ESTERASE

作品数：96被引量：141H指数：6
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Exploring Ester Prodrugs: A Comprehensive Review of Approaches, Applications, and Methods
《Pharmacology & Pharmacy》2024年第8期269-284,共16页Guangyang Zhou 
The review provides an overview of the approaches, applications, and methods for ester prodrugs. Ester prodrugs are pharmacologically inactive compounds in their original form but become active drugs on biotransformat...
关键词：Ester Prodrugs Solubility BIOAVAILABILITY Stability Ester Prodrug Approaches Simple Ester Prodrugs Amino Acid Ester Prodrugs Sugar Ester Prodrugs Lipid Ester Prodrugs Polymeric Ester Prodrugs Esterase-Responsive Nanoparticles Hydrolysis Cancer Treatment Cardiovascular Diseases Neurological Disorders 
Resistance risk assessment of six pyrethroids and acephate toward the resistant adult tarnished plant bug,Lygus lineolaris
《Insect Science》2024年第3期792-802,共11页Yuzhe Du Shane Scheibener Yucheng Zhu Maribel Portilla Mingling Zhang 
Due to rapidly developed resistance,pest management relies less on pyrethroids to control economically damaging infestations of the tarnished plant bug(TPB),Lygus lineolaris(Palisot de Beauvois)in cotton fields of Mis...
关键词：cytochrome P450-monooxygenases(P450) detoxification enzyme activities ESTERASE Lygus lineolaris pyrethroids and organophosphate resistance tarnished plant bug 
Biochemical Insights into Siderophore Esterases
《Journal of Biosciences and Medicines》2024年第2期60-69,共10页Dongyue Yan Yidao Jiang 
Iron is an essential but excessively toxic nutrient. Although iron is rich in nature, the acquisition of iron is a challenge to life. Its solubility is very low because it is mostly in the form of oxidation or hydroxi...
关键词：SIDEROPHORE Siderophore Esterase HYDROLYSIS ENTEROBACTIN Antibiotic 
Characterization of a Novel Esterase Belonging to Family V from Marinobacter flavimaris
《Journal of Ocean University of China》2024年第1期221-232,共12页HE Jingjing ZHANG Yunhui WU Leilei WANG Yaru ZHANG He LIU Zhengang SHI Xiaochong 
supported by the projects from the National Natural Science Foundation of China(No.42230411);the China Ocean Mineral Resources R and D Association(COMRA)Special Foundation(No.DY135-B2-10).
Lipolytic enzymes have attracted enormous attentions because of their ability in ester hydrolysis,ester synthesis,transesterification and other biochemical reactions.Bacteria are important sources of lipolytic enzymes...
关键词：ESTERASE Marinobacter flavimaris enzymatic properties lipolytic enzyme family V 
Discovery,characterization and mechanism of a Microbacterium esterase for key d-biotin chiral intermediate synthesis
《Bioresources and Bioprocessing》2024年第1期796-808,共13页Xinjia Li Haoran Yu Shengli Liu Baodi Ma Xiaomei Wu Xuesong Zheng Yi Xu 
supported by the Shanghai Committee of Science and Technology(No.13430503400);Project of Leading Talents in Shandong Taishan Industry(Grant No.LJNY202019);the Scientific Research Foundation for the Returned Overseas Chinese Scholars,State Education Ministry(No.ZX2012-05);Innovation Program of Shanghai Municipal Education Commission(No.11YZ227).
Esterases are crucial biocatalysts in chiral compound synthesis.Herein,a novel esterase EstSIT01 belonging to family V was identified from Microbacterium chocolatum SIT101 through genome mining and phylogenetic analys...
关键词：Genome mining ESTERASE Stereoselective hydrolysis D-BIOTIN 
Emerging significance of butyrylcholinesterase被引量：1
《World Journal of Experimental Medicine》2024年第1期33-43,共11页Gumpeny R Sridhar Lakshmi Gumpeny 
Butyrylcholinesterase(BChE;EC 3.1.1.8),an enzyme structurally related to acetylcholinesterase,is widely distributed in the human body.It plays a role in the detoxification of chemicals such as succinylcholine,a muscle...
关键词：ESTERASE ACETYLCHOLINESTERASE Variant CHOLINERGIC Metabolic syndrome Cognition Knockout model 
Crystal structure of the GDSL family esterase EstL5 in complex with PMSF reveals a branch channel of the active site pocket
《Acta Biochimica et Biophysica Sinica》2023年第11期1833-1839,共7页Runsha Chen Xuechun Gao Ting Nie Jinhong Wu Lin Wang Ali Osman Yan Feng Xianghong Li Yong Zhang 
supported by the grants from the National Key Research and Development Program of China (No.2020YFA0907702);the National Natural Science Foundation of China (Nos.32261143736 and 31770846);the Key Research and Development Project of Hunan Province (No.2022NK2032).
Esterases/lipases from the GDSL family have potential applications in the hydrolysis and synthesis of important esters of pharmaceutical,food,and biotechnical interests.However,the structural and functional understand...
关键词：GSDL esterase PMSF cavity CHANNEL crystal structure 
Alternative splicing of a carboxyl/choline esterase gene enhances the fenpropathrin tolerance of Tetranychus cinnabarinus
《Insect Science》2023年第5期1255-1266,共12页Peng Wei Xinying Zeng Haonan Han Yiqing Yang Youjun Zhang Lin He 
supported in part by the National Nature Sciences Foundation(32001935 and 31972297);the Fundamental Research Funds for the Central Universities(SWU-KR22005).
Detoxification plays a crucial role in agricultural pests to withstand pesticides,and cytochrome P450s,carboxyl/choline esterases(CCEs),and glutathione-S-transferases are the main proteins responsible for their detoxi...
关键词：alternative splicing carboxyl/choline esterase(CCE) detoxification function PYRETHROID pests 
P_(luxI)mutants with different promoting period and their application for quorum sensing regulated protein expression被引量：1
《Food Science and Human Wellness》2023年第5期1841-1849,共9页Zhuoning Cao Zhen Liu Guilin Zhang Xiangzhao Mao 
supported by the National Natural Science Foundation of China(31922072);Natural Science Foundation of Shandong Province(ZR2020JQ15);Project of Shandong Province Higher Educational Science and Technology Program(2019KJF012);Taishan Scholar Project of Shandong Province(tsqn201812020);China Agriculture Research System(CARS-48);Qingdao Science and Technology Demonstration and Guidance Project for Benefiting the People(20-3-4-28-nsh)。
Quorum sensing(QS)system can dynamically control the expression of proteins along with the cell growth.The promoting period of QS system has been little focused on until now.In this study,a self-induced dynamic regula...
关键词：Quorum sensing Promoter engineering ENZYMES Alginate lyase ESTERASE High-density fermentation 
Statins markedly potentiate aminopeptidase inhibitor activity against(drug-resistant)human acute myeloid leukemia cells
《Cancer Drug Resistance》2023年第3期430-446,共17页Gerrit Jansen Marjon Al Yehuda G.Assaraf Sarah Kammerer Johan van Meerloo Gert J.Ossenkoppele Jacqueline Cloos Godefridus J.Peters 
This study was supported by Cancer Center Amsterdam grants 07/36 and 2012-1-08.
Aim: This study aimed to decipher the molecular mechanism underlying the synergistic effect of inhibitors of the mevalonate-cholesterol pathway (i.e., statins) and aminopeptidase inhibitors (APis) on APi-sensitive and...
关键词：AMINOPEPTIDASE STATINS mevalonate pathway carboxyl esterase RHEB mTOR 
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