INSUFFICIENCY

作品数：178被引量：425H指数：11
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A canine model of reversible urethral sphincter insufficiency
《Animal Models and Experimental Medicine》2025年第2期372-377,共6页Pourya Shokri Shahin Tabatabaei Seyed Amir Mohsen Ziaee Mir Sepehr Pedram Mohammad Mehdi Dehghan Nasser Shakhssalim 
This study developed an animal model with internal and external urethral sphincter insufficiency by bypassing the sphincter without major damage so that the animal under study can return to normal life after the study...
关键词：animal model external urethral sphincter internal urethral sphincter urinary incontinence 
Dynamic plain abdominal film provides simple and effective diagnosis of delayed shunt insufficiency caused by abdominal adhesions after VP shunt
《Chinese Neurosurgical Journal》2024年第4期256-265,共10页Zhiqiang Liu Jintao Chen Chaoqun Weng Bei Liu Zhixiong Lin 
Background Many complications may occur after placement of the ventriculoperitoneal shunt (VP shunt) for hydrocephalus, and delayed shunt insufficiency (DSI) is among the most common. It is often caused by abdominal a...
关键词：HYDROCEPHALUS VP shunt DELAYED Shunt insufficiency 
Sepsis-associated liver injury:Mechanisms and potential therapeutic targets
《World Journal of Gastroenterology》2024年第42期4518-4522,共5页Jia-Wen Chen Chen-Yi Liu Shu Li Shi-Wen Wu Chao Cai Ming-Qin Lu 
The Zhejiang Medical and Health Science and Technology Program,China,No.2021KY205 and No.2024KY139;The Wenzhou Science and Technology Plan Project,China,No.Y2023111.
In this editorial,we examined a recent article in the World Journal of Gastroenterology that focused on sepsis-associated liver injury(SLI)and its treatment.SLI is a serious complication of sepsis,primarily caused by ...
关键词：Sepsis Sepsis-associated liver injury Gut-liver axis Immunosuppression Inflammation Immune dysregulation Glucocorticoid Adrenal cortical insufficiency 
Surgical and non-surgical risk factors affecting the insufficiency of ileocolic anastomosis after first-time surgery in Crohn’s disease patients
《World Journal of Gastrointestinal Surgery》2024年第10期3253-3260,共8页Jaroslaw Cwaliński Filip Lorek Łukasz Mazurkiewicz MichałMazurkiewicz Wojciech Lizurej Jacek Paszkowski Hanna Cholerzyńska Wiktoria Zasada 
BACKGROUND Crohn's disease(CD)often necessitates surgical intervention,particularly when it manifests in the terminal ileum and ileocecal valve.Despite undergoing radical surgery,a subset of patients experiences recur...
关键词：Crohn’s disease Ileocolic resection Anastomotic insufficiency Endoscopic surveillance SURGERY Risk factors 
Dominant negative effect as a novel mechanism of SPAST gene mutation in a large family with hereditary spastic paraplegia
《Genes & Diseases》2024年第5期74-77,共4页Ke Deng Haibo Ruan Feifei Yu Zhenle Pei Congjian Xu Shuo Zhang 
the Shanghai Science and Technology Innovation Action Plan Program of China(No.20Y11907200,22Y11907200);the National Natural Science Foundation of China(No.82201807);the Municipal Human Resources Development Program for Outstanding Young Talents in Medical and Health Sciences in Shanghai,China(No.2022YQ075);Shanghai“Rising Stars of Medical Talents”Youth Development Program(China).
Hereditary spastic paraplegia(HSP)is a group of disorders with genetic heterogeneity,lower-extremity weakness,and spasticity are the most common signs and symptoms.SPAST is the most frequently disease-causing gene.Spa...
