军事医学科学院中国农业大学中国科学院上海生命科学研究院华中师范大学更多>>
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相关基金:国家自然科学基金国家重点基础研究发展计划广西壮族自治区自然科学基金山西省自然科学基金更多>>
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Antiparasitic Activity and Potential Active Compounds from Azadirachta Indica Revealed by Affinity Ultrafiltration Chromatography–Mass Spectrometry with Acetylcholinesterase and Lactate Dehydrogenases
《Journal of Analysis and Testing》2024年第4期403-414,共12页Minxia Fan Tojofaniry Fabien Rakotondrabe Guilin Chen Mingquan Guo 
the financial support from the Natural Science Foundation of Hubei Province(2021CFB263);the Opening Project of Hubei Key Laboratory of Purification and Application of Plant Anti-cancer Active Ingredients(HLPAI2023003)。
Azadirachta indica(A.indica)has traditionally been used to treat parasitic diseases,while its antiparasitic compounds and their mechanism remain ambiguous.Acetylcholinesterase(AChE)and lactate dehydrogenases(LDH)are t...
关键词:Azadirachta indica Parasitic diseases UF-LC-MS Molecular docking 
Target-site mediated insecticide resistance in major mosquito(Diptera:Culicidae)vectors:A systematic review
《Asian Pacific Journal of Tropical Medicine》2024年第11期481-490,I0001-I0028,共38页Subhajit Das Abhirup Saha Prapti Das Debayan Raha Dhiraj Saha 
The use of insecticides remain the most effective vector control approach for mosquito borne diseases like malaria,dengue fever,chikungunya,and Zika virus disease;however,their increasing resistance has complicated th...
关键词:MOSQUITO CULEX ANOPHELES AEDES Insecticide resistance kdr ACETYLCHOLINESTERASE GABAA receptor 
Deep learning-based drug screening for the discovery of potential therapeutic agents for Alzheimer's disease
《Journal of Pharmaceutical Analysis》2024年第10期1514-1526,共13页Tong Wu Ruimei Lin Pengdi Cui Jie Yong Heshui Yu Zheng Li 
This work was supported by the Science and Technology Project of Haihe Laboratory of Modern Chinese Medicine,China(Grant No.:22HHZYSS00003);the Science and Technology Program of Tianjin,China(Grant No.:22ZYJDSS00100);The authors would like to thank the support from Innovation Team and Talents Cultivation Program of National Administration of Traditional Chinese Medicine,China(Grant No:ZYYCXTD-D-202002).
Alzheimer's disease(AD)is gradually increasing in prevalence and the complexity of its pathogenesis has led to a lengthy process of developing therapeutic drugs with limited success.Faced with this challenge,we propos...
关键词:Alzheimer's disease Deep learning models Drug screening Kaixinsan formula ACETYLCHOLINESTERASE Monoamine oxidase-A 
Neurotoxicity of tetramethylammonium ion on larval and juvenile zebrafish:Effects on neurobehaviors and multiple biomarkers
《Journal of Environmental Sciences》2024年第9期138-147,共10页Ruixin Zhang Rui Wang Jiajun Chang GDaniel Sheng Daqiang Yin 
supported by the National Key Research and Development Program of China(No.2019YFC0408203)。
Tetramethylammonium hydroxide(TMAH)is an important compound that utilized and released by the rapidly expanding semiconductor industry,which could hardly be removed by the conventional wastewater treatment techniques....
关键词:TETRAMETHYLAMMONIUM ZEBRAFISH Oxidative stress ACETYLCHOLINESTERASE NEUROBEHAVIOR 
High-precision colorimetric-fluorescent dual-mode biosensor for detecting acetylcholinesterase based on a trimetallic nanozyme for efficient peroxidase-mimicking
《Journal of Materials Science & Technology》2024年第24期168-180,共13页Meie Zheng Mingxing Liu Zichen Song Fei Ma Hongda Zhu Huiling Guo Hongmei Sun 
supported by the Hubei University of Technology Graduate Research Innovation Project(No.2022048);the Natural Science Foundation Project of Hubei Province(grant No.2022CFB533);the Scientific Research Plan of Education Department of Hubei Province(grant No.D20222702);the Natural Science Project of Xiaogan city(grant No.XGKJ20210100014).
Highly sensitive and stable acetylcholinesterase detection is critical for diagnosing and treating various neurotransmission-related diseases.In this study,a novel colorimetric-fluorescent dual-mode biosensor based on...
关键词:Graphitic carbon nitride Zeolitic imidazolate framework-8 Colorimetric-fluorescent dual-mode sensor Density functional theory calculations ACETYLCHOLINESTERASE 
Cholinesterase Activity as an Indicator of Health Risks among Kou Valley Farmers
《Journal of Biosciences and Medicines》2024年第7期71-86,共16页Thiombiano Cherileila Hien S. Aristide Koevi Nadège Bayili Bazoma Ouattara Abdoulaye Traore Patrice Traore T. Isidore Hien Herve 
Introduction: Pesticides are currently an essential component of agricultural production techniques for controlling pests and weeds. In Burkina Faso, non-compliance with good practice in the use of pesticides poses a ...
关键词:PESTICIDES ENVIRONMENTAL Sanitary Risk ACETYLCHOLINESTERASE FARMERS Bama Burkina Faso 
Phytochemical analysis,antioxidant,acetylcholinesterase,andα-amylase inhibitors from Hippeastrum hybridum extract
《Journal of Traditional Chinese Medicine》2024年第3期496-504,共9页Naila Sher Mushtaq Ahmed Nadia Mushtaq 
the Higher Education Commission of Pakistan(HECPAK)(No:20-5082/NRPU/R&D/HEC)。
OBJECTIVE:To investigate the effects of Hippeastrum hybridum(HH)as a free radical scavenger,and an inhibitor of the two enzymes i-e Alpha-amylase(α-amylase)and acetylcholinesterase(AChE).METHODS:In this study,HH plan...
关键词:Hippeastrum hybridum PHYTOCHEMICALS ANTIOXIDANT ALPHA-AMYLASE ACETYLCHOLINESTERASE 
Emerging significance of butyrylcholinesterase被引量:1
《World Journal of Experimental Medicine》2024年第1期33-43,共11页Gumpeny R Sridhar Lakshmi Gumpeny 
Butyrylcholinesterase(BChE;EC 3.1.1.8),an enzyme structurally related to acetylcholinesterase,is widely distributed in the human body.It plays a role in the detoxification of chemicals such as succinylcholine,a muscle...
关键词:ESTERASE ACETYLCHOLINESTERASE Variant CHOLINERGIC Metabolic syndrome Cognition Knockout model 
New Neuraminidase Inhibitory Alkaloids from the Mangrove Soil-Derived Fungus Arthrinium sp.SCSIO 41305
《Journal of Ocean University of China》2023年第5期1446-1451,共6页HU Yiwei ZHAO Kai ZHU Junheng QI Xin CHEN Weihao SONG Yingying PANG Xiaoyan LIU Yonghong WANG Junfeng 
the Guangdong Basic and Applied Basic Research Foundation(Nos.2021 A1515011523,2021B1515120046);the Guangdong MEPP Funds(No.GDNRC[2021]48);the Finance Science and Technology Project of Hainan Province(No.ZDKJ202018);National Natural Science Foundation of China(No.41776169)。
New alkaloid,(E)-2-(hydroxyimino)-4-methylpentanamide(1)and a new cyclopentano[b]pyridine,4-hydroxy-7-methyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-one(2),together with ten known compounds(3–12)were isolated from the ...
关键词:Arthrinium ALKALOID pyridine NEURAMINIDASE ACETYLCHOLINESTERASE 
Aptamer-induced in-situ growth of acetylcholinesterase-Cu_(3)(PO_(4))_(2)hybrid nanoflowers for electrochemical detection of organophosphorus inhibitors
《Nano Research》2023年第10期12134-12143,共10页Limin Yang Linjiao Qu Xiaolong Zhang Mingming Li Zhen Liu 
the National Natural Science Foundation of China(No.31871878).
Enzyme-inorganic hybrid nanoflowers(HNFs)have shown excellent sensing capabilities due to their large specific surface area as well as the simplicity and mildness of the preparation process.However,coupling HNFs to el...
关键词:in-situ fabrication APTAMER enzyme-inorganic hybrid nanoflowers electrochemical biosensor acetylcholinesterase inhibitors 
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