关键词：BLADDER INSUFFICIENCY CLINICAL 
FLNB haploinsufficiency-related short stature:a new syndrome or an expanded spectrum of Larsen syndrome
《World Journal of Pediatrics》2024年第9期976-980,共5页Qing Wang Hong-Ying Wang Shui-Yan Wu Xue-Qian Wang Hai-Ying Wu Rong-Rong Xie Feng-Yun Wang Xiu-Li Chen Lin-Qi Chen Hai-Tao Lv Ting Chen 
supported by the Suzhou Personnel Planning Project(GSWS2020046);the Suzhou Science and Technology Development Project(SKY2023007);the Research Project of Jiangsu Commission of Health(M2021082);the Summit Project of Clinical Medicine(ML13100523)awarded to Ting Chen;It’s also supported by the Jiangsu Provincial Maternal and Child Health Care Program(F202119)awarded to Hong-Ying Wang;the Suzhou Clinical enter for Rare Disease(Szlcyxzxj202105).
FLNB encodes the protein filamin B(FLNB),which is expressed in chondrocytes of the human growth plate[1].To date,pathogenic mutations in the FLNB gene have solely been found to cause skeletal deformities,indicating th...
关键词：INSUFFICIENCY SKELETAL expanded 
A novel heterozygous SF1/NR5A1 gene variant causes 46,XY DSD-gonadal dysgenesis with hypergonadotropic hypogonadism without adrenal insufficiency被引量：1
《Genes & Diseases》2024年第4期128-130,共3页Luis Ramos 
the Declaration of Helsinki and the standard investigation protocols of the Institutional Ethical Committee for Investigation in Humans of the INCMNSZ(No.BRE-2614-18-21-1).
Steroidogenic factor 1(SF1/NR5A1;nuclear receptor subfamily 5 group A member 1)is an essential orphan protein involved in gonadal embryogenesis,sex determination,and reproductive endocrinology.
关键词：INSUFFICIENCY determination gonadal 
Impacts of pancreatic exocrine insufficiency on gut microbiota
《Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)》2024年第4期271-279,共9页Yulin GUO Feng CAO Fei LI 
supported by the Construction Project of Clinical Advanced Subjects of Capital Medical University(No.1192070312);the Beijing Municipal Science&Technology Commission(Nos.Z171100001017077 and Z191100006619038);the Capital Health Research and Development of Special(No.2020-1-2012);the Capital Medical University Youth Science Foundation(No.PTZ21035),China。
Pancreatic exocrine insufficiency(PEI)can be induced by various kinds of diseases,including chronic pancreatitis,acute pancreatitis,and post-pancreatectomy.The main pathogenetic mechanism of PEI involves the decline o...
关键词：Pancreatic exocrine insufficiency Gut microbiota Gut microbiome Pancreatic enzyme replacement therapy 
Rare variants in FANCJ induce premature ovarian insufficiency in humans and mice
《Journal of Genetics and Genomics》2024年第2期252-255,共4页Xi Yang Shuting Ren Jialin Yang Yuncheng Pan Zixue Zhou Qing Chen Yunzheng Fang Lingyue Shang Feng Zhang Xiaojin Zhang Yanhua Wu 
supported by the National Natural Science Foundation of China(32270658 and 32288101);the National Key Research and Development Program of China(2022YFC2703800);the Natural Science Foundation of Shanghai(20ZR1407000).
Premature ovarian insufficiency(POI)is a severe female reproductive disorder that affects 1%of women in general populations(European Society for Human Reproduction and Embryology[ESHRE]Guideline Group on POI et al.,20...
关键词：INSUFFICIENCY FERTILITY 
Influence of Prenatal Surveillance on Maternal and Perinatal Prognosis: A Prospective Study over 6 Months at the Maternity Ward of the Owendo University Hospital (Gabon)
《Open Journal of Obstetrics and Gynecology》2024年第2期301-311,共11页Boniface Sima Ole Sidy Gérard Mba Edou Ulysse Minkobam Désire Assoume Ophélie Makoyo Komba Nathalie Ambounda Pamphile Assoumou Jacques Albert Bang Ntamack Sosthène Mayi Tsonga Jean François Meye 
Introduction: The occurrence of pregnancy in women is a risky situation. Prenatal care is necessary, which is not often the case in our context. Aim: To analyze the influence of antenatal surveillance on maternal and ...
关键词：ANC INSUFFICIENCY Maternal Pathologies Perinatal Death GABON 
